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Clinical Trials for Rhabdomyosarcoma

Find clinical trials for rhabdomyosarcoma. Discover research opportunities and treatment options in your area.

33 Active Trials Found

Showing 33 trials on this page

Page 1 of 2

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

NCT ID: NCT06865664

This clinical trial is studying a new treatment for children and young adults with rhabdomyosarcoma (RMS), a type of cancer that affects soft tissues and is most common in kids. The researchers are...

Not yet recruiting
Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

NCT ID: NCT04796012

The VITAS trial is a research study looking at a new treatment option for children and young adults with relapsed or hard-to-treat solid tumors, specifically rhabdomyosarcoma. This trial is testing...

Recruiting
Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Houston, Texas, United States +5 more

Evolutionary Therapy for Rhabdomyosarcoma

NCT ID: NCT04388839

This clinical trial, called "Evolutionary Therapy for Rhabdomyosarcoma," is exploring different ways to use chemotherapy for children and young adults who have just been diagnosed with a specific t...

Recruiting
Phase: PHASE2 Type: interventional Locations: Birmingham, Alabama, United States, Tampa, Florida, United States +16 more

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

NCT ID: NCT06198296

This clinical trial is studying a new treatment for adults with certain types of solid tumors that have a specific protein called GPC3 on their surface. The researchers are using a special kind of ...

Not yet recruiting
Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT ID: NCT03618381

This clinical trial is looking at a new type of treatment called EGFR806 CAR T Cell Immunotherapy for children and young adults with certain types of solid tumors that have returned or didn’t respo...

Recruiting
Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

NCT ID: NCT06023641

This clinical trial is looking at a new way to treat children with rhabdomyosarcoma, a type of cancer that affects muscle tissue. The researchers want to see if a combination of different chemother...

Recruiting
Phase: PHASE2 Type: interventional Locations: Memphis, Tennessee, United States, Palo Alto, California, United States +1 more

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

NCT ID: NCT06521567

This clinical trial is studying a combination of two medications, cobolimab and dostarlimab, to find out the safest and most effective doses for children and young adults with advanced cancer, spec...

Recruiting
Phase: PHASE1 Type: interventional Locations: Roma, Lazio, Italy, Barcelona, , Spain +35 more

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

NCT ID: NCT04715191

This clinical trial is studying a new experimental treatment called CARE T cells for children and young adults with certain types of solid tumors, including liver cancer and rhabdomyosarcoma. The t...

Recruiting
Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants

NCT ID: NCT06566092

This clinical trial is exploring a new treatment using autologous tumor-infiltrating lymphocytes (TILs) for children, teenagers, and young adults who have solid tumors like soft tissue sarcoma, mel...

Recruiting
Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Saint Petersburg, Florida, United States +1 more

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT ID: NCT04897321

The 3CAR trial is a research study looking at a new type of treatment called immunotherapy for children and young adults (up to 21 years old) with specific types of solid tumors, such as neuroblast...

Recruiting
Phase: PHASE1 Type: interventional Locations: Memphis, Tennessee, United States

Exploratory Study of Personalized mRNA Vaccine in Patients With Refractory Rhabdomyosarcoma

NCT ID: NCT06932861

This clinical trial is exploring a new type of treatment for patients with a rare cancer called rhabdomyosarcoma, specifically for those whose disease has not responded to standard therapies. The t...

Not yet recruiting
Phase: EARLY_PHASE1 Type: interventional

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

NCT ID: NCT06796543

This clinical trial is exploring a new way to treat children, adolescents, and young adults with metastatic sarcoma, a type of cancer that has spread from its original site to other parts of the bo...

Recruiting
Phase: NA Type: interventional Locations: Washington, District Of Columbia, United States, Baltimore, Maryland, United States

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

NCT ID: NCT04377932

This clinical trial is testing a new experimental treatment using specially modified immune cells called AGAR T cells to fight certain types of pediatric cancers, including liver cancer and other s...

Recruiting
Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors

NCT ID: NCT04890093

This clinical trial is exploring whether a new drug called PEN-866, when combined with two existing treatments, vincristine and temozolomide, can help adolescents and young adults who have solid tu...

Recruiting
Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Washington, District Of Columbia, United States

Familial Investigations of Childhood Cancer Predisposition

NCT ID: NCT03050268

This clinical trial, called "Familial Investigations of Childhood Cancer Predisposition," is studying how certain genetic factors may increase the risk of developing specific types of childhood can...

Recruiting
Type: observational Locations: Memphis, Tennessee, United States

Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry

NCT ID: NCT06924463

This clinical trial is studying rhabdomyosarcoma, a type of cancer that affects children and young adults. Researchers are using advanced techniques to analyze small samples of tumor tissue collect...

Recruiting
Type: observational Locations: Lille, Nord, France

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT ID: NCT06625190

This clinical trial is investigating a new treatment approach for certain solid tumors in young patients, including conditions like neuroblastoma and rhabdomyosarcoma. The treatment involves using ...

Not yet recruiting
Phase: PHASE1 Type: interventional Locations: Gainesville, Florida, United States

A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors.

NCT ID: NCT06836492

This clinical trial is studying a new treatment approach for a type of pediatric cancer called rhabdomyosarcoma, which primarily affects children and young adults. Researchers want to find out how ...

Recruiting
Phase: PHASE3 Type: interventional Locations: Guangzhou, Guangdong, China

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

NCT ID: NCT06709495

This clinical trial is studying a new drug called PEEL-224, which is being tested alongside two existing medications, Vincristine and Temozolomide. The goal is to see how well this combination work...

Recruiting
Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +3 more

Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models

NCT ID: NCT06822842

This clinical trial is focused on improving the diagnosis of certain childhood cancers, specifically five types of solid tumors: neuroblastoma, medulloblastoma, Wilms tumor, hepatoblastoma, and rha...

Not yet recruiting
Type: observational

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