Clinical Trials for Opioid Use Disorder

Extended-release Buprenorphine as a Novel Low-dose Induction Strategy

NCT ID: NCT06441604

This clinical trial is looking at a new way to help people with opioid use disorder (OUD) by using a medication called extended-release buprenorphine (XR-BUP). The goal is to see if this low-dose t...

Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder

NCT ID: NCT06577454

This clinical trial is investigating how a type of brain stimulation called transcranial magnetic stimulation (TMS) might help people who use opioids, such as heroin or methadone, make better decis...

Disclosure Intervention for People in Treatment for Opioid Use Disorder

NCT ID: NCT06458985

This clinical trial is looking at a special program designed to help people in treatment for opioid use disorder. The main goal is to see if this program, which encourages people to share their exp...

An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)

NCT ID: NCT06576323

The SUPPORT trial is studying how to improve care for mothers dealing with opioid use disorder (OUD) and their newborns who may be experiencing neonatal abstinence syndrome (NAS). The goal is to cr...

High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)

NCT ID: NCT05589181

This clinical trial is studying the effects of a higher dose of buprenorphine (BUP) for treating opioid use disorder in patients who visit the emergency department. The goal is to see if starting t...

Workforce and System Change to Treat Adolescent Opioid Use Disorder Within Integrated Pediatric Primary Care

NCT ID: NCT06477848

Sublingual Buprenorphine Through Telemedicine vs In-Person Care as Usual

NCT ID: NCT05339256

This clinical trial is studying the effectiveness of a medication called sublingual buprenorphine for treating opioid use disorder (OUD). The trial will compare two ways of receiving treatment: one...

Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

NCT ID: NCT06157840

This clinical trial is focused on developing a mobile health application designed to help people who are struggling with sleep problems, especially those undergoing treatment for opioid use disorde...

Behavioral Effects of Drugs Inpatient 44 Neurobehavioral Mechanisms of Opioid Choice

NCT ID: NCT06312657

This clinical trial is studying how people with opioid use disorder make decisions when it comes to drug use. Researchers want to understand the brain processes involved in choosing opioids and how...

Autobiographical Memory in Opioid Use Disorder

NCT ID: NCT06643988

This clinical trial is aimed at understanding how memory works in people with opioid use disorder (OUD) and whether memory training can help improve their symptoms and quality of life. Participants...

tAN for PTSD and OUD in Buprenorphine Therapy

NCT ID: NCT06130501

This clinical trial is exploring a new treatment option for people who have both Posttraumatic Stress Disorder (PTSD) and Opioid Use Disorder (OUD) and are starting buprenorphine therapy, which is ...

Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

NCT ID: NCT06999811

This clinical trial is exploring how effective a new type of therapy combined with technology is for pregnant individuals who are being treated for opioid use disorder with a medication called bupr...

A Study to Test Whether BI 1356225 Improves Impulsive Behavior in Men With Opioid Use Disorder Who Are Taking Buprenorphine

NCT ID: NCT06628622

This clinical trial is studying a new medicine called BI 1356225 to see if it helps improve impulsive behavior in men aged 18 to 65 who have opioid use disorder and are currently taking buprenorphi...

Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders

NCT ID: NCT06545071

This clinical trial is studying a new digital program called NEAT-O, which is designed to help people struggling with opioid use disorder (OUD) who also have anxiety or depression. The goal of the ...

A Phase 1b Study Comparing the Pharmacokinetics and Safety of Low- and High-Dose BIOPIN Naltrexone Implants With Monthly Vivitrol Injections in Healthy Volunteers Over 12 Months

NCT ID: NCT07064564

This clinical trial is testing a new type of treatment for opioid use disorder, which is a condition where people struggle with dependence on opioids. The study is comparing a small implant called ...

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment

NCT ID: NCT06367387

This clinical trial is focused on improving the treatment of chronic pain for individuals who are using buprenorphine, a medication often prescribed for opioid addiction. The study is testing two m...

Mobile Mindfulness Training (mMT) for People in Medication Treatment of Opioid Use Disorder (MOUD)

NCT ID: NCT06857968

This clinical trial, called the Pilot Mobile Mindfulness Training (mMT) for People in Medication Treatment of Opioid Use Disorder, is exploring whether using a mobile app for mindfulness training c...

Psilocybin for Opioid Use Disorder (OUD)

NCT ID: NCT06796062

This clinical trial is studying the effects of psilocybin, a psychedelic substance, to see if it can help people with Opioid Use Disorder (OUD) who are still using illicit opioids despite being on ...

Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder

NCT ID: NCT06487533

This clinical trial is studying how the body reacts during opioid withdrawal and cravings in people who have an opioid use disorder. Researchers want to understand changes in certain body signals t...

Social Functioning in Opioid Use Disorder

NCT ID: NCT07044466

This clinical trial is studying how social relationships and interactions affect people with opioid use disorder (OUD), a condition where someone struggles with using opioids like prescription pain...