Clinical Trials for Chronic Rhinosinusitis With Nasal Polyps

Find clinical trials for chronic rhinosinusitis with nasal polyps. Discover research opportunities and treatment options in your area.

32 Active Trials Found

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A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps

NCT ID: NCT06454240

This clinical trial is testing a new treatment called lunsekimig to see how effective it is for adults who have chronic rhinosinusitis with nasal polyps (CRSwNP) and are not getting enough relief f...

Recruiting

Phase: PHASE2 Type: interventional Locations: Leuven, , Belgium, Manchester, , United Kingdom +40 more

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

NCT ID: NCT06834360

This clinical trial is testing a new treatment called itepekimab for people with chronic rhinosinusitis with nasal polyps (CRSwNP), a condition that causes inflammation and swelling in the nasal pa...

Recruiting

Phase: PHASE3 Type: interventional Locations: Marseille, , France, Montpellier, , France +56 more

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

NCT ID: NCT06834347

This clinical trial is studying a medication called itepekimab to see how well it works for people with chronic rhinosinusitis with nasal polyps, a condition that causes long-term nasal congestion ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Montreal, Quebec, Canada, Lund, , Sweden +51 more

A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab

NCT ID: NCT06706817

This clinical trial is studying a medication called tezepelumab to see how well it helps adults with a condition called chronic rhinosinusitis with nasal polyps (CRSwNP), which can cause symptoms l...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, Salamanca, , Spain +40 more

Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study

NCT ID: NCT06914908

This clinical trial is studying the long-term safety and effectiveness of a medication called lunsekimig for adults with chronic rhinosinusitis with nasal polyps (CRSwNP). This study is designed fo...

Recruiting

Phase: PHASE2 Type: interventional Locations: La Jolla, California, United States

Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps

NCT ID: NCT05009758

This clinical trial is focused on understanding how asthma and chronic rhinosinusitis (CRS), particularly when associated with nasal polyps, are connected. Researchers are looking at three groups o...

Recruiting

Phase: NA Type: interventional Locations: Wien, , Austria

Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP

NCT ID: NCT06398873

This clinical trial is looking at how a medication called dupilumab affects the barrier function of the nasal lining in patients with chronic rhinosinusitis (CRS), which can occur with or without n...

Recruiting

Type: observational Locations: Vienna, , Austria

3D Printing to Improve Nasal Irrigation Outcome

NCT ID: NCT06118554

This clinical trial is exploring how 3D printing can help people with chronic rhinosinusitis, a condition that causes long-lasting nasal congestion and sinus issues. The goal is to create a persona...

Recruiting

Phase: NA Type: interventional Locations: Columbus, Ohio, United States

Identifying Predictors Of Response To Mepolizumab In CRSwNP

NCT ID: NCT05902325

This clinical trial is studying how well a medication called mepolizumab works for patients with chronic rhinosinusitis with nasal polyps (CRSwNP), a condition that causes long-lasting nasal conges...

Recruiting

Phase: PHASE4 Type: interventional Locations: Montréal, Quebec, Canada

The Role of IL5 in Epithelial Cell Integrity

NCT ID: NCT05895929

**Clinical Trial Summary: The Role of IL5 in Epithelial Cell Integrity** This clinical trial is studying how a medication called mepolizumab can help people with chronic rhinosinusitis, particular...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Baltimore, Maryland, United States, Baltimore, Maryland, United States

Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis

NCT ID: NCT04869436

This clinical trial is studying how well a medication called dupilumab works for patients with chronic rhinosinusitis and nasal polyps, especially focusing on how it affects the sense of smell. Res...

Recruiting

Phase: PHASE4 Type: interventional Locations: London, Ontario, Canada

Opening the "Black Box" on Tezepelumab's Effect on Chronic Rhinosinusitis With Severe Asthma

NCT ID: NCT06740045

This clinical trial is looking at how a medication called Tezepelumab can help patients who have both severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). These two conditions are c...

Not yet recruiting

Phase: PHASE3 Type: interventional

Immunologic Impact of Dupilumab in Patients Suffering From Asthma and Chronic Rhinosinusitis With Polyps

NCT ID: NCT06556264

This clinical trial is looking at how a medication called dupilumab can help reduce inflammation in adults who have both chronic rhinosinusitis with nasal polyps and moderate to severe asthma. Thes...

Not yet recruiting

Phase: PHASE4 Type: interventional

A Study of GR1802 in Participants With Chronic Sinusitis With Nasal Polyps

NCT ID: NCT06516302

This clinical trial is studying a new treatment called GR1802 for adults with chronic rhinosinusitis with nasal polyps (CRSwNP), a condition that causes ongoing nasal congestion and can lead to sur...

Not yet recruiting

Phase: PHASE3 Type: interventional

A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps

NCT ID: NCT06451640

This clinical trial is studying a new treatment called TQC2731 injection for people suffering from chronic sinusitis with nasal polyps. Chronic sinusitis is a long-lasting inflammation of the sinus...

Recruiting

Phase: PHASE2 Type: interventional Locations: Dalian, Liaoning, China, Changsha, Hunan, China +17 more

Predictive Factors in Chronic Rhinosinusitis With Nasal Polyps

NCT ID: NCT06459622

This clinical trial is designed to study chronic rhinosinusitis with nasal polyps (CRSwNP), a condition that causes inflammation in the nasal passages and can lead to nasal polyps, which are growth...

Not yet recruiting

Phase: NA Type: interventional

Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis

NCT ID: NCT05246267

This clinical trial is studying the effects of a medication called dupilumab on patients with chronic rhinosinusitis with nasal polyps (CRSwNP). The goal is to see if adding dupilumab to standard t...

Recruiting

Type: observational Locations: Bronx, New York, United States

Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab Treatment

NCT ID: NCT05642806

This clinical trial is studying how a medication called Mepolizumab affects the immune system of patients with Chronic Rhinosinusitis, particularly those who also have nasal polyps. Researchers wan...

Recruiting

Phase: PHASE4 Type: interventional Locations: Vancouver, British Columbia, Canada

th2 Modulation CRSwNP

NCT ID: NCT06107101

This clinical trial, called "th2 Modulation CRSwNP," is focused on a condition known as Chronic Rhinosinusitis with Nasal Polyps (CRSwNP), which causes the nasal passages to become swollen and infl...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Vancouver, British Columbia, Canada

Study of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis

NCT ID: NCT06372678

This clinical trial, called the "Study of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis," is looking to see how well a new treatment called CM326 works for people suffering...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

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