Clinical Trials for Locally Advanced Breast Cancer

Find clinical trials for locally advanced breast cancer. Discover research opportunities and treatment options in your area.

19 Active Trials Found

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT ID: NCT01042379

The I-SPY Trial is a research study aimed at finding out which new medications work best for different types of breast cancer. The goal is to personalize treatment by looking at how tumors respond ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Los Angeles, California, United States +35 more

A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

NCT ID: NCT06827236

This clinical trial is studying a new combination treatment for patients with advanced breast cancer, specifically looking at two investigational drugs called BNT323 and BNT327. The goal is to find...

Recruiting

Phase: PHASE1 Type: interventional Locations: Port Saint Lucie, Florida, United States, Huizhou, , China +2 more

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

NCT ID: NCT06449222

This clinical trial is investigating a new treatment called BNT327 for patients with locally advanced or metastatic triple-negative breast cancer, a type of breast cancer that does not respond to s...

Recruiting

Phase: PHASE2 Type: interventional Locations: Detroit, Michigan, United States, Westmead, New South Wales, Australia +69 more

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

NCT ID: NCT04360941

The PAveMenT clinical trial is studying a combination of two medications, palbociclib and avelumab, to find out the safest doses and treatment schedule for patients with a specific type of breast c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Sheffield, , United Kingdom, Glasgow, , United Kingdom +9 more

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer

NCT ID: NCT03255577

This clinical trial is exploring how well a procedure called sentinel lymph node biopsy (SLNB) can find any remaining cancer cells in women who have received treatment for locally advanced breast c...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States, Commack, New York, United States +6 more

A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

NCT ID: NCT07024173

This clinical trial is studying a new treatment called HRS-8080 for women with locally advanced or metastatic breast cancer, which means the cancer has spread beyond the breast or is difficult to r...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Guangzhou, , China, Changsha, Hunan, China

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

NCT ID: NCT06727773

This clinical trial is looking at how a medication called memantine, combined with an exercise program called Get Real & Heel, can help improve thinking and memory skills in women with breast cance...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chapel Hill, North Carolina, United States

A Phase I Clinical Trial of FWD1802 in Patients With ER+/HER2- BC.

NCT ID: NCT06064812

This clinical trial is studying a new treatment called FWD1802 for women with a specific type of breast cancer known as ER+/HER2- breast cancer that cannot be removed by surgery. The trial aims to ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

NCT ID: NCT06246968

This clinical trial is looking at the use of a medication called pembrolizumab, combined with a treatment called cryoablation, for people with advanced types of breast cancer, especially those with...

Recruiting

Phase: PHASE1 Type: interventional Locations: Middletown, New Jersey, United States, Montvale, New Jersey, United States +5 more

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

NCT ID: NCT05582499

This clinical trial, based at Fudan University Shanghai Cancer Center, is investigating new targeted therapies for women with operable breast cancer, specifically those with early-stage or locally ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

To Evaluate the Efficacy and Safety of Ipsilateral Supraclavicular Lymph Node Dissection for Breast Cancer Patients

NCT ID: NCT06605521

This clinical trial is looking at a specific surgery called ipsilateral supraclavicular lymph node dissection for women with locally advanced breast cancer. The goal is to find out if this surgery ...

Recruiting

Type: observational Locations: Zhengzhou, Henan, China, Zhengzhou, Henan, China

Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer

NCT ID: NCT06220214

This clinical trial is looking at new ways to monitor how well chemotherapy is working for women with early stage breast cancer. Specifically, the study is comparing a special type of mammogram tha...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Stony Brook, New York, United States

Breast Cancer Exercise Intervention Study

NCT ID: NCT05957068

The Breast Cancer Exercise Intervention Study is looking at how a structured exercise program can help women with early-stage and locally advanced breast cancer. This program lasts for 24 weeks and...

Recruiting

Phase: NA Type: interventional Locations: Singapore, , Singapore, Singapore, , Singapore +1 more

Predicting Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

NCT ID: NCT06499168

This clinical trial is investigating how well a specific marker called CD10 can help predict how patients with locally advanced breast cancer will respond to neoadjuvant chemotherapy, which is trea...

Not yet recruiting

Type: observational

Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma Patients

NCT ID: NCT03924466

This clinical trial is investigating a new imaging technique using a special substance called 68GaNOTA-Anti-HER2 VHH1 to help doctors see and measure tumors in patients with certain types of cancer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Brussels, Brussel, Belgium

Influence of Intermittent Fasting on Locally Advanced Breast Cancer Patients

NCT ID: NCT06174259

This clinical trial is studying the effects of intermittent fasting on women with locally advanced breast cancer who are about to start a specific type of chemotherapy called neoadjuvant chemothera...

Recruiting

Phase: NA Type: interventional Locations: Shibīn Al Kawm, Menoufia, Egypt

Adjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer

NCT ID: NCT04254263

This clinical trial is studying a medication called pyrotinib to see if it can help reduce the chances of breast cancer coming back in women who have already received treatment. Specifically, it fo...

Recruiting

Phase: PHASE3 Type: interventional Locations: Shanghai, Shanghai, China

The Choice of Treatment Methods and Efficacy of LABC

NCT ID: NCT06080620

This clinical trial is exploring the best way to treat locally advanced breast cancer, a type of breast cancer that has spread but is still contained in the breast area. The researchers want to fin...

Recruiting

Phase: NA Type: interventional Locations: Beijing, , China

Select the Appropriate Population for Adding CDK4/6i to Neoadjuvant Endocrine Therapy

NCT ID: NCT05809024

This clinical trial is looking to find out which women with locally advanced, hormone receptor positive, HER2-negative breast cancer may benefit from adding a specific type of medication called CDK...

Recruiting

Phase: PHASE4 Type: interventional Locations: Jinan, Shandong, China

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