Clinical Trials for Aortic Valve Stenosis

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

NCT ID: NCT05172973

The ALLIANCE AVIV clinical trial is studying the safety and effectiveness of a new heart valve called the SAPIEN X4 Transcatheter Heart Valve (THV) for patients who have a failing aortic bioprosthe...

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

NCT ID: NCT05932615

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

NCT ID: NCT04889872

The PROGRESS clinical trial is studying the safety and effectiveness of a new heart valve treatment called the Edwards SAPIEN 3 for patients with moderate aortic stenosis, a condition where the hea...

Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice

NCT ID: NCT07068633

This study is looking at people with heart valve diseases, which affect the valves that help blood flow through the heart. Specifically, it focuses on patients with moderate to severe problems in t...

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

NCT ID: NCT06557798

This clinical trial, called the REdo Transcatheter Aortic VALVE Implantation study, is looking at a special procedure called Redo TAVI, which is used when a previously implanted heart valve starts ...

First-in-Human (FIH) Study on the Feasibility and Safety of the TaviPilot Augmented Reality Guidance Software

NCT ID: NCT07043075

This clinical trial is testing a new technology called TaviPilot, which uses augmented reality (a type of computer-generated imaging) to help doctors during a procedure called Transcatheter Aortic ...

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement

NCT ID: NCT05672836

This clinical trial is studying a new medication called Enavogliflozin, which is taken once daily, to see if it can help patients with heart conditions after they have had a procedure called transc...

NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study

NCT ID: NCT06269640

The NHLBI SESAME trial is studying a new procedure designed to help people with a heart condition called left ventricular outflow tract obstruction (LVOTO), which occurs when the wall between the h...

Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

NCT ID: NCT07016477

This clinical trial is looking at a new type of imaging called ultra-high resolution photon-counting detector computed tomography (PCD-CT) to better evaluate patients who are scheduled to have a tr...

CardioHeartConnect: Commercially Available Fitness for Cardiac Rehabilitation

NCT ID: NCT07008911

The CardioHeartConnect trial is studying a new way to help patients recover after a heart procedure called transcatheter aortic valve replacement (TAVR). This eight-week program uses Peloton fitnes...

Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication

NCT ID: NCT06049654

The VIVALL-2 study is a clinical trial designed to compare two types of heart valves used in patients who have had a previous aortic valve replacement that is no longer working well. Specifically, ...

Hydra Registry - Italy Experience

NCT ID: NCT05956652

The Hydra Registry - Italy Experience is a study designed to gather information about a treatment called the Hydra TAVI System for patients with a serious heart condition known as aortic valve sten...

Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI

NCT ID: NCT03303612

This clinical trial is investigating two different ways to monitor patients who develop a specific heart condition called left bundle branch block (LBBB) after undergoing a procedure to replace the...

Addressing Under-treatment and Health Equity in AS and MR Using an Integrated EHR Platform

NCT ID: NCT06099665

This clinical trial is studying how automated alerts can help doctors identify and treat patients with severe aortic stenosis (narrowing of the heart's aortic valve) and severe mitral regurgitation...

Clinical Feasibility and Evaluation Study of POINT-GUARD Embolic Protection Device During TAVR (GUARDIAN)

NCT ID: NCT06962371

The GUARDIAN trial is studying a new device called the Point-Guard, which is designed to help protect patients during a procedure known as Transcatheter Aortic Valve Replacement (TAVR). This proced...

Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management

NCT ID: NCT06773780

This clinical trial is studying two different methods of pain relief for patients undergoing a procedure called Transcatheter Aortic Valve Implantation (TAVI), which is used to treat a heart condit...

LANDMARK Trial: a Randomised Controlled Trial of Myval THV

NCT ID: NCT04275726

The LANDMARK Trial is a research study designed to compare a new type of heart valve called Myval THV with two existing heart valves, Sapien and Evolut, in patients suffering from severe aortic val...

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

NCT ID: NCT05909748

This clinical trial is studying a new device called the GEMINUS system, which is designed to help patients with severe symptomatic aortic stenosis, a condition where the heart's aortic valve is nar...

TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics

NCT ID: NCT06896227

This clinical trial is looking at how the positioning of a special heart valve, called a TAVR prosthesis, affects blood flow in the heart and the coronary arteries. The study aims to find out if ce...

Effect of Fetal Aortic Valvuloplasty on Outcomes

NCT ID: NCT05386173

This clinical trial is studying a treatment called fetal aortic valvuloplasty, which involves using a balloon to widen a narrowed aortic valve in unborn babies. This condition is linked to a seriou...