Clinical Trials for Cocaine Use Disorder

Find clinical trials for cocaine use disorder. Discover research opportunities and treatment options in your area.

23 Active Trials Found

Showing 23 trials on this page

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Contingency Management for Drug Use: Does Age Matter?

NCT ID: NCT05521854

This clinical trial, titled "Contingency Management for Drug Use: Does Age Matter?", is studying whether using a smartphone app that offers rewards can help older adults who struggle with substance...

Recruiting

Phase: NA Type: interventional Locations: Oconomowoc, Wisconsin, United States, Chicago, Illinois, United States +1 more

Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories

NCT ID: NCT05902819

This clinical trial is studying how a medication called minocycline, which inhibits a specific enzyme (MMP-9), may help change the way people remember and react to traumatic experiences or cocaine ...

Recruiting

Phase: NA Type: interventional Locations: Zürich, , Switzerland

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)

NCT ID: NCT05610072

This clinical trial is studying how certain drugs, specifically n-acetylcysteine (NAC), might help people who are struggling with both opioid and cocaine use disorders. The researchers believe that...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Lexington, Kentucky, United States, Lexington, Kentucky, United States

[C-11]NPA PET-amphetamine in Cocaine Use Disorders

NCT ID: NCT05011760

This clinical trial, titled "[C-11]NPA PET-amphetamine in Cocaine Use Disorders," is researching how the brain responds to a substance called amphetamine in individuals who have cocaine use disorde...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Pittsburgh, Pennsylvania, United States, Pittsburgh, Pennsylvania, United States

Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIV

NCT ID: NCT06691243

This clinical trial is looking at a medication called semaglutide to see if it's safe and effective for adults struggling with cocaine use disorder (CUD), both with and without HIV. If you are an a...

Not yet recruiting

Phase: PHASE2 Type: interventional

Imaging CRF X NOP Interactions in CUD

NCT ID: NCT05008146

This clinical trial is investigating how certain brain receptors, called nociceptive opioid peptide (NOP) receptors, interact with cortisol and corticotrophin-releasing factor (CRF) in people with ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Safety Profile of Psilocybin for Cocaine Use Disorder

NCT ID: NCT06102434

This clinical trial is studying the safety of a substance called psilocybin for people who have a cocaine use disorder. The goal is to see how psilocybin affects the heart and mood when taken by in...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Los Angeles, California, United States

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

NCT ID: NCT04927143

This clinical trial, titled "Encouraging Abstinence Behavior in a Drug Epidemic," is studying how financial incentives can help people struggling with opioid or cocaine use disorders to stay sober....

Recruiting

Phase: NA Type: interventional Locations: Oconomowoc, Wisconsin, United States, Wauwatosa, Wisconsin, United States +1 more

Cariprazine for Comorbid Cocaine and Opioid Use Disorder

NCT ID: NCT05063201

This clinical trial is studying a medication called cariprazine to see if it can help people who have both cocaine and opioid use disorders. Participants in this study will be adults aged 18 to 65 ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Philadelphia, Pennsylvania, United States

Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder

NCT ID: NCT05986578

This clinical trial is investigating a treatment called intermittent theta burst stimulation (iTBS) to see how it affects brain activity in adults struggling with cocaine use disorder. The research...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder

NCT ID: NCT05974202

This clinical trial is studying a new way to help adults with cocaine use disorder by combining a treatment called repetitive transcranial magnetic stimulation (rTMS) with cognitive-behavioral ther...

Not yet recruiting

Phase: NA Type: interventional Locations: New York, New York, United States

Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)

NCT ID: NCT05262270

The CURB-2 trial is a research study designed to find out how effective a combination of two medications—extended-release naltrexone (XR-NTX) and extended-release buprenorphine (XR-BUP)—is in helpi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Little Rock, Arkansas, United States +11 more

Temporal Window and Episodic Future Thinking in CUD

NCT ID: NCT05507814

This clinical trial is studying the relationship between time perception and future thinking in people who have Cocaine Use Disorder (CUD). Researchers want to understand how thinking about the fut...

Recruiting

Phase: NA Type: interventional Locations: Roanoke, Virginia, United States

Exenatide For Reducing the Reinforcing Effects of Cocaine

NCT ID: NCT06252623

This clinical trial is investigating whether a medication called exenatide (also known as Bydureon), which is typically used for treating type 2 diabetes, can help reduce the urge to use cocaine in...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Treating Polysubstance Use Using a Novel Digital Technology

NCT ID: NCT05766631

This clinical trial is studying a new app designed to help people who are dealing with both opioid and cocaine use. The goal is to see if using this app, along with traditional methadone treatment,...

Recruiting

Phase: PHASE3 Type: interventional Locations: Baltimore, Maryland, United States, Baltimore, Maryland, United States +4 more

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

NCT ID: NCT06125054

This clinical trial is studying how a combination of ketamine, a medication often used for pain relief and depression, and special brain training using real-time brain imaging (called neurofeedback...

Recruiting

Phase: PHASE2 Type: interventional Locations: Zürich, , Switzerland

Pioglitazone as an Adjunct to Cognitive-Behavioral Therapy for Cocaine Relapse Prevention

NCT ID: NCT04843046

This clinical trial is studying how well a medication called pioglitazone works when combined with cognitive-behavioral therapy (CBT) to help people who have recently stopped using cocaine stay dru...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Role of Pavlovian Mechanisms for Control Over Substance Use

NCT ID: NCT06701487

This clinical trial is studying how certain learned behaviors might affect substance use, specifically focusing on individuals with alcohol and other substance use disorders. Researchers developed ...

Recruiting

Type: observational Locations: Dresden, , Germany

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

NCT ID: NCT05529927

This clinical trial is studying the use of a medication called sustained-release dexamphetamine to help people with moderate to severe cocaine use disorder. Many individuals struggle with cocaine a...

Not yet recruiting

Phase: PHASE2 Type: interventional

Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

NCT ID: NCT04721418

This clinical trial is looking to understand how cocaine use affects the brain by measuring something called synaptic density, which refers to the connections between brain cells. Researchers want ...

Recruiting

Type: observational Locations: New Haven, Connecticut, United States

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