Clinical Trials for Endothelial Dysfunction

Find clinical trials for endothelial dysfunction. Discover research opportunities and treatment options in your area.

56 Active Trials Found

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Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal

NCT ID: NCT05939934

This clinical trial is studying a device called the mandibular advancement device (MAD) to see how it helps people with obstructive sleep apnea (OSA) when they need to stop using their usual treatm...

Recruiting

Phase: NA Type: interventional Locations: Angers, , France

Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury

NCT ID: NCT06825143

This clinical trial is exploring a treatment using lactate, a natural substance in our bodies that helps produce energy, to see if it can reduce damage to blood vessels in adults who are at high ri...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Gunnison, Colorado, United States

Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study

NCT ID: NCT06758648

This clinical trial is looking at how blood vessels in the eye behave in patients with Fabry disease, a genetic condition that can cause various health issues, including problems with blood vessels...

Recruiting

Type: observational Locations: München, Bavaria, Germany

Assessment of Dapagliflozin on Vascular Health in Patients With Type 2 Diabetes

NCT ID: NCT05139914

This clinical trial is studying how a medication called dapagliflozin affects the health of blood vessels in patients with Type 2 Diabetes Mellitus (T2DM). People with T2DM often experience changes...

Recruiting

Phase: PHASE4 Type: interventional Locations: Boston, Massachusetts, United States

Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome

NCT ID: NCT06723002

This clinical trial is studying the effects of olive leaf extract on patients who have experienced a recent acute coronary syndrome (ACS) event, which is a serious condition related to heart proble...

Not yet recruiting

Phase: PHASE2 Type: interventional

Role of Inflammation in Vascular Phenotype Associated with E-cigarette Use

NCT ID: NCT06489249

This clinical trial is investigating how e-cigarette use, also known as vaping, affects blood vessel health, particularly focusing on inflammation and a condition called endothelial dysfunction. En...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Iowa City, Iowa, United States, Iowa City, Iowa, United States

Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

NCT ID: NCT06547619

This clinical trial is focused on understanding how a substance called endothelin-1 affects small blood vessel function in women who have had gestational diabetes (GDM). Women with GDM are at a hig...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Iowa City, Iowa, United States

Sodium Lowering Vascular Effects Trial

NCT ID: NCT05388032

The Sodium Lowering Vascular Effects Trial is studying how reducing dietary sodium (salt) can affect heart and blood vessel health, particularly in people with high blood pressure. The goal is to u...

Recruiting

Phase: NA Type: interventional Locations: New Orleans, Louisiana, United States

Optimizing Pulsatility During Cardiopulmonary Bypass

NCT ID: NCT05344573

This clinical trial is studying how different types of blood flow during heart surgery, specifically using a method called cardiopulmonary bypass, can affect the function of organs like the kidneys...

Recruiting

Type: observational Locations: Aurora, Colorado, United States

Microvascular Dysfunction in Obesity

NCT ID: NCT04087655

This clinical trial is studying how exercise affects blood vessel function in people who are obese. It specifically looks at a process called oxidative stress, which can harm blood vessels and lead...

Recruiting

Phase: NA Type: interventional Locations: Tallahassee, Florida, United States

Centella Asiatica in Older Adults

NCT ID: NCT06472791

This clinical trial is looking at how a dietary supplement called centella asiatica affects blood vessel health in older adults. The study aims to see if this natural supplement can improve the fun...

Not yet recruiting

Phase: NA Type: interventional Locations: Portland, Oregon, United States

Infusion of Prostacyclin Vs Placebo for 72-hours in Mechanically Ventilated Patients with Acute Respiratory Failure

NCT ID: NCT06319274

This clinical trial is studying the effects of a medication called iloprost in patients who are on a ventilator due to severe breathing problems caused by infections. The researchers want to see if...

Recruiting

Phase: PHASE2 Type: interventional Locations: Herlev, , Denmark, Copenhagen, , Denmark +2 more

Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes

NCT ID: NCT05478707

This clinical trial is looking at new ways to improve blood flow in the small blood vessels of people with type 1 diabetes (T1D). It aims to find out if a medication called dulaglutide, which helps...

Recruiting

Phase: PHASE2 Type: interventional Locations: Charlottesville, Virginia, United States

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

NCT ID: NCT05703126

This clinical trial is investigating how to better detect heart problems in patients with acute myeloid leukemia (AML) who are receiving a specific type of chemotherapy called anthracyclines. These...

Recruiting

Phase: NA Type: interventional Locations: Samara, Samara Region, Russian Federation

Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis

NCT ID: NCT06626984

This clinical trial is looking at new and existing treatments to help improve blood flow and protect blood vessels during a serious condition called sepsis, which happens when the body has a severe...

Not yet recruiting

Phase: PHASE1 Type: interventional

Effect of Propionic Acid Supplementation on Endothelial Function

NCT ID: NCT05135702

This clinical trial is looking at whether a dietary supplement called sodium propionate can improve blood vessel function in patients with coronary artery disease (CAD). CAD is a condition where th...

Not yet recruiting

Phase: NA Type: interventional

Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals

NCT ID: NCT05808686

This clinical trial is investigating how small blood vessels in older adults respond to the challenges of high-intensity exercise. Researchers want to see if a safe technique called ischemic condit...

Recruiting

Phase: PHASE2 Type: interventional Locations: Wauwatosa, Wisconsin, United States

Role of Endothelial Function in SCI CVD Risk

NCT ID: NCT06443151

This clinical trial is studying how spinal cord injuries affect the health of blood vessels and the risk of heart disease. People with spinal cord injuries often face an increased risk of heart att...

Recruiting

Type: observational Locations: Englewood, Colorado, United States

Effects of Anesthesia Technique on Endothelial Function

NCT ID: NCT06515028

This clinical trial is studying how two different methods of anesthesia—general anesthesia, which makes you completely unconscious, and infraclavicular block, which numbs the arm—affect the body's ...

Not yet recruiting

Phase: NA Type: interventional

Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women

NCT ID: NCT04530916

This clinical trial is studying the effects of wild blueberries on heart health in middle-aged and older men who have elevated blood pressure or stage 1 hypertension. The researchers want to see if...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fort Collins, Colorado, United States

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