Clinical Trials for Dermatomyositis

Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis

NCT ID: NCT06857240

This clinical trial is studying the use of a cream called ruxolitinib to treat skin symptoms in adults with dermatomyositis—an autoimmune condition that causes skin rashes and muscle weakness. The ...

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

NCT ID: NCT05979441

Study of Deucravacitinib for Refractory Adults With Dermatomyositis/Juvenile Dermatomyositis

NCT ID: NCT07012057

This clinical trial is studying a new medication called deucravacitinib for adults with dermatomyositis or juvenile dermatomyositis, which are autoimmune diseases that cause muscle weakness and ski...

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy

NCT ID: NCT06154252

The RESET-Myositis trial is studying a new treatment called CABA-201 for people with active idiopathic inflammatory myopathy, a group of diseases that cause muscle weakness and inflammation. This s...

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

NCT ID: NCT03816345

This clinical trial is studying how well a medication called nivolumab works for patients who have autoimmune disorders and advanced cancers that are difficult to treat or remove with surgery. Nivo...

Environmental Risk Factors for the Anti-synthetase Syndrome

NCT ID: NCT01276470

This clinical trial is studying the connection between environmental factors and a specific autoimmune disorder called anti-synthetase syndrome, which involves muscle weakness and lung issues. Rese...

Adult and Juvenile Myositis

NCT ID: NCT00017914

This clinical trial is focused on understanding myositis, an inflammatory muscle disease that affects both adults and children. The study aims to learn more about the causes of myositis and how it ...

A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies

NCT ID: NCT06698796

This clinical trial is looking at how a medicine called dazukibart works for people with two muscle disorders known as dermatomyositis (DM) and polymyositis (PM). These conditions cause inflammatio...

Photoacoustic/Ultrasound Imaging in Patients of Dermatomyositis With Calcinosis Cutis: Characteristic Findings and Treatment Response Evaluation

NCT ID: NCT07037472

This clinical trial is studying a new, non-invasive imaging technique called photoacoustic and ultrasound (PA/US) imaging to better understand and monitor skin problems in people with dermatomyosit...

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis

NCT ID: NCT06284954

This clinical trial is studying a new medication called empasiprubart to see if it is safe and effective for adults with dermatomyositis, a condition that causes muscle weakness and skin rashes. Th...

DR-0201 in Subjects With Autoimmune Diseases

NCT ID: NCT06647069

This clinical trial, called DR-0201, is looking at a new treatment for people with certain autoimmune diseases, including systemic lupus erythematosus (SLE), cutaneous lupus, Sjögren's syndrome, an...

Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress

NCT ID: NCT06999109

This clinical trial, called Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress (TEAM-LEADS), is looking to see if a special program can help ...

Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis

NCT ID: NCT06298019

This clinical trial is studying a new treatment called KYV-101, which is a type of cell therapy for adults with dermatomyositis, an autoimmune disease that causes muscle weakness and skin rashes. T...

Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases

NCT ID: NCT06685042

The CATARSIS study is exploring a new treatment called anti-CD19 CAR T-cell therapy for people with severe autoimmune diseases that haven't responded to other treatments. These conditions include l...

Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study

NCT ID: NCT03582800

This clinical trial is studying the use of a medication called sodium thiosulfate (STS) to treat ectopic calcifications or ossifications, which are hard deposits that can form in soft tissues due t...

Intralesional Injection of STS in Treatment of Calcinosis

NCT ID: NCT06672822

This clinical trial is studying a new treatment for people who have calcinosis, which is the buildup of calcium deposits in the skin, often seen in conditions like systemic sclerosis, dermatomyosit...

Study of NM8074 in Patients with Dermatomyositis (DM)

NCT ID: NCT06887738

This clinical trial is studying a new treatment called NM8074 for patients with Dermatomyositis (DM), a condition that causes muscle weakness and skin rashes. The trial is in Phase II, which means ...

Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)

NCT ID: NCT02945345

This clinical trial is studying dermatomyositis, a condition that affects the skin and muscles, using a tool called the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI). The goal i...

Rheumatology Patient Registry and Biorepository

NCT ID: NCT04402086

The Rheumatology Patient Registry and Biorepository is a clinical trial aimed at improving our understanding of various rheumatic diseases, including conditions like rheumatoid arthritis, lupus, an...

Baricitinib in Patients with Relapsing or Naïve Dermatomyositis

NCT ID: NCT04972760

This clinical trial, called BIRD, is studying a medication called baricitinib to see if it can help people with dermatomyositis (DM), a rare condition that can cause muscle weakness and skin proble...