Clinical Trials for Heart Failure With Preserved Ejection Fraction

Find clinical trials for heart failure with preserved ejection fraction. Discover research opportunities and treatment options in your area.

90 Active Trials Found

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Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06536309

This clinical trial is studying a medication called sacubitril/valsartan to see if it can help reduce heart muscle scarring (myocardial fibrosis) in patients with heart failure who still have good ...

Not yet recruiting

Phase: PHASE4 Type: interventional

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

NCT ID: NCT04237701

This clinical trial, called the Yale HF Registry, is focused on monitoring heart failure in patients at the Yale New Haven Health System. Heart failure is a serious condition where the heart strugg...

Type: observational Locations: New Haven, Connecticut, United States

HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

NCT ID: NCT05873634

The HeartShare trial is studying heart failure, a condition where the heart struggles to pump blood effectively, leading to symptoms like shortness of breath and fatigue. The goal of the study is t...

Type: observational Locations: Chicago, Illinois, United States, Rochester, Minnesota, United States +4 more

Study of HS135 in Obese Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06581159

This clinical trial is investigating a new treatment called HS135 for obese patients who have two specific health issues: pulmonary hypertension (high blood pressure in the lungs) and heart failure...

Phase: PHASE1 Type: interventional Locations: Kansas City, Missouri, United States, Phoenix, Arizona, United States +1 more

SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

NCT ID: NCT05138575

The SAK HFpEF Trial is a study looking at how certain medications might help people with a condition called Heart Failure with Preserved Ejection Fraction (HFpEF). Specifically, the trial is testin...

Phase: PHASE2 Type: interventional Locations: Philadelphia, Pennsylvania, United States

Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06114498

This clinical trial is focused on understanding patients with a specific type of heart failure known as heart failure with preserved ejection fraction (HFpEF). The researchers aim to create a detai...

Type: observational Locations: Moscow, , Russian Federation, Moscow, , Russian Federation

HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06391710

The clinical trial titled "HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction" is investigating a new treatment called HRS9531 for people who are obese and have...

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

Study of JK07 in Patients With Chronic Heart Failure

NCT ID: NCT06369298

This clinical trial is testing a new medication called JK07 for patients with chronic heart failure, which is when the heart struggles to pump blood effectively. The study is looking at two groups ...

Phase: PHASE2 Type: interventional Locations: Cleveland, Ohio, United States, Boston, Massachusetts, United States +76 more

Physical Activity, Cardiac and Skeletal Muscle Energetics in Healthy Subjects and HFpEF Patients

NCT ID: NCT04998877

This clinical trial is investigating how physical activity and heart health are connected in people with a specific type of heart failure, known as heart failure with preserved ejection fraction (H...

Type: observational Locations: Baltimore, Maryland, United States

EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease

NCT ID: NCT06249945

This clinical trial is studying the effects of a medication called empagliflozin in patients who have heart failure with preserved ejection fraction (HFpEF) and are on dialysis due to end-stage ren...

Phase: PHASE4 Type: interventional Locations: Taipei, , Taiwan, Hsinchu, , Taiwan

Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation

NCT ID: NCT06027307

The Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation (EVENT) is a research study that is looking at a new medication called enavogliflozin to see if it can help patients with hear...

Phase: PHASE3 Type: interventional Locations: Incheon, , Korea, Republic Of, Seoul, , Korea, Republic Of +4 more

A Preliminary Study for INFORMED

NCT ID: NCT05585125

This clinical trial, called INFORMED, is looking at a new way to help older adults with a specific type of heart failure called Heart Failure with Preserved Ejection Fraction (HFpEF). The study wil...

Phase: PHASE4 Type: interventional Locations: New York, New York, United States

Manganese-enhanced Magnetic Resonance Imaging (MEMRI) in Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06652763

This clinical trial is studying how a special type of MRI, called manganese-enhanced magnetic resonance imaging (MEMRI), can help us understand heart failure with preserved ejection fraction (HFpEF...

Type: observational Locations: Leicester, , United Kingdom

The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF)

NCT ID: NCT06702501

The REIMAGINE-HFpEF study is looking into a new way to help patients with heart failure who have a preserved ejection fraction, meaning their hearts can pump blood but still cause symptoms like sev...

Not yet recruiting

Phase: NA Type: interventional

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

NCT ID: NCT06517186

This clinical trial, titled "Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction," aims to better understand heart failure, specifically when the heart pumps normally but still ...

Type: observational Locations: Chicago, Illinois, United States, Rochester, Minnesota, United States +4 more

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

NCT ID: NCT05887271

This clinical trial is studying whether a low-energy diet can help improve heart function and physical abilities in people with heart failure with preserved ejection fraction (HFpEF). HFpEF is a co...

Phase: PHASE2 Type: interventional Locations: Leicester, Leicestershire, United Kingdom, Manchester, , United Kingdom +1 more

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

NCT ID: NCT02901184

The SPIRRIT trial is studying whether adding a medication called spironolactone to standard heart failure care can help patients with heart failure that preserves its pumping ability (known as hear...

Phase: PHASE3 Type: interventional Locations: Birmingham, Alabama, United States, Boston, Massachusetts, United States +84 more

Purinergic Signaling and the Postmenopausal Heart

NCT ID: NCT06015776

This clinical trial, titled "Purinergic Signaling and the Postmenopausal Heart," is studying how changes in hormone levels after menopause may affect the heart, specifically looking at a type of he...

Type: observational Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Remote Ischaemic Conditioning (RIC) in Heart Failure

NCT ID: NCT06616233

This clinical trial is investigating a treatment called remote ischaemic conditioning (RIC) combined with exercise to see how it affects blood flow to the heart in people with heart failure or thos...

Phase: NA Type: interventional Locations: Leicester, Leics, United Kingdom

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure

NCT ID: NCT05824923

This clinical trial is studying a new treatment called pulmonary artery denervation (PADN) for patients with heart failure who also have pulmonary hypertension, which is high blood pressure in the ...

Phase: PHASE3 Type: interventional Locations: Shenyang, Liaoning, China

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