Clinical Trials for Malignant Solid Neoplasm

Find clinical trials for malignant solid neoplasm. Discover research opportunities and treatment options in your area.

113 Active Trials Found

Showing 113 trials on this page

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National Cancer Institute "Cancer Moonshot Biobank"

NCT ID: NCT04314401

The "Cancer Moonshot Biobank" is a clinical trial that aims to gather blood and tissue samples from patients diagnosed with various types of cancer, including advanced stages of breast cancer, lung...

Recruiting

Type: observational Locations: Des Moines, Iowa, United States, Scarborough, Maine, United States +176 more

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

NCT ID: NCT05554367

The clinical trial titled "Palbociclib and Binimetinib in RAS-Mutant Cancers" is investigating how effective a combination of two medications, palbociclib and binimetinib, can be for treating certa...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Durham, North Carolina, United States +292 more

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

NCT ID: NCT06126276

This clinical trial is investigating the effects of two treatments for patients with certain types of cancer known as HER2 positive solid tumors. The study compares a medication called neratinib to...

Recruiting

Phase: PHASE2 Type: interventional Locations: Durham, North Carolina, United States, Bethesda, Maryland, United States +158 more

Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

NCT ID: NCT05286801

This clinical trial is focused on studying two medications, tiragolumab and atezolizumab, to see how well they work in treating certain types of aggressive tumors that have either returned after tr...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Durham, North Carolina, United States +41 more

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

NCT ID: NCT04871542

This clinical trial is studying how different factors, like a person's age, gender, and existing health conditions, can influence the likelihood of experiencing side effects from immunotherapy trea...

Recruiting

Type: observational Locations: Ames, Iowa, United States, Ames, Iowa, United States +4 more

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

NCT ID: NCT00991094

This clinical trial is designed to gather important information about the side effects of proton therapy, a type of radiation treatment, in patients with various cancers including breast, lung, and...

Recruiting

Type: observational Locations: Houston, Texas, United States

A Study to Evaluate Multicancer Detection (MCD) Tests and Their Impact on Participant Health and Cancer Screening, The Vanguard Study

NCT ID: NCT06995898

The Vanguard Study is a clinical trial that aims to evaluate two new blood tests, called Shield and Avantect, which are designed to detect multiple types of cancer early. This study focuses on adul...

Not yet recruiting

Phase: NA Type: interventional

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

NCT ID: NCT04407247

This clinical trial is exploring how effective and safe two treatments, infliximab and vedolizumab, are for patients experiencing inflammation of the colon (called colitis) due to immune checkpoint...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

NCT ID: NCT06184321

This clinical trial is studying whether a medication called alteplase can help patients with a specific type of fluid buildup in the chest, known as malignant pleural effusion, which can cause brea...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Houston, Texas, United States

Expressive Writing for the Management of Stress in Cancer Survivors

NCT ID: NCT04776941

This clinical trial is exploring how expressive writing can help manage stress for people who have survived cancer. Many cancer survivors face increased stress due to worries about family, jobs, fi...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines

NCT ID: NCT02962661

This clinical trial is investigating whether special cells derived from donor bone marrow, called mesenchymal stem cells, can help improve heart function and control symptoms of heart failure in pa...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

NCT ID: NCT04745910

This clinical trial is looking at a medication called pegloticase to see if it can help lower high levels of uric acid in patients who have tumor lysis syndrome, a condition that can occur after ca...

Recruiting

Phase: PHASE4 Type: interventional Locations: Houston, Texas, United States

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

NCT ID: NCT03819296

This clinical trial is examining how the gut microbiome, which is the collection of bacteria and other microorganisms in our digestive system, affects gastrointestinal (GI) problems caused by certa...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Access to Genetic Testing in Underserved Patients With Cancer

NCT ID: NCT06422455

This clinical trial is looking at how patients with cancer can get information about genetic testing. The study compares two ways of providing this information: one group of patients will receive g...

Recruiting

Phase: NA Type: interventional Locations: Rochester, New York, United States, Los Angeles, California, United States

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

NCT ID: NCT06279013

This clinical trial is looking at different ways to help people manage symptoms and feelings of distress, like anxiety and depression, while they are undergoing oral cancer treatment. The study com...

Recruiting

Phase: NA Type: interventional Locations: Urbana, Illinois, United States, Anderson, South Carolina, United States +27 more

Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning

NCT ID: NCT04515810

This clinical trial is studying a new mobile app called Planning Advance Care Together (PACT) to help people with cancer have important conversations about their future healthcare wishes. The app a...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States, New York, New York, United States +2 more

RefleXion PET/CT Imaging Performance in Patients With Various Malignancies

NCT ID: NCT05844306

This clinical trial is studying a new imaging system called the RefleXion Medical Radiotherapy System (RMRS) to see how well it works compared to the standard imaging method known as PET-CT scans i...

Recruiting

Phase: NA Type: interventional Locations: Duarte, California, United States

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

NCT ID: NCT06771739

The PAYMENT Trial is a clinical study designed to see if giving early-stage cancer patients cash payments can help them handle the financial stress that often comes with a cancer diagnosis. Many pa...

Not yet recruiting

Phase: NA Type: interventional Locations: Vancouver, Washington, United States, Bellingham, Washington, United States

Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method

NCT ID: NCT05054413

This clinical trial is focused on improving the care of patients with prostate cancer by gathering expert opinions on the most important information that should be included in medical reports. Usin...

Recruiting

Type: observational Locations: Houston, Texas, United States

Positive Activities Intervention to Improve Quality of Life in Collectivist Culture Cancer Patients and Their Caregivers

NCT ID: NCT04810052

This clinical trial is exploring ways to improve the quality of life for cancer patients and their caregivers from collectivist cultures, such as Latino, Asian American, and African American commun...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

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