Clinical Trials for Healthy Participants

Find clinical trials for healthy participants. Discover research opportunities and treatment options in your area.

72 Active Trials Found

Showing 72 trials on this page

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A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants

NCT ID: NCT06547164

This clinical trial is investigating how a medication called camizestrant affects the body’s processing of another drug called midazolam when taken repeatedly. It also looks at how camizestrant is ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harrow, , United Kingdom

A Study to Investigate the Relative Bioavailability of 2 Different Formulations of AZD4144, the Effect of Food and Omeprazole on the Pharmacokinetics of AZD4144 in Healthy Participants

NCT ID: NCT06948006

This clinical trial is studying a medication called AZD4144 to understand how well two different formulations of the drug work in the body. Researchers want to find out how food and another medicat...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harrow, , United Kingdom

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

NCT ID: NCT06132841

This clinical trial is looking at a new medication called AZD6234 to see how safe it is, how well it is tolerated, and how it behaves in the body when given repeatedly to healthy adults who are ove...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harrow, , United Kingdom, Glendale, California, United States +3 more

A Study of LY4060874 in Healthy Participants

NCT ID: NCT06709820

This clinical trial is testing a new medication called LY4060874 to see how safe it is and how well people can tolerate it. The study is open to healthy participants aged between 18 and 65, and it ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Singapore, , Singapore, Dallas, Texas, United States

A Study to Investigate the Pharmacokinetics of AZD2389 in Healthy Participants When Administered Alone and in Combination With Quinidine

NCT ID: NCT06974565

This clinical trial is looking to understand how a medication called AZD2389 is processed in the body when taken alone and also when combined with another drug called quinidine. The study will invo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brooklyn, Maryland, United States

A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants

NCT ID: NCT06973005

This clinical trial is designed to study how a medication called AZD2389 affects the way the body processes other drugs, specifically midazolam, caffeine, and bupropion. The trial will involve heal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brooklyn, Maryland, United States

Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)

NCT ID: NCT06919991

This clinical trial, titled "Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants," is looking to understand how certain medications affect the way a new drug called casdatifan w...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tempe, Arizona, United States

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

NCT ID: NCT06948747

This clinical trial is designed to study how a new drug called AZD5004 affects the levels and actions of several other medications, including Rosuvastatin, Atorvastatin, Simvastatin, and Repaglinid...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brooklyn, Maryland, United States

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

NCT ID: NCT06564389

This clinical trial, called the PF-07832837 study, is investigating the safety and tolerability of a new medication in healthy adults and those suffering from moderate to severe atopic dermatitis, ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Anaheim, California, United States

A Study to Investigate the Safety, Tolerability and Pharmacodynamics of AZD4144 in Participants With Obesity

NCT ID: NCT06942923

This clinical trial is designed to test a new medication called AZD4144 in people who are living with obesity. The main goals of the study are to see if the medication is safe to take, how well it ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Berlin, , Germany, Freiburg, , Germany

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants

NCT ID: NCT06491550

This clinical trial is investigating a new drug called AZD4144 to see how safe it is, how well it is tolerated, and how it works in the body, compared to a placebo (a substance with no active treat...

Recruiting

Phase: PHASE1 Type: interventional Locations: Glendale, California, United States, Brooklyn, Maryland, United States

taVNS Effects on Fear Ratings in Naturalistic Context

NCT ID: NCT06975124

This clinical trial is studying how a specific type of stimulation, called transcutaneous auricular vagus nerve stimulation (taVNS), affects how people feel fear while watching a scary movie. In th...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chengdu, Sichuan, China

A Study to Learn How a Tablet Compared With an IV Infusion of the Study Medicine Called Vepdegestrant is Taken up Into the Blood in Healthy Adults

NCT ID: NCT06911788

This clinical trial is studying a medication called Vepdegestrant to see how well it is absorbed into the bloodstream when taken as a tablet compared to an intravenous (IV) infusion. The goal is to...

Recruiting

Phase: PHASE1 Type: interventional Locations: Groningen, , Netherlands, Utrecht, , Netherlands

A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

NCT ID: NCT06961747

This clinical trial is designed to study how a medication called zilucoplan, which is given through an injection, affects breast milk in healthy women who are breastfeeding. The researchers want to...

Not yet recruiting

Phase: PHASE1 Type: interventional

A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers

NCT ID: NCT06951880

This clinical trial is designed to study a new medication called AZD4916 to see how safe it is and how the body processes it in healthy adults. The main goal is to ensure that the drug is safe for ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Harrow, , United Kingdom

Study to Evaluate Drug Levels of Various Solid Gastro-retentive Formulations of Deucravacitinib (BMS-986165) in Healthy Participants

NCT ID: NCT06566768

This clinical trial is looking at a new medication called deucravacitinib, specifically how different versions of it can stay in the stomach longer. The goal is to understand how these formulations...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nottingham, Nottinghamshire, United Kingdom, Nottingham, Nottinghamshire, United Kingdom +1 more

A Study to Investigate the Impact of Multiple Doses of Itraconazole on AZD5004 in Healthy Participants and Multiple Doses of AZD5004 on Combined Oral Ethinyl Oestradiol and Levonorgestrel in Healthy Female Participants

NCT ID: NCT06942936

This clinical trial is exploring how two medications interact with each other in healthy people. In the first part of the study, researchers will look at how multiple doses of a drug called itracon...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Berlin, , Germany, Baltimore, Maryland, United States

The Effect of Exercise on Metabolic Alteration

NCT ID: NCT06923163

This clinical trial is exploring how aerobic exercise, like running, can help manage obesity in adults. Researchers want to understand how much energy people use during exercise and why this energy...

Recruiting

Phase: NA Type: interventional Locations: Shenzhen, Guang Dong, China

A Phase I Study of CDX-622

NCT ID: NCT06650761

This clinical trial, titled "A Phase I Study of CDX-622," is looking into the safety of a new treatment called CDX-622 in healthy volunteers. The researchers want to ensure that this treatment is s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tempe, Arizona, United States

A First-in-human Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of UCB3101 in Healthy Participants

NCT ID: NCT06555601

This clinical trial is studying a new medication called UCB3101 to see if it is safe for healthy adults. The researchers want to find out how well the drug is tolerated when given in increasing dos...

Recruiting

Phase: PHASE1 Type: interventional Locations: Edegem, , Belgium

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