Clinical Trials for Hematologic Malignancy

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

NCT ID: NCT06856226

This clinical trial is studying how our genes affect how medications are processed in patients who receive a special treatment called allogeneic hematopoietic stem cell transplant (HSCT). After thi...

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

NCT ID: NCT06401356

This clinical trial is an extension study for patients who have already participated in earlier studies using a medication called pelabresib. The main goal of this trial is to allow those patients ...

Implementation of an Oral Chemotherapy Adherence Intervention

NCT ID: NCT06989489

This clinical trial is studying a new program designed to help patients better stick to their oral cancer medications. The goal is to see how effective this program is in improving medication adher...

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

NCT ID: NCT05600933

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

NCT ID: NCT06579469

This clinical trial is looking to understand the short-term and long-term side effects of CAR-T cell therapy in young patients with certain types of blood cancers and solid tumors. Researchers want...

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

NCT ID: NCT06326463

This clinical trial is studying a new treatment called CAR T-cell therapy specifically for young patients (up to 21 years old) who have certain hard-to-treat blood cancers, such as acute myelogenou...

Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT07014449

This clinical trial is studying a new treatment called WBC100 capsules for patients with relapsed or refractory acute myeloid leukemia (R/R AML), which means their cancer has returned or has not re...

A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant

NCT ID: NCT07006506

This clinical trial is studying a medication called belumosudil to see if it can help prevent a condition known as graft-versus-host disease (GVHD) in people who have received a stem cell transplan...

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

NCT ID: NCT05529069

This clinical trial is studying the combination of two medications, pirtobrutinib and venetoclax, to see if they can help control mantle cell lymphoma (MCL) in patients whose cancer has come back o...

FDG-PET as an Imaging Modality to Diagnose and Risk Stratify Subclinical, Imaging Negative Ici-Myocarditis

NCT ID: NCT06566209

This clinical trial is looking at a special type of imaging called Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) to help diagnose a condition called subclinical immune checkpoint inhibi...

Mosaic Trial for Stem Cell Transplant Recipients

NCT ID: NCT06960993

The Mosaic Trial is a research study designed to see if a special website can help adults with blood cancer who are getting stem cell transplants. The study will compare the experiences of patients...

Prospective Validation of the OHI Index

NCT ID: NCT05882175

**Clinical Trial Summary: Prospective Validation of the OHI Index** This clinical trial is studying a new way to diagnose and predict outcomes for patients with a serious condition called hemophag...

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

NCT ID: NCT06532773

This clinical trial is looking at a program called Nite2Day+, which aims to help patients with hematologic cancers (like leukemia and lymphoma) manage sleep problems and other symptoms such as fati...

Long-Term Follow-up Study

NCT ID: NCT05332054

CD45RA Depleted DLI After TCRα/β Depleted Haploidentical HCT

NCT ID: NCT05943067

This clinical trial is investigating a new treatment approach for patients with certain blood cancers, known as hematologic malignancies, who are in remission or have stable disease. The trial focu...

VitalTraq for the Detection of CRS

NCT ID: NCT06415656

This clinical trial is looking at two devices that help monitor important health signs in patients with blood cancers who are receiving specific types of treatments called CAR-T therapy or BiTE pro...

Reduced Intensity Fludarabine and TBI Prior to Haplo-Identical Transplantation

NCT ID: NCT05417971

This clinical trial is studying a new treatment approach for patients with blood cancers, known as hematologic malignancies. The treatment involves a reduced intensity transplant using a combinatio...

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

NCT ID: NCT06462365

This clinical trial is studying a new treatment called TRX-103 for patients with certain blood cancers, like Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia, who are getting a special type ...

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

NCT ID: NCT06082947

This clinical trial is studying a new approach for children and young adults with blood cancers who need a stem cell transplant but don't have a matched sibling donor. The researchers are using a s...

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT ID: NCT06131801

This clinical trial is studying how well venetoclax, a medication used to treat certain types of blood cancers like leukemia and lymphoma, works when the tablets are crushed and dissolved in liquid...