Clinical Trials for Multiple System Atrophy

A Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy (MSA): A Safety and Efficacy Study

NCT ID: NCT06568237

This clinical trial is studying a new medication called TEV-56286 to see if it can help relieve symptoms in adults with Multiple System Atrophy (MSA), a rare and serious condition that affects move...

A Trial of Lu AF82422 in Participants With Multiple System Atrophy (MSA)

NCT ID: NCT06706622

This clinical trial is studying a new treatment called Lu AF82422 for people with Multiple System Atrophy (MSA), a rare neurological condition that affects movement and balance. The main goal of th...

hUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases

NCT ID: NCT06607900

This clinical trial, called HUC-MSC-sEV-001, is looking at a new treatment using nasal drops made from special cells derived from human umbilical cords. The goal is to see if these drops are safe a...

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

NCT ID: NCT06848231

This clinical trial is studying a new treatment called YA-101 for people with Multiple System Atrophy (MSA), a rare and progressive neurological condition affecting movement and coordination. The t...

Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy

NCT ID: NCT05167721

This clinical trial is investigating a potential new treatment for Multiple System Atrophy (MSA), a rare and serious neurological condition that currently has no available treatments to slow its pr...

Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

NCT ID: NCT04782830

This clinical trial is studying a new way to measure how well treatments work for people with neurogenic orthostatic hypotension, a condition where standing up can cause a significant drop in blood...

Efficacy and Safety of Bilateral Cervical Lymphatic-Venous Anastomosis in the Treatment of Multiple System Atrophy

NCT ID: NCT07036939

This clinical trial is studying a new surgical procedure called bilateral cervical lymphatic-venous anastomosis (LVA) to see if it can help people with Multiple System Atrophy (MSA), a rare and ser...

Natural History Study of Synucleinopathies

NCT ID: NCT01799915

This clinical trial, called the Natural History Study of Synucleinopathies, is looking into a group of rare neurological disorders that affect movement and cognition due to the buildup of a protein...

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

NCT ID: NCT04620382

This clinical trial is studying how two different treatments—midodrine, a medication, and abdominal compression, which involves wearing a special device that applies pressure to the abdomen—affect ...

Gait Analysis in Neurological Disease

NCT ID: NCT02994719

This clinical trial, titled "Gait Analysis in Neurological Disease," is studying how walking speed and patterns can be measured in people with various neurological conditions, especially those with...

Safety, Tolerability, and Pharmacokinetics of Exidavnemab in Patients With Parkinson's Disease and Patients With Multiple System Atrophy

NCT ID: NCT06671938

This clinical trial is studying a new medication called exidavnemab to see if it's safe and well-tolerated in people with Parkinson's disease. The trial is currently recruiting participants aged 40...

Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

NCT ID: NCT02429557

This clinical trial is studying how wearing special compression garments on the abdomen can help improve blood pressure and reduce symptoms in patients with a condition called orthostatic hypotensi...

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

NCT ID: NCT01793168

The Coordination of Rare Diseases at Sanford (CoRDS) is a clinical trial aimed at creating a large, centralized registry for individuals affected by rare diseases. This registry helps connect patie...

Comprehensive Swallowing Rehabilitation in Patients With MSA

NCT ID: NCT04782284

This clinical trial is looking at how a special swallowing therapy can help people with Multiple System Atrophy (MSA), a condition that affects movement and can cause difficulties with swallowing. ...

Community Outreach for Palliative Engagement -- Parkinson Disease

NCT ID: NCT05222386

This clinical trial, called "Community Outreach for Palliative Engagement -- Parkinson Disease," is looking to understand how effective palliative care training for community doctors and telemedici...

The Swedish BioFINDER 2 Study

NCT ID: NCT03174938

The Swedish BioFINDER 2 study is a research project aimed at understanding different types of dementia, including Alzheimer's disease and related conditions. This study builds on previous research ...

Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

NCT ID: NCT04706234

This clinical trial is studying how swallowing and laryngeal (throat) function are affected in patients with certain neurological conditions, specifically Multiple System Atrophy (MSA), Parkinson's...

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

NCT ID: NCT06683365

This clinical trial is exploring a new treatment for people with Parkinson's disease or Multiple System Atrophy, which are conditions that affect movement and can cause various symptoms. The study ...

A Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)

NCT ID: NCT06868628

This clinical trial is investigating a medication called Foralumab, which is delivered through the nose, to see if it can help patients with Multiple System Atrophy (MSA). MSA is a rare and serious...

Parkinson Atypical Rating of Oculometric Patterns Evaluated Routinely

NCT ID: NCT06597071