Clinical Trials for Chronic Hepatitis B

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

NCT ID: NCT06425341

This clinical trial is studying a new treatment called HRS-5635 injection for patients with chronic Hepatitis B, a long-lasting infection of the liver. The trial is looking to see how effective and...

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

NCT ID: NCT06993480

This clinical trial is studying a new treatment called AHB-137 injection for people with Chronic Hepatitis B (CHB) who do not have a specific virus marker known as HBeAg. The goal is to see how wel...

A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected Subjects

NCT ID: NCT06990776

This clinical trial is studying a new medication called TQA3605 tablets to see how well it works and how safe it is for people with chronic Hepatitis B who have never received treatment before. The...

VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B

NCT ID: NCT06092333

This clinical trial is exploring the effectiveness of two medications, VIR-2218 and peginterferon alfa-2a, for treating chronic hepatitis B, a viral infection that affects the liver. The goal is to...

Hospital-Based Management of Patients With Chronic Hepatitis B Virus Infection

NCT ID: NCT06966908

A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate

NCT ID: NCT05727267

This clinical trial is testing a new type of vaccine designed to help people with chronic Hepatitis B, which is a long-lasting liver infection. The study is in its early stages and aims to check ho...

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

NCT ID: NCT02932150

This clinical trial is studying a medication called tenofovir alafenamide (TAF) to see how well it works for treating chronic hepatitis B virus (CHB) infection in children and teenagers. The resear...

TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate

NCT ID: NCT06513286

The TherVacB clinical trial is studying a new hepatitis B vaccine designed for people with chronic hepatitis B (CHB) who are already receiving treatment to keep the virus under control. This trial ...

Pegylated Interferon Alfa-2b in Reducing Relapse Rates After Nucleos(t)ide Analogue Withdrawal in HBeAg-negative CHB Patients with Low Level HBsAg

NCT ID: NCT06900166

This clinical trial is investigating how effective a medication called Pegylated Interferon Alfa-2b is in preventing the return of the hepatitis B virus in patients who have been off their antivira...

Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)

NCT ID: NCT03792919

The CNAVK clinical trial is looking at whether some patients with chronic hepatitis B (CHB) can safely stop their long-term antiviral medications, called nucleos(t)ide analogues (NAs), without risk...

HBV-Specific TCR-T Cell Therapy Combined with Nucleos(t)ide Analogues in Chronic Hepatitis B Patients

NCT ID: NCT06885710

This clinical trial is studying a new treatment for patients with chronic Hepatitis B, a viral infection that affects the liver. The treatment combines modified T-cells—specialized immune cells tha...

Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

NCT ID: NCT02863757

This clinical trial is looking at patients who have both Chronic Hepatitis B (CHB) and Nonalcoholic Fatty Liver Disease (NAFLD). The main goal is to understand how these conditions progress over ti...

Treatment of Patients With Chronic Hepatitis B With Hepatitis B Immunoglobulins

NCT ID: NCT05345990

This clinical trial is studying the effectiveness and safety of a treatment called hepatitis B immunoglobulins (HBIG) for patients with chronic Hepatitis B infection. The trial will enroll a total ...

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

NCT ID: NCT06263959

This clinical trial is studying a new medication called GST-HG131 to see if it is safe and effective for patients with chronic hepatitis B, a long-lasting liver infection caused by the hepatitis B ...

Evaluate TQ-A3334 Combined Nucleoside (Acid) Analogs in the First Treatment/Treatment of Chronic HBV Infection

NCT ID: NCT06706310

This clinical trial is studying a new treatment called TQ-A3334 for people with chronic Hepatitis B, a long-term viral infection that affects the liver. The goal is to see how well this treatment w...

Study to Evaluate the Efficacy and Safety of AHB-137 in Treatment-naive Participants with CHB with Low Viral Load

NCT ID: NCT06829329

This clinical trial is studying a new treatment called AHB-137 for people with Chronic Hepatitis B (CHB) who have not been treated before and have a low viral load. The trial will include about 60 ...

MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B

NCT ID: NCT06779058

This clinical trial is studying a new way to check the severity of liver fibrosis (scarring) in people with chronic hepatitis B, a long-term liver infection. The researchers want to see if a non-in...

Molecular Characteristics of Hepatitis B Virus Integration, Mutation, and Drug Resistance

NCT ID: NCT06779864

This clinical trial is studying the characteristics of the Hepatitis B virus (HBV) in patients with chronic Hepatitis B (CHB). The researchers are looking at how the virus changes over time, how it...

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects with Chronic Hepatitis B Virus Infection

NCT ID: NCT06384131

This clinical trial is investigating a new treatment called ABI-4334 for people with chronic Hepatitis B virus (HBV) infection. The study is designed to evaluate how safe the drug is, how it acts i...

Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

NCT ID: NCT05960240

This clinical trial is studying a new medication called AB-101 to see how safe it is and how the body processes it in both healthy adults and people with chronic hepatitis B (CHB). The trial has th...