Clinical Trials for Decompensated Cirrhosis

Find clinical trials for decompensated cirrhosis. Discover research opportunities and treatment options in your area.

18 Active Trials Found

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BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HE

NCT ID: NCT06538077

This clinical trial is comparing two treatments—branched-chain amino acids (BCAA) and rifaximin—for patients with cirrhosis who have recently recovered from a serious liver condition called overt h...

Recruiting

Phase: PHASE4 Type: interventional Locations: Chandigarh, , India, Chandigarh, , India +2 more

Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival

NCT ID: NCT06431919

This clinical trial is studying the effects of combining two medications, carvedilol and simvastatin, to see if they can help patients with cirrhotic cardiomyopathy (CCM), a condition that affects ...

Recruiting

Phase: NA Type: interventional Locations: Chandigarh, , India

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

NCT ID: NCT06823713

This clinical trial is studying a new treatment called RTX001, which is a special type of cell therapy designed to help patients with end-stage liver disease, specifically those suffering from cirr...

Recruiting

Phase: PHASE1 Type: interventional Locations: Madrid, , Spain, London, , United Kingdom +10 more

CirrhoCare- Using Smart-phone Technology to Enhance Care and Access to Treatment for Cirrhosis

NCT ID: NCT06223893

The CirrhoCare trial is studying how smartphone technology can help improve care and treatment for patients with decompensated cirrhosis, a serious liver condition. This trial will compare the effe...

Recruiting

Phase: NA Type: interventional Locations: Southampton, , United Kingdom, Birmingham, , United Kingdom +13 more

A Study to See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy

NCT ID: NCT06987968

This clinical trial is investigating a new medicine called VS-01 to see if it can help patients with a serious liver condition known as overt hepatic encephalopathy (OHE). OHE can occur in people w...

Not yet recruiting

Phase: PHASE2 Type: interventional

Hospital @ Home Model of Care for Cirrhosis

NCT ID: NCT06396897

This clinical trial is exploring a new way to care for patients with severe liver disease, known as decompensated cirrhosis, through a program called Health at Home (H@H). The goal of the study is ...

Recruiting

Phase: NA Type: interventional Locations: Indianapolis, Indiana, United States

Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-2)

NCT ID: NCT05224960

This clinical trial, called MSC-DLC-2, is exploring the use of mesenchymal stem cells (MSCs) to treat patients with decompensated cirrhosis, a serious liver condition that can lead to severe compli...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China, Wuhan, Hubei, China +6 more

Trial Comparing Conventional Antibiotic Strategies Versus Regimens Guided by Epidemiological Surveillance in Infected Patients With Cirrhosis (SURVIC_STUDY)

NCT ID: NCT05783661

The SURVIC_STUDY is a clinical trial designed to compare two different approaches to treating bacterial infections in patients with a serious liver condition called cirrhosis. The study aims to fin...

Recruiting

Phase: PHASE4 Type: interventional Locations: Barcelona, , Spain

Fecal Microbiome Transplantation in Cirrhosis: Trial in Patients With Decompensated Cirrhosis

NCT ID: NCT06533852

This clinical trial is studying a treatment called Fecal Microbiota Transplantation (FMT) for patients with decompensated cirrhosis, which is a serious liver condition where the liver cannot functi...

Not yet recruiting

Phase: PHASE3 Type: interventional

Prospective Cohort Study of Complications and Outcomes in Cirrhosis

NCT ID: NCT06374511

This clinical trial is studying the complications and outcomes in patients with a severe liver condition called decompensated cirrhosis. The researchers want to understand how common certain compli...

Recruiting

Type: observational Locations: Guangzhou, Guangdong, China

Effect of IMO on Intestinal Microbiota Translocation in Cirrhosis

NCT ID: NCT06134544

This clinical trial is looking at whether a substance called isomaltooligosaccharides (IMO) can help protect patients with liver cirrhosis from the harmful effects of bacteria moving from the gut i...

Recruiting

Phase: NA Type: interventional Locations: Guangzhou, Guangdong, China

Incidence & Predictive Factors of Recompensation in Children With Decompensated Cirrhosis as Per the Baveno VII Criteria

NCT ID: NCT06344611

This clinical trial is focusing on understanding how often and under what conditions children with a serious liver condition called decompensated cirrhosis can improve or "recompensate" after treat...

Not yet recruiting

Type: observational Locations: New Delhi, Delhi, India

Rotational Thromboelastometry Versus Conventional Haemostatic Tests in Children With Decompensated Cirrhosis Undergoing Invasive Procedures.

NCT ID: NCT05734001

This clinical trial is studying a new method called ROTEM (Rotational Thromboelastometry) to help guide blood transfusions for children with decompensated cirrhosis who need to undergo certain medi...

Recruiting

Phase: NA Type: interventional Locations: New Delhi, , India

A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis

NCT ID: NCT06306781

This clinical trial is looking at a new treatment called HCL001 cell injection for patients with decompensated cirrhosis, a serious liver condition. The goal of the study is to find out if this tre...

Not yet recruiting

Phase: NA Type: interventional

To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated Cirrhosis

NCT ID: NCT06147518

This clinical trial is investigating how well two different diabetes medications, Dapagliflozin plus Metformin and Sitagliptin plus Metformin, work for people who have diabetes and liver cirrhosis....

Not yet recruiting

Phase: NA Type: interventional Locations: New Delhi, Delhi, India

Rifaximin for Preventing Progression and Complications in Patients With Decompensated Liver Cirrhosis

NCT ID: NCT05863364

This clinical trial is investigating whether a medication called rifaximin can help prevent the worsening of liver cirrhosis and its complications in patients who have a more severe form of the dis...

Recruiting

Phase: NA Type: interventional Locations: Shanghai, , China

Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)

NCT ID: NCT05984303

This clinical trial, called MSC-DLC-1b, is studying the safety of using special cells derived from human umbilical cords to treat patients with decompensated cirrhosis, a serious liver condition. T...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China

Efficacy of High Dose Albumin Therapy in Improving Liver Transplant-free Survival in Patients With Acute Decompensation of Cirrhosis

NCT ID: NCT05956197

This clinical trial is studying the effects of a high-dose albumin treatment on patients who have severe liver problems known as acute decompensation of cirrhosis. The main goal is to see if giving...

Not yet recruiting

Type: observational Locations: New Delhi, Delhi, India

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