Clinical Trials for Heart Transplantation

The Evolution of Systemic Microvascular Reactivity in Heart Transplant Patients

NCT ID: NCT05729009

This clinical trial is studying how blood vessels respond in heart transplant patients over time. Researchers want to understand the way these small blood vessels work, which could help improve the...

ZeroHeart Biopsy - Prediction of Deceased Donor Heart Transplant Performance From Organ Donors Using Pre-Transplant Biopsies - A Pilot Study

NCT ID: NCT06982404

The ZeroHeart Biopsy study is looking into whether testing small samples of heart tissue from organ donors can help predict how well a transplanted heart will function in patients. The researchers ...

Haemoadsorption During Heart Transplantation

NCT ID: NCT05270902

This clinical trial is studying a treatment called haemoadsorption (HA) during heart transplantation, which is a surgery to replace a damaged heart with a healthy one. The goal is to see if using H...

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

NCT ID: NCT05909150

This clinical trial is studying whether a special type of salt water solution, called hypertonic saline, can help prevent kidney problems after a heart transplant. Acute kidney injury can happen sh...

Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease

NCT ID: NCT06325280

This clinical trial, titled "Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease," is studying how children's hearts and muscles work together during exercise, especia...

Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation

NCT ID: NCT06813443

This clinical trial is looking to better understand cardiomyopathy, a condition that affects the heart muscle and can lead to heart failure or the need for a heart transplant. Researchers want to f...

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Prevent Rejection in Heart Transplant Children

NCT ID: NCT04924491

This clinical trial is studying a new treatment approach to help prevent heart transplant rejection in young children. Researchers are focusing on a special type of immune cell called regulatory T ...

Belatacept in De Novo Heart Transplantation

NCT ID: NCT04477629

This clinical trial is studying a medication called Belatacept, which is used to help prevent the body from rejecting a new heart after a transplant. The main goal of the study is to see if Belatac...

Precision Medicine in the Management of Heart Transplant Recipients

NCT ID: NCT06774794

This clinical trial is focused on improving the care of heart transplant patients by using a special approach that combines different types of medical information, including blood tests, imaging sc...

CARdiac Imaging and BIomarkers in the Diagnosis of Antibody Mediated Rejection in Heart Transplantation

NCT ID: NCT06774365

This clinical trial is focused on understanding how certain heart issues, specifically inflammation and scarring, can occur in people who have received a heart transplant. The researchers want to s...

Use of Machine-learning Algorithms, Biomarkers and Measures of Quality of Life to Personalize Medical Management of Liver and Heart Transplant Recipients

NCT ID: NCT06774768

This clinical trial is studying how advanced computer technology, known as machine-learning algorithms, can help improve the medical care of adults who have received heart or liver transplants. The...

Electronic Register on Advanced Heart Failure and Transplantation di Cuore

NCT ID: NCT06773611

This clinical trial, called the Electronic Register on Advanced Heart Failure and Transplantation, aims to gather important information about patients who have Advanced Heart Failure or have receiv...

The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients

NCT ID: NCT03292861

Preventive Catheter Ablation for Ventricular arrhythmiaS in Patients With End-sTage Heart faiLure

NCT ID: NCT06556485

The CASTLE-VT clinical trial is studying a treatment called catheter ablation to help prevent dangerous heart rhythms in patients with severe heart failure. This trial specifically looks at individ...

Quantiferon CMV to Identify Treatment Need for Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT)

NCT ID: NCT06341543

The QUANTIFOT clinical trial is studying how a specific blood test, called the QuantiFERON-CMV (QF-CMV), can help identify solid organ transplant recipients who have a mild cytomegalovirus (CMV) in...

Study of Organ Perfusion in Heart Transplantation in Children

NCT ID: NCT06032195

This clinical trial is studying two different solutions used to preserve hearts before they are transplanted into children. The main goal is to see if a new solution called Custodiol-N is safe to u...

First Clinical Evaluation of Heart Transplantation With Grafts Preserved Using an Ex-vivo Extended Perfusion System

NCT ID: NCT06035991

This clinical trial, called PEGASE, is exploring a new method for heart transplantation. It aims to see if using a special device called an ex-vivo perfusion system can help keep a donated heart he...

Genomics in Heart Transplants

NCT ID: NCT06012162

This clinical trial, titled "Genomics in Heart Transplants," is studying how genetics and lifestyle factors affect the success of heart transplants. Researchers will analyze data from 200 heart tra...

IMPact of Donor Heart Function on Recipient Outcomes - a prospectiVE Study to Increase the Utilization of Donor HEARTs

NCT ID: NCT04393181

This clinical trial, called "IMPACT of Donor Heart Function on Recipient Outcomes," is studying how the condition of donor hearts affects the health of patients receiving heart transplants. Many po...

Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging

NCT ID: NCT05081115

The Stress Echo 2030 trial is studying a new way to use heart imaging, called the ABCDE-(FGLPR) protocol, to better understand and treat various heart conditions like coronary artery disease, heart...