Clinical Trials for Rectal Cancer

Find clinical trials for rectal cancer. Discover research opportunities and treatment options in your area.

233 Active Trials Found

Showing 233 trials on this page

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The Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery

NCT ID: NCT05651971

This clinical trial is studying the relationship between certain blood vessels in the abdomen during surgery for rectal cancer. Specifically, it focuses on measuring the distances between the left ...

Recruiting

Type: observational Locations: Xi'an, Shanxi, China

The First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard Therapy

NCT ID: NCT05640726

This clinical trial is looking at a new treatment approach for patients with rectal cancer that has spread to the liver and cannot be surgically removed. The study aims to see how effective and saf...

Not yet recruiting

Phase: PHASE2 Type: interventional

ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer

NCT ID: NCT05629442

This clinical trial, titled "ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer," is looking at how circulating tumor DNA (ctDNA) can help monitor rectal cancer in patients who have specif...

Not yet recruiting

Type: observational Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +1 more

SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer

NCT ID: NCT05576480

This clinical trial is exploring a new treatment approach for locally advanced rectal cancer, specifically for patients whose cancer is classified as microsatellite stable (MSS). The study will tes...

Not yet recruiting

Phase: PHASE2 Type: interventional

Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC

NCT ID: NCT05575635

This clinical trial is exploring a new treatment approach for patients with locally advanced rectal cancer, specifically those who have not received any prior cancer treatments. The researchers wan...

Not yet recruiting

Phase: PHASE2 Type: interventional

Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer

NCT ID: NCT04527861

This clinical trial is studying two different surgical techniques for patients with colorectal cancer—single-incision laparoscopic surgery (SILS) and conventional laparoscopic surgery (CLS). The go...

Recruiting

Phase: NA Type: interventional Locations: Jinan, Shandong, China, Shanghai, , China +10 more

A Study to Validate the Safety and Feasibility of ArtiSential in Colorectal Cancer Surgery Using Prospectively Constructed Multi-center Registry

NCT ID: NCT05566249

This clinical trial is looking to see how safe and effective a new surgical tool, called ArtiSential, is for performing surgeries on patients with rectal cancer and cancers of the rectosigmoid junc...

Recruiting

Type: observational Locations: Seoul, , Korea, Republic Of

Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma

NCT ID: NCT05563922

This clinical trial is studying a treatment approach for people with early low rectal cancer, which is cancer located in the lower part of the rectum. The goal is to see if a combination of chemoth...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

Early Ileostomy Closure for Rectal Cancer Patients in North America

NCT ID: NCT05027737

This clinical trial is investigating whether closing an ileostomy (a surgical opening created in the abdomen) earlier than usual is safe and beneficial for patients with rectal cancer who have unde...

Recruiting

Phase: NA Type: interventional Locations: London, Ontario, Canada, Montreal, Quebec, Canada +3 more

The OPERa Study: Evaluating QoL After Rectal Cancer Surgery

NCT ID: NCT04893876

The OPERa Study is a clinical trial aimed at understanding how rectal cancer surgery affects the quality of life (QoL) of patients in North America. Specifically, it will look at issues like bowel ...

Not yet recruiting

Type: observational

Chinese Colorectal Cancer Database

NCT ID: NCT05434026

This clinical trial, called the Chinese Colorectal Cancer Database, aims to create a comprehensive collection of information about colorectal cancer patients in China. The goal is to understand how...

Recruiting

Type: observational Locations: Beijing, , China

Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients.

NCT ID: NCT03957733

This clinical trial is looking at a new way to treat patients with rectal cancer before surgery. It involves two groups: one group will receive a combination of chemotherapy after their initial rad...

Recruiting

Phase: PHASE2 Type: interventional Locations: Mecca, Makkah Western, Saudi Arabia

Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer

NCT ID: NCT04922853

This clinical trial is studying the effects of two different lengths of chemotherapy treatment for patients with low to intermediate risk stage II/III rectal cancer. Specifically, researchers want ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chengdu, Sichuan, China, Kunming, Yunnan, China +2 more

Neoadjuvant FOLFOXIRI Versus CapeOX Chemotherapy for Local Advanced Rectal Cancer

NCT ID: NCT05201430

This clinical trial is looking at two different chemotherapy treatments for patients with locally advanced rectal cancer, which is a type of cancer in the rectum that has not spread to other parts ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Shanghai, Shanghai, China

Multicenter Study on Postoperative Urinary and Sexual Function During Laparoscopic Functional Total Mesorectum Excision

NCT ID: NCT05049317

This clinical trial is looking at how a specific type of surgery called laparoscopic functional total mesorectum excision (FTME) affects urinary and sexual functions in men with rectal cancer. Afte...

Recruiting

Phase: NA Type: interventional Locations: Wuhan, Hubei, China

Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer

NCT ID: NCT04109755

This clinical trial is exploring a new treatment approach for patients with localized rectal cancer, specifically those whose tumors are classified as microsatellite stable (MSS). The study is test...

Recruiting

Phase: PHASE2 Type: interventional Locations: Geneva, , Switzerland

Mesorectal Microbiome as a Prognostic Factor in Patients With Rectal Cancer

NCT ID: NCT04804956

This clinical trial is investigating the role of the mesorectal microbiome—tiny microorganisms living in the tissues around the rectum—in helping to predict the outcomes for patients with rectal ca...

Recruiting

Type: observational Locations: Girona, , Spain

Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer

NCT ID: NCT04287400

This clinical trial is looking at how different factors can help us understand advanced rectal cancer better. Specifically, researchers want to identify the unique characteristics of the cancer by ...

Recruiting

Type: observational Locations: Goyang Si, Gyeonggi Do, Korea, Republic Of

Robotic vs. TaTME Rectal Surgery (ROTA STUDY)

NCT ID: NCT04200027

The ROTA STUDY is a clinical trial that aims to compare two advanced surgical techniques for treating rectal cancer: robotic low anterior resection (RLAR) and transanal total mesorectal excision (T...

Not yet recruiting

Type: observational Locations: Svendborg, Southern Denmark, Denmark, Portsmouth, , United Kingdom

A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk

NCT ID: NCT04664504

This clinical trial is studying a new treatment approach for patients with rectal cancer. Specifically, it is looking at how personalized combinations of chemotherapy and radiation therapy can help...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, , China

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