A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

NCT ID: NCT06778863

This clinical trial is studying a new treatment called CLSP-1025 for adults with certain types of solid tumors that have a specific genetic mutation known as p53 R175H. These tumors can include adv...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, New York, New York, United States +8 more

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

NCT ID: NCT06503146

This clinical trial is studying a new imaging method using a special substance called 18F-FAPI-74 to help detect certain types of cancer more effectively. The goal is to find out if this new tracer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Relacorilant in Combination With Nab-paclitaxel and Bevacizumab in Advanced, Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

NCT ID: NCT06906341

This clinical trial is testing a new treatment approach for women with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. The study will examine how effective and safe a ...

Recruiting

Phase: PHASE2 Type: interventional Locations: San Francisco, California, United States, Centerville, Ohio, United States +21 more

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

NCT ID: NCT01441089

This clinical trial is studying how certain genes may affect the way people with cancer respond to treatment. Researchers believe that some genes can influence the side effects of treatment and how...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

NCT ID: NCT06824467

This clinical trial is studying a new treatment called sacituzumab tirumotecan (MK-2870) for women with platinum-sensitive recurrent ovarian cancer. The trial aims to find out if this treatment is ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Goyang Si, Kyonggi Do, Korea, Republic Of, Omaha, Nebraska, United States +27 more

A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer

NCT ID: NCT07030907

This clinical trial is studying a new treatment called OPB-101 for women with ovarian cancer that has come back and does not respond to platinum-based chemotherapy, a common cancer treatment. The m...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Minneapolis, Minnesota, United States, Houston, Texas, United States +1 more

Combined Program of Supervised Physical Exercise and Nutritional Counseling in Ovarian Cancer Patients on Frontline Maintenance Treatment With PARP Inhibitors

NCT ID: NCT06139783

This clinical trial is exploring the effects of a combined program of supervised physical exercise and nutritional counseling for women with ovarian cancer who are receiving a specific type of trea...

Not yet recruiting

Phase: NA Type: interventional Locations: Madrid, , Spain, Madrid, , Spain +2 more

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT ID: NCT04981119

This clinical trial is exploring how often certain solid tumors, like colorectal cancer and lung cancer, lose a specific gene marker called Human Leukocyte Antigen (HLA) and how this loss might aff...

Recruiting

Type: observational Locations: Palo Alto, California, United States, Rochester, Minnesota, United States +12 more

Minimally Invasive Interval Debulking Surgery in Advanced Ovarian Cancer

NCT ID: NCT07031908

This clinical trial is studying a less invasive type of surgery for women with advanced ovarian cancer who have already received chemotherapy. Usually, women with this condition have chemotherapy f...

Not yet recruiting

Type: observational Locations: Roma, , Italy

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT ID: NCT06238479

This clinical trial is investigating a new drug called LY4101174 to see if it is safe and effective for people with advanced solid tumors that have come back or spread to other parts of the body. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Boston, Massachusetts, United States +34 more

SLV-154 Treatment of Metastatic Solid Tumors

NCT ID: NCT06771219

This clinical trial is studying a new treatment called SLV-154 for patients with certain types of metastatic solid tumors, which are cancers that have spread from their original site to other parts...

Recruiting

Phase: PHASE1 Type: interventional Locations: St. Louis, Missouri, United States, Saint Louis, Missouri, United States +2 more

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

NCT ID: NCT03556228

This clinical trial is studying a new medication called VMD-928, which is being tested for patients with certain types of advanced cancers and lymphomas that have not responded to standard treatmen...

Recruiting

Phase: PHASE1 Type: interventional Locations: Milwaukee, Wisconsin, United States, Duarte, California, United States +32 more

Proactive Immune Tolerance Induction in Chemotherapy for Gynecologic Cancer

NCT ID: NCT06977594

This clinical trial is studying a new approach to help women with ovarian, endometrial, or cervical cancer who are receiving chemotherapy. The researchers want to find out if a treatment called imm...

Not yet recruiting

Phase: NA Type: interventional Locations: Seoul, , Korea, Republic Of

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

NCT ID: NCT07029399

This clinical trial is testing a new medicine called NKT5097 in adults who have advanced or spreading solid tumors, including different types of breast, ovarian, and uterine cancers. The main goal ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Grand Rapids, Michigan, United States +2 more

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT ID: NCT05445778

The GLORIOSA clinical trial is studying a new treatment approach for patients with certain types of ovarian, fallopian tube, or peritoneal cancer who have responded well to previous platinum-based ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Columbus, Ohio, United States, Charlottesville, Virginia, United States +567 more

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

NCT ID: NCT05071937

The clinical trial titled "ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer" is studying a new combination of two medications, ZEN003694 and talazoparib, to see if they...

Recruiting

Phase: PHASE2 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

NCT ID: NCT06999187

This clinical trial is looking at a new treatment called DR-0202 for patients with certain types of advanced cancers, including triple-negative breast cancer and non-small cell lung cancer, among o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Denver, Colorado, United States +8 more

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

NCT ID: NCT07023627

This clinical trial is studying a new drug called INCB123667 for women with a type of ovarian cancer that has stopped responding to standard platinum-based chemotherapy. Specifically, it focuses on...

Not yet recruiting

Phase: PHASE2 Type: interventional

Fluzoparib+Bevacizumab/Dietary Intervention vs Fluzoparib Monotherapy as First-line Maintenance in HRD+/- Advanced Ovarian Cancer

NCT ID: NCT06954584

This clinical trial is investigating a combination treatment for advanced ovarian cancer, focusing on two groups of patients based on specific genetic characteristics. It aims to see if combining f...

Recruiting

Phase: PHASE3 Type: interventional Locations: Wuhan, Hubei, China

APG-2449 in Patients With Advanced Solid Tumors

NCT ID: NCT03917043

This clinical trial is studying a new drug called APG-2449, which is designed to treat patients with advanced solid tumors, including specific types of lung cancer, esophageal cancer, ovarian cance...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chengdu, Sichuan, China, Fuzhou, Fujian, China +8 more

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Clinical Trials for Ovarian Cancer

405 Active Trials Found

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Relacorilant in Combination With Nab-paclitaxel and Bevacizumab in Advanced, Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer

Combined Program of Supervised Physical Exercise and Nutritional Counseling in Ovarian Cancer Patients on Frontline Maintenance Treatment With PARP Inhibitors

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Minimally Invasive Interval Debulking Surgery in Advanced Ovarian Cancer

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

SLV-154 Treatment of Metastatic Solid Tumors

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Proactive Immune Tolerance Induction in Chemotherapy for Gynecologic Cancer

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Fluzoparib+Bevacizumab/Dietary Intervention vs Fluzoparib Monotherapy as First-line Maintenance in HRD+/- Advanced Ovarian Cancer

APG-2449 in Patients With Advanced Solid Tumors

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