Clinical Trials for Colorectal Cancer Stage IV

Early Detection of Advanced Adenomas and Colorectal Cancer

NCT ID: NCT06342440

This clinical trial is looking to create a new blood test that can help find colorectal adenomas (precancerous growths) and colorectal cancer early. The goal is to make this test highly sensitive a...

Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer

NCT ID: NCT05171660

This clinical trial is studying a new treatment approach for patients with advanced colorectal cancer that has a specific genetic mutation known as RAS. The researchers want to see how well a combi...

Early Onset Colorectal Cancer Detection

NCT ID: NCT06342401

This clinical trial is focused on finding a new way to detect early-onset colorectal cancer (EOCRC), which is cancer of the colon or rectum diagnosed in people under 50 years old. This type of canc...

Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer

NCT ID: NCT06784947

This clinical trial is studying a new combination treatment for patients with advanced colorectal cancer, specifically those whose cancer is classified as microsatellite stable. The treatment inclu...

Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer

NCT ID: NCT05426005

This clinical trial is investigating a new treatment called Cadonilimab for patients with advanced colorectal cancer that has specific characteristics: it is mismatch repair-deficient (dMMR) or mic...

Predictive and Prognostic Value of Inflammatory Markers and microRNA in Stage IV Colorectal Cancer

NCT ID: NCT04149613

Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer

NCT ID: NCT06509126

This clinical trial is studying two ways to give a cancer treatment called Panitumumab combined with FOLFIRI for patients with advanced colorectal cancer that is located on the left side of the col...

Phase I Study of Combined Immune Cell Therapy in Patients With Stage 4 Colorectal Cancer With Metastatic Lesion Who Failed Prior Standard of Care

NCT ID: NCT06296056

This clinical trial is looking at a new treatment called combined immune cell therapy for patients with stage 4 colorectal cancer that has spread to other parts of the body and has not improved wit...

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

NCT ID: NCT05576896

This clinical trial is investigating whether adding hydroxychloroquine to two standard treatments, encorafenib and cetuximab, can help patients with advanced colorectal cancer that has a specific g...

Fruquintinib Plus Capecitabine Versus Capecitabine as Maintenance Therapy for Metastatic Colorectal Cancer After First-line Chemotherapy

NCT ID: NCT05451719

This clinical trial is studying whether a combination of two medications, fruquintinib and capecitabine, is more effective than capecitabine alone as maintenance therapy for patients with metastati...

Treatment Response Prediction System of mCRC Patients Based on CTC

NCT ID: NCT04917276

This clinical trial is focused on improving treatment for patients with advanced colorectal cancer that has spread to the liver. Researchers want to understand how to detect circulating tumor cells...