Clinical Trials for Oropharyngeal Squamous Cell Carcinoma

Find clinical trials for oropharyngeal squamous cell carcinoma. Discover research opportunities and treatment options in your area.

18 Active Trials Found

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

NCT ID: NCT06532279

This clinical trial is studying whether adding a drug called BMX-001 to the usual treatment for head and neck cancer can help reduce a painful side effect called oral mucositis, which causes mouth ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Oklahoma City, Oklahoma, United States +32 more

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

NCT ID: NCT05268614

This clinical trial is investigating a new approach to treating oropharyngeal squamous cell carcinoma, a type of throat cancer, by using less intense radiation and chemotherapy for certain patients...

Recruiting

Phase: PHASE2 Type: interventional Locations: Charleston, South Carolina, United States, Gainesville, Florida, United States +1 more

Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer

NCT ID: NCT06362421

This clinical trial is investigating whether saliva and oral swab samples can effectively detect human papillomavirus (HPV) in patients with a specific type of throat cancer called oropharyngeal sq...

Not yet recruiting

Type: observational Locations: High Point, North Carolina, United States, Winston Salem, North Carolina, United States

People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity

NCT ID: NCT06055868

This clinical trial is exploring the experiences of people living with HIV who may also face oral and throat cancers. The study aims to understand the challenges and advantages these individuals en...

Recruiting

Type: observational Locations: San Francisco, California, United States

The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan

NCT ID: NCT05522881

This clinical trial, known as the Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan, is investigating genetic changes in a type of throat cancer called oropharyngeal squamous ...

Recruiting

Type: observational Locations: Kaohsiung, , Taiwan, Taipei, , Taiwan +5 more

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

NCT ID: NCT04564989

This clinical trial is studying a type of throat cancer known as HPV-associated oropharyngeal squamous cell carcinoma (OPSCC). The main goal is to see if doctors can predict whether this cancer wil...

Recruiting

Type: observational Locations: Rochester, Minnesota, United States, Chapel Hill, North Carolina, United States +1 more

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

NCT ID: NCT06662058

This clinical trial is looking at how offering hearing tests close to home or through remote options can help monitor hearing loss in patients with certain types of head and neck cancers who are re...

Recruiting

Phase: NA Type: interventional Locations: Atlanta, Georgia, United States

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

NCT ID: NCT06914999

This clinical trial is looking at a new type of imaging test called F-18 NaF PET/CT, which may help doctors better assess how radiation therapy affects blood vessels in the neck of patients with he...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Atlanta, Georgia, United States

The Role of Circulating Tumour DNA in Head and Neck Cancer

NCT ID: NCT05539638

This clinical trial is studying the use of a new blood test to help diagnose and monitor oropharyngeal squamous cell carcinoma (OPSCC), a type of throat cancer linked to the human papillomavirus (H...

Recruiting

Type: observational Locations: Glasgow, , United Kingdom, Dundee, , United Kingdom +4 more

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

NCT ID: NCT06323460

This clinical trial is looking at how well a new approach to radiation therapy works for patients with a specific type of throat cancer linked to the human papillomavirus (HPV). Researchers want to...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States

Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma

NCT ID: NCT04852328

This clinical trial is investigating a new treatment called CUE-101 for patients with a specific type of throat cancer known as oropharyngeal squamous cell carcinoma, particularly those who are pos...

Recruiting

Phase: PHASE2 Type: interventional Locations: Saint Louis, Missouri, United States

Validity of Viome's Oral/throat Cancer Test

NCT ID: NCT06174428

This clinical trial is studying the effectiveness of a new test developed by Viome to help detect oral and throat cancers, specifically two types called oral squamous cell carcinoma (OSCC) and orop...

Recruiting

Type: observational Locations: St. Louis, Missouri, United States, Memphis, Tennessee, United States

Oropharynx (OPX) Biomarker Trial

NCT ID: NCT06356272

The Oropharynx Biomarker Trial is a research study focused on finding a specific biological marker linked to certain types of throat cancer caused by the human papillomavirus (HPV). The goal is to ...

Recruiting

Type: observational Locations: Rochester, Minnesota, United States

Neoadjuvant Sintilimab Combined With Reduction of Cycles of Chemotherapy in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-002)

NCT ID: NCT05098119

This clinical trial, called OOC-002, is investigating a treatment approach for patients with certain types of mouth and throat cancers, specifically oral cavity and oropharyngeal squamous cell carc...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers

NCT ID: NCT05582590

This clinical trial is exploring a new treatment for patients with HPV-related oropharyngeal cancers that have not responded to standard therapies. The study is testing a product made from the pati...

Not yet recruiting

Phase: PHASE1 Type: interventional

Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.

NCT ID: NCT05333523

The PRIMO Study is a clinical trial designed to explore a personalized approach to treating certain types of throat cancers, specifically cancers of the oropharynx, larynx, and hypopharynx. The tri...

Recruiting

Phase: PHASE3 Type: interventional Locations: Leiden, , Netherlands, Nijmegen, , Netherlands +6 more

A New Mutational and Epigenetic Signature to Predict Early OPSCC Relapse

NCT ID: NCT06138483

This clinical trial is studying a new way to identify oropharyngeal squamous cell carcinoma (OPSCC) patients who are at high risk for their cancer coming back early. The researchers are looking at ...

Recruiting

Type: observational Locations: Aviano, , Italy, Belluno, , Italy +3 more

Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

NCT ID: NCT04220749

This clinical trial is comparing two different treatments for patients with early-stage oropharyngeal squamous cell carcinoma, which is a type of head and neck cancer that is not linked to the HPV ...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, Ontario, Canada

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