Clinical Trials for Renal Impairment

Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes

NCT ID: NCT07017933

This clinical trial is investigating the JuxtaFlow® Renal Assist Device (RAD), which aims to help patients with kidney problems during heart surgery. When patients with renal impairment have heart ...

A Clinical Study of MK-1084 in Participants With Renal Impairment (MK-1084-010)

NCT ID: NCT06814119

This clinical trial, titled "A Clinical Study of MK-1084 in Participants With Renal Impairment," aims to understand how the medication MK-1084 behaves in the bodies of people with kidney issues. Re...

Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls

NCT ID: NCT07012005

This clinical trial is investigating a medication called BPN14770 to understand how the body processes it, as well as its safety and how well it is tolerated in two groups of people: those with sev...

Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234

NCT ID: NCT06845813

This clinical trial is studying a medication called AZD6234 to see how it affects people with different levels of kidney problems, including those with end-stage renal disease. The researchers want...

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function

NCT ID: NCT06911320

This clinical trial is studying a new combination medication called Bemnifosbuvir/Ruzasvir to see how well it is processed in the body of people with severe liver (hepatic) or kidney (renal) impair...

Pharmacokinetics and Safety of Rupatadine in Participants With Renal Impairment Compared to Control Participants

NCT ID: NCT06708520

This clinical trial is investigating how the medication rupatadine is processed in the body and its safety for people with kidney issues compared to those with normal kidney function. Rupatadine is...

A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems

NCT ID: NCT06352411

This clinical trial is studying how a medication called BI 456906 is absorbed into the bloodstream of adults, both with and without kidney problems. The goal is to see if kidney issues affect how m...

AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment

NCT ID: NCT06611423

This clinical trial is studying a new treatment called AZD3427 to see how it affects blood flow to the kidneys in patients with heart failure and some level of kidney impairment. Heart failure with...

An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function

NCT ID: NCT06962774

This clinical trial is studying a new medication called ESK-001 to understand how it is processed in the body, specifically in people with different levels of kidney health. It includes healthy vol...

Ultra-low Dose Contrast for Endovascular Procedures

NCT ID: NCT06835127

This clinical trial is exploring the use of a very small amount of a special dye called iodinated contrast agent during a procedure aimed at improving blood flow in patients with severe leg circula...

A Study to Evaluate BMS-986278 in Participants With Normal Renal Function, Severe Renal Impairment, or End-Stage Renal Disease on Intermittent Hemodialysis

NCT ID: NCT06723535

This clinical trial is studying a new medication called BMS-986278 to understand how it affects people with different levels of kidney function. Specifically, the researchers want to see how the me...

Effect of Renal Impairment on Enpatoran Pharmacokinetics

NCT ID: NCT06589713

This clinical trial is studying how kidney problems (renal impairment) affect how the body processes a medication called enpatoran. The researchers want to understand if and how the effectiveness a...

Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes

NCT ID: NCT00948116

This clinical trial is focused on developing a special test, called a biomarker panel, to help predict kidney problems earlier in patients with diabetes. People with diabetes are at a higher risk o...

Assessment of the Pharmacokinetics and Safety of ANT3310 Combined With Meropenem in Renally Impaired Subjects

NCT ID: NCT06527677

This clinical trial is studying how well a combination of two drugs, ANT3310 and meropenem, works in people with kidney problems, including those with severe kidney disease. The researchers want to...

Safety and Pharmacokinetics Study of MBX 2109 in Adult Subjects With Normal and Impaired Renal Function

NCT ID: NCT06496217

This clinical trial is studying the safety and how the body processes a new medication called MBX 2109 in adults with different levels of kidney function, including those with normal kidney functio...

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function

NCT ID: NCT06397872

Bowel Cleansing With Renal Impairment

NCT ID: NCT05349851

This clinical trial is studying how safe and effective bowel cleansing is for patients with advanced kidney problems before a colonoscopy, which is a test that looks inside the colon. Bowel prepara...

Incidence of HANA Conditions in HIV-infected Individuals

NCT ID: NCT03483584

This clinical trial is looking at how different treatments for HIV might affect the development of certain health conditions in people living with the virus. Specifically, it aims to understand the...

A Study to Evaluate the Pharmacokinetics of HSK21542 in Subjects With Renal Impairment

NCT ID: NCT05947097

This clinical trial is studying a medication called HSK21542 to understand how it behaves in the body, especially in people with different levels of kidney impairment. The researchers want to see h...

A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor

NCT ID: NCT05298683

This clinical trial is testing a new combination of treatments for patients with multiple myeloma, a type of blood cancer. The study will look at how well isatuximab, pomalidomide, and low-dose dex...