Clinical Trials for Opioid Dependence

Find clinical trials for opioid dependence. Discover research opportunities and treatment options in your area.

20 Active Trials Found

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Neuromodulation and Cognitive Training in Opioid Use Disorder

NCT ID: NCT03773523

This clinical trial is looking at new ways to help people struggling with opioid use disorder (OUD), which is a serious condition where individuals have a strong dependence on opioids, like prescri...

Recruiting

Phase: NA Type: interventional Locations: Minneapolis, Minnesota, United States

VK4-116 Phase I Study With Food-Effect

NCT ID: NCT06808932

This clinical trial, called VK4-116 Phase I Study, is exploring a new medication designed to help with opioid dependence and opioid use disorder. The main goal is to test the safety and how well th...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Overland Park, Kansas, United States

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

NCT ID: NCT05603702

The STTEPP clinical trial is studying the safety and tolerability of a medication called lacosamide in patients who have chronic abdominal pain due to a condition known as chronic pancreatitis. Thi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Columbus, Ohio, United States +3 more

Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

NCT ID: NCT06949826

This clinical trial is studying the use of buprenorphine, a type of pain medication, as a way to manage pain after ankle fracture surgery. Traditional pain medications like oxycodone can be very ad...

Recruiting

Phase: PHASE4 Type: interventional Locations: Saint Louis, Missouri, United States

Better Options for Chronic Cancer Pain

NCT ID: NCT06574009

This clinical trial, titled "Better Options for Chronic Cancer Pain," is designed to find safer alternatives for cancer survivors who are still using opioids to manage their chronic pain after comp...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Indianapolis, Indiana, United States, Ann Arbor, Michigan, United States

fMRI and Opioid Abstinence

NCT ID: NCT06651333

This clinical trial is studying how certain brain activity patterns may relate to the risk of relapse in people recovering from opioid dependence. The researchers are particularly interested in tho...

Recruiting

Type: observational Locations: New Haven, Connecticut, United States

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care

NCT ID: NCT06837662

The MOUD Plus Pilot trial is exploring whether adding counseling and peer support to regular medication treatment can help people with opioid use disorder (OUD) stay engaged in their care and conti...

Not yet recruiting

Phase: NA Type: interventional Locations: Portland, Oregon, United States

Measuring Acute Drug Demand in Humans

NCT ID: NCT05829655

This clinical trial is investigating whether a medication called suvorexant can help reduce the craving for and use of various drugs in people who have Opioid Use Disorder (OUD). The research aims ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Baltimore, Maryland, United States

Young Houston Emergency Opioid Engagement System

NCT ID: NCT04811014

The Young Houston Emergency Opioid Engagement System (Young HEROES) is a clinical trial aimed at helping young people who are struggling with opioid use, such as those who might be dependent on or ...

Recruiting

Phase: PHASE4 Type: interventional Locations: Houston, Texas, United States

Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder

NCT ID: NCT04454411

This clinical trial, titled "Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder," aims to understand how certain medications help prevent relapse in people struggling with opioid addiction....

Not yet recruiting

Phase: PHASE2 Type: interventional

A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy Male Subjects.

NCT ID: NCT05620940

This clinical trial is looking at two investigational drugs, IVL3004 and IVL4002, to understand how they are processed in the body, as well as their safety and tolerability. The study is focused on...

Recruiting

Phase: PHASE1 Type: interventional Locations: Herston, Queensland, Australia

An Innovative Intervention for OUD Treatment

NCT ID: NCT04325659

This clinical trial is studying an innovative medical device called the Bridge Device (BD), which is designed to help people with Opioid Use Disorder (OUD). The goal is to see how effective the BD ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Baltimore, Maryland, United States

Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB

NCT ID: NCT06129916

This clinical trial is focused on evaluating a new treatment option called long-acting depot buprenorphine (LADB) for people who are dependent on opioids, particularly those who inject drugs. The s...

Not yet recruiting

Type: observational

DE-eSCALation of Opioids Post-surgical dischargE

NCT ID: NCT06396663

The DE-eSCALation of Opioids Post-surgical dischargE study, also known as the Descale Study, is looking into how opioids (strong pain medications) are prescribed to patients after surgery and how t...

Recruiting

Phase: NA Type: interventional Locations: Faversham, Kent, United Kingdom

A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders.

NCT ID: NCT05995873

This clinical trial is studying a new treatment for people struggling with opioid addiction. The researchers want to see if a special type of light therapy, which involves shining near-infrared lig...

Recruiting

Phase: NA Type: interventional Locations: Newton Highlands, Massachusetts, United States

Reducing Opioid Use for Chronic Pain Patients Following Surgery

NCT ID: NCT03675386

This clinical trial, called the Transitional Pain Service Program (TPSP), is designed to help patients with chronic pain reduce their use of opioids after surgery. Opioids are strong pain medicatio...

Recruiting

Phase: NA Type: interventional Locations: Toronto, Ontario, Canada

Gut Microbiota Dysbiosis in Opioid Use Disorders: Implications for Clinical Symptoms and Relapse Rate.

NCT ID: NCT06231849

This clinical trial is looking at how the bacteria in the gut (called gut microbiota) may affect people who are dealing with opioid use disorders. The researchers want to understand if the types an...

Not yet recruiting

Type: observational

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

NCT ID: NCT05585229

This clinical trial is exploring a new treatment approach that uses psilocybin, a natural substance found in certain mushrooms, combined with therapy to help people who are dependent on opioid medi...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Kelowna, British Columbia, Canada

Intervening With Opioid-Dependent MothersMothers and Infants

NCT ID: NCT04454645

This clinical trial is studying a special program called the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention. It aims to help mothers who are pregnant and dealing with opioid dep...

Recruiting

Phase: NA Type: interventional Locations: Newark, Delaware, United States

Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction

NCT ID: NCT03813095

This clinical trial is looking at a new medication called APH-1501 to see if it is safe and effective for people struggling with opioid addiction. The main goal is to find out how different doses o...

Not yet recruiting

Phase: PHASE2 Type: interventional

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