Clinical Trials for Aortic Stenosis

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

NCT ID: NCT06777368

The REdo tranScatheter Aortic Valve Replacement study is looking at a procedure called redo Transcatheter Aortic Valve Replacement (TAVR) for patients with a condition known as aortic stenosis. Thi...

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

NCT ID: NCT05646381

This clinical trial is studying a new treatment called pelacarsen (TQJ230) to see if it can help slow down the worsening of calcific aortic valve stenosis, a condition where the heart's aortic valv...

Post-Market Clinical Follow Up Study With Navitor Valve

NCT ID: NCT06008080

The Navitor Valve clinical trial is studying the safety and effectiveness of a new heart valve system called the Navitor TAVI (Transcatheter Aortic Valve Implantation) for patients with a condition...

Promoting Shared Decision Making for Severe Aortic Stenosis

NCT ID: NCT06171737

Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study

NCT ID: NCT06749145

The DETECT-AS Diagnostic Study is a research trial that is looking at how well artificial intelligence (AI) can help detect aortic stenosis, a condition where the heart's aortic valve narrows and m...

Isolated Surgical Aortic Valve Replacement in Low Risk AS Patients

NCT ID: NCT06924151

This clinical trial is looking at the safety and effectiveness of a procedure called surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis who are considered to be at lo...

A Study of Transcatheter Aortic Valve Replacement Case Selection and Valve Sizing Using the ABC Bicuspid Sizing Algorithm

NCT ID: NCT06991517

This clinical trial is exploring a new method called the ABC Bicuspid Sizing Algorithm to see how it can improve outcomes for patients with a specific heart condition known as bicuspid aortic steno...

A Multicenter, Prospective, Randomized Controlled Trial to Evaluate the Efficacy of PCSK-9 Inhibitors in Delaying the Progression of Calcified Aortic Valve Disease

NCT ID: NCT06996223

This clinical trial is studying a medication called PCSK9 inhibitor to see if it can help slow down the worsening of calcified aortic valve disease, specifically a condition known as aortic stenosi...

Heart Failure and Aortic Stenosis Transcriptome

NCT ID: NCT03268135

This clinical trial is studying heart failure and aortic stenosis, which are serious heart conditions. The researchers want to understand the role of certain types of RNA (which are important for g...

TAVR vs. SAVR Study of VitaFlow Liberty® for Severe BAV Stenosis

NCT ID: NCT06597188

The TAVR vs. SAVR Study is looking at a new treatment option called the VitaFlow Liberty® for patients with severe bicuspid aortic valve stenosis, a condition where the heart's aortic valve does no...

Conscious Sedation With Suprainguinal Facia Iliaca Block Versus Ilioinguinal Iliohypogastric Block for TAVI

NCT ID: NCT06911463

Videodensitometric Angiographic Assessment of AR in the Cath-lab for Intraprocedural Guidance of TAVI in CHINA

NCT ID: NCT06891079

Short-term Exposure to High Altitude in Patients With Asymptomatic Aortic Stenosis

NCT ID: NCT06894550

This clinical trial is investigating the safety of short-term exposure to high altitudes for patients with aortic stenosis, a condition where the heart's aortic valve narrows, affecting blood flow....

General Anesthesia Versus Loco-Regional Anesthesia for Transcarotid Trancatheter Aortic Valve Replacement

NCT ID: NCT06870734

This clinical trial is studying two different types of anesthesia used during a procedure called transcarotid transcatheter aortic valve replacement (TAVR), which is a treatment for a heart conditi...

Comparison of Evolut FX Versus Sapien 3 Ultra Resilia.

NCT ID: NCT06470022

This clinical trial is looking at two different heart valve treatments for a condition called aortic stenosis, which is when the heart's aortic valve narrows and makes it harder for blood to flow. ...

Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

NCT ID: NCT05866640

This clinical trial is investigating the safety and effectiveness of a new device called the F2 Filter, which is designed to protect the brain during a procedure called Transcatheter Aortic Valve R...

Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.

NCT ID: NCT05886517

This clinical trial is studying a procedure called Transcatheter Aortic Valve Implantation (TAVI) for patients with a serious heart condition known as aortic stenosis. Aortic stenosis happens when ...

Application of TAVI at Experienced Interventional Cardiac Centers Without On-site Cardiac Surgery (ATLAS Study)

NCT ID: NCT06818006

The ATLAS Study is a clinical trial aimed at understanding whether the Transcatheter Aortic Valve Replacement (TAVR) procedure can be safely performed in hospitals that do not have on-site cardiac ...

Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement

NCT ID: NCT05739253

This clinical trial is studying how the size of the ascending aorta (the large blood vessel connected to the heart) changes in patients who are undergoing a specific heart procedure called transcat...

Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease

NCT ID: NCT06780241

This clinical trial is studying how different biological factors related to heart valve diseases, like aortic regurgitation and aortic stenosis, can differ between men and women. The researchers wa...