Clinical Trials for Cystic Fibrosis

Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.

NCT ID: NCT06364176

This clinical trial is studying whether the medication losartan can help improve the effectiveness of modulator therapy in people with cystic fibrosis (CF). Modulator therapy helps to correct the f...

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

NCT ID: NCT04731272

This clinical trial is studying a medication called dulaglutide to see if it can help improve blood sugar levels in adults with cystic fibrosis who also have issues with glucose tolerance or diabet...

Impact of Sinus Surgery on Individuals With Cystic Fibrosis

NCT ID: NCT04469439

This clinical trial is studying the effects of endoscopic sinus surgery on individuals with cystic fibrosis who also suffer from a condition called chronic rhinosinusitis (CRS), which causes ongoin...

A Study to Test How Well BI 3720931 is Tolerated and Whether it Improves Lung Function in People With Cystic Fibrosis (Lenticlair™ 1)

NCT ID: NCT06515002

This clinical trial is studying a new medication called BI 3720931 to see how well it is tolerated and if it can improve lung function in adults with cystic fibrosis (CF). The trial is open to adul...

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

NCT ID: NCT06747858

This clinical trial is studying a new treatment called ARCT-032 for adults with Cystic Fibrosis (CF), a genetic condition that affects the lungs and digestive system. The trial focuses on people wh...

Project 2 Airway Potential Hydrogen (pH) in Asthma

NCT ID: NCT03617718

This clinical trial, called Project 2 Airway Potential Hydrogen (pH) in Asthma, is exploring a new way to measure the acidity level in the airways of people with asthma and cystic fibrosis. Researc...

Markers of Osteoporosis in Cystic Fibrosis

NCT ID: NCT03921060

This clinical trial, called "Markers of Osteoporosis in Cystic Fibrosis," is looking at how cystic fibrosis (CF) affects bone health. The main study will involve up to 100 participants, including b...

Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes

NCT ID: NCT04530383

This clinical trial is exploring how well the medication metformin can help improve breathing function in people with cystic fibrosis-related diabetes (CFRD). The study aims to see if metformin can...

FEED-Cystic Fibrosis (FEED-CF)

NCT ID: NCT05766774

The FEED-Cystic Fibrosis (FEED-CF) trial is researching how a diet high in sugars might affect blood sugar levels in adults with cystic fibrosis (CF), who are at risk for a specific type of diabete...

An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers

NCT ID: NCT06280066

This clinical trial is studying ways to improve the mental health and resilience of children with cystic fibrosis (CF) and their mothers. Cystic fibrosis is a serious condition that affects the lun...

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

NCT ID: NCT04624490

This clinical trial is looking at a new way to see how well lungs are working using a special type of MRI with a gas called hyperpolarized (HP) 129Xe. The goal is to find out if this imaging techni...

Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic Fibrosis

NCT ID: NCT04166396

This clinical trial is investigating whether antioxidant supplements can help improve exercise tolerance in people with cystic fibrosis (CF). Exercise intolerance means that some patients may find ...

Early Check: Expanded Screening in Newborns

NCT ID: NCT03655223

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

NCT ID: NCT06504589

The REACH study is a research trial designed for people with cystic fibrosis (CF) who do not take specific medications known as CFTR modulators. The main goal of this study is to collect important ...

Trikafta Exercise Study in Cystic Fibrosis

NCT ID: NCT05279040

The Trikafta Exercise Study is looking into how a new medication called Trikafta helps people with cystic fibrosis (CF) breathe better during exercise. Many patients with CF experience shortness of...

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

NCT ID: NCT06296394

This clinical trial, titled "Health Outcomes of Parents With Cystic Fibrosis-Aim 2," aims to understand how becoming a parent affects the health of individuals with cystic fibrosis (CF) in today's ...

High Resolution Micro OCT Imaging

NCT ID: NCT03256773

This clinical trial, called "High Resolution Micro OCT Imaging," is looking at a special type of imaging technology to create detailed pictures of the lungs and nose. Researchers hope that by under...

A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis

NCT ID: NCT06478706

This clinical trial is testing a new inhaled medication called ETD001 in people with cystic fibrosis (CF). The study has two parts. In the first part, researchers want to see if ETD001 is safe for ...

A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

NCT ID: NCT05668741

This clinical trial is studying a new treatment called VX-522 for adults aged 18 and older who have cystic fibrosis (CF) and specific gene mutations that do not respond to existing CF therapies. Th...

Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis

NCT ID: NCT06507956

This clinical trial, called ACTIVMUCO, is studying how much physical activity adults with cystic fibrosis (CF) engage in and how much time they spend being inactive. Cystic fibrosis is a genetic co...