Clinical Trials for Mitochondrial Diseases

Evaluate the Safety and Therapeutic Effects of a Single Intravenous Infusion (IV) of Autologous CD34+ Cells Enriched With Allogenic Placenta-derived Mitochondria in Patients With a Diagnosis of Pearson Syndrome (PS)

NCT ID: NCT06017869

The clinical trial titled "Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-201 in Pediatric Patients With Pearson Syndrome" is investigating a new treatment for children with ...

Global Registry and Natural History Study for Mitochondrial Disorders

NCT ID: NCT05554835

The Global Registry and Natural History Study for Mitochondrial Disorders is a research project aimed at understanding various mitochondrial diseases, which are conditions that affect how our cells...

Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome

NCT ID: NCT04802707

This clinical trial is studying a potential new treatment for a group of rare genetic disorders called Mitochondrial Depletion Syndromes (MDS). These conditions happen when there is a serious short...

Enhancement of Quality of Work And Life

NCT ID: NCT06573866

This clinical trial, called "Enhancement of Quality of Work And Life," is exploring ways to help people with certain movement disorders—like Parkinson's Disease and ataxia—stay employed and improve...

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

NCT ID: NCT01793168

The Coordination of Rare Diseases at Sanford (CoRDS) is a clinical trial aimed at creating a large, centralized registry for individuals affected by rare diseases. This registry helps connect patie...

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

NCT ID: NCT06451757

The KHENERFIN Study is a clinical trial aimed at testing a medication called sonlicromanol for people with certain types of mitochondrial diseases, which are conditions that affect the body's energ...

Combating the Diagnostic Impasse in Mitochondrial Diseases: a Transcriptomic Approach in Fibroblasts and Blood Cells

NCT ID: NCT06621732

This clinical trial is focused on improving the diagnosis of mitochondrial diseases, which are conditions that affect how our cells produce energy. Even with advanced genetic testing techniques, ab...

MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases

NCT ID: NCT04920812

The MITOMICS trial is studying how to better diagnose mitochondrial diseases, which affect how our cells produce energy. Specifically, the researchers want to find out which results from a type of ...

CrCest Study in Primary Mitochondrial Disease

NCT ID: NCT04734626

Validation of Oxygen Nanosensor in Mitochondrial Myopathy

NCT ID: NCT04086329

This clinical trial is studying a special device called an electrochemical oxygen nanosensor, which is designed to measure how well mitochondria (the energy-producing parts of our cells) are functi...

Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

NCT ID: NCT04322734

This clinical trial is studying how certain biological markers in the body relate to neurological and developmental disorders like Autism Spectrum Disorder (ASD), epilepsy, brain tumors, and other ...

Applying pGz in Mitochondrial Disease

NCT ID: NCT05569122

This clinical trial, titled "Applying pGz in Mitochondrial Disease," is exploring new ways to help people with mitochondrial diseases, specifically mitochondrial myopathies. The study will compare ...

Digital Health Technology for People With Mitochondrial Disease

NCT ID: NCT06535646

This clinical trial is studying how digital health technology can help people with mitochondrial diseases (MD) improve their exercise habits. Many individuals with MD struggle to stay active, and f...

Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases

NCT ID: NCT06450964

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

NCT ID: NCT01694940

The North American Mitochondrial Disease Consortium (NAMDC) is conducting a study to better understand mitochondrial disorders, which are conditions that affect how our cells produce energy. They a...

The Natural History of Mitochondrial Diseases

NCT ID: NCT06504433

This clinical trial, titled "The Natural History of Mitochondrial Diseases," is focused on understanding mitochondrial diseases, which are a group of genetic disorders that affect how cells produce...

The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling

NCT ID: NCT05483738

This clinical trial is studying how problems with tiny parts of cells called mitochondria, which help produce energy, might affect bone health. Researchers want to find out if these issues change h...

Genetic Diagnosis in Inborn Errors of Metabolism

NCT ID: NCT06376279

Red Light Ptosis Proof-of-Concept

NCT ID: NCT06292182

This clinical trial, called the Red Light Ptosis Proof-of-Concept, is testing a new treatment aimed at helping children and young people with droopy eyelids (called ptosis) and eye movement issues,...

Peripheral Vascular REactivity and Muscular Oxygenation in Diabetes Mellitus

NCT ID: NCT04226820

This clinical trial is investigating how well blood vessels and muscles work together to use oxygen in people with diabetes. In diabetes, high blood sugar can damage blood vessels, which may reduce...