Clinical Trials for Recurrent Malignant Solid Neoplasm

Find clinical trials for recurrent malignant solid neoplasm. Discover research opportunities and treatment options in your area.

17 Active Trials Found

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Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

NCT ID: NCT05286801

This clinical trial is focused on studying two medications, tiragolumab and atezolizumab, to see how well they work in treating certain types of aggressive tumors that have either returned after tr...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Durham, North Carolina, United States +41 more

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

NCT ID: NCT06126276

This clinical trial is investigating the effects of two treatments for patients with certain types of cancer known as HER2 positive solid tumors. The study compares a medication called neratinib to...

Recruiting

Phase: PHASE2 Type: interventional Locations: Durham, North Carolina, United States, Bethesda, Maryland, United States +163 more

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT ID: NCT05564377

The ComboMATCH Screening Trial is a study that aims to find effective treatments for patients with advanced solid tumors, such as certain types of breast cancer and other cancers that have spread e...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Durham, North Carolina, United States +491 more

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

NCT ID: NCT06620302

This clinical trial is exploring the effects of a new anti-cancer drug called DT2216 when added to standard chemotherapy (irinotecan) for children, teenagers, and young adults with solid tumors or ...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, New York, New York, United States +5 more

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

NCT ID: NCT04840589

This clinical trial is exploring a new treatment approach for patients with certain types of advanced solid tumors, including recurrent ovarian cancer. The study is testing a combination of two imm...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cleveland, Ohio, United States, Bethesda, Maryland, United States +5 more

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

NCT ID: NCT06320405

This clinical trial is studying a new treatment approach for patients with advanced or metastatic solid tumors, which are cancers that have spread from their original site to other parts of the bod...

Recruiting

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States

Studying TAK-243 in Patients With Advanced Cancer

NCT ID: NCT06223542

This clinical trial is studying a new medication called TAK-243 to see how safe it is and to determine the best dose for patients with advanced cancers, including types of lymphoma and solid tumors...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT ID: NCT04119024

This clinical trial is testing a new treatment for patients with advanced melanoma and other types of solid tumors that have spread in the body. The treatment involves using specially modified immu...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States, Los Angeles, California, United States +1 more

Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

NCT ID: NCT04693468

The TalaCom Trial is a research study looking at how well a new treatment called talazoparib works when combined with other drugs (palbociclib, axitinib, or crizotinib) for patients with advanced o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

NCT ID: NCT06295965

The CHANCES Study is a research trial looking at how certain changes in blood cells, known as clonal hematopoiesis, may affect women who have survived ovarian cancer. The goal is to understand if t...

Recruiting

Type: observational Locations: Seattle, Washington, United States

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

NCT ID: NCT02474160

This clinical trial is focused on collecting and storing tissue and blood samples from people diagnosed with cancer. The goal is to use these samples to help scientists better understand cancer and...

Recruiting

Type: observational Locations: New Haven, Connecticut, United States, Durham, North Carolina, United States +158 more

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

NCT ID: NCT03420963

This clinical trial is testing a new treatment for children and young adults who have solid tumors that have either come back after treatment or have not responded to previous therapies. The study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

NCT ID: NCT04870944

This clinical trial is studying a new treatment called CBL0137 for young patients with certain types of solid tumors, including cancers of the central nervous system (CNS) and lymphoma that have ei...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Philadelphia, Pennsylvania, United States +32 more

Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis

NCT ID: NCT05059678

This clinical trial is looking at a special program designed to help parents who are dealing with a serious type of cancer called metastatic or locally recurrent solid tumors. The program aims to s...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

Adoption of Audio Recording in the Outpatient Supportive Care Center

NCT ID: NCT04871477

This clinical trial is looking at how patients with advanced cancer feel about having their clinic visits recorded. The goal is to see if audio recordings can help patients remember important infor...

Not yet recruiting

Type: observational Locations: Houston, Texas, United States

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

NCT ID: NCT04851119

This clinical trial is studying a new medication called tegavivint, which is being tested to see if it can help patients with certain types of solid tumors that have either come back after treatmen...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Saint Louis, Missouri, United States +20 more

A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma

NCT ID: NCT05101356

This clinical trial is investigating a new cancer vaccine called Labvax 3(22)-23, combined with a therapy called GM-CSF, and possibly with another drug called pembrolizumab, to treat advanced stage...

Recruiting

Phase: PHASE1 Type: interventional Locations: Sacramento, California, United States

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