Clinical Trials for Stage IV Colorectal Cancer AJCC v8

Find clinical trials for stage iv colorectal cancer ajcc v8. Discover research opportunities and treatment options in your area.

21 Active Trials Found

Showing 21 trials on this page

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National Cancer Institute "Cancer Moonshot Biobank"

NCT ID: NCT04314401

The "Cancer Moonshot Biobank" is a clinical trial that aims to gather blood and tissue samples from patients diagnosed with various types of cancer, including advanced stages of breast cancer, lung...

Recruiting

Type: observational Locations: Des Moines, Iowa, United States, Scarborough, Maine, United States +177 more

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

NCT ID: NCT05691491

This clinical trial is investigating the safety and effectiveness of two anti-cancer drugs, temozolomide and M1774, for patients with advanced cancers that have spread to other parts of the body. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Haven, Connecticut, United States, Saint Louis, Missouri, United States +20 more

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

NCT ID: NCT06654037

This clinical trial is investigating the safety and effectiveness of a new anti-cancer drug called abemaciclib when used alongside standard chemotherapy (5-fluorouracil) for patients with advanced ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Orange, California, United States, Bronx, New York, United States +7 more

Intravital Microscopy in Human Solid Tumors

NCT ID: NCT03823144

This clinical trial is studying how blood vessels in solid tumors—such as those found in cancers of the stomach, pancreas, liver, colon, breast, brain, and soft tissues—work in real-time during sur...

Recruiting

Phase: NA Type: interventional Locations: Jacksonville, Florida, United States

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

NCT ID: NCT06696768

This clinical trial is looking at a new anti-cancer drug called CA-4948 (also known as Emavusertib) combined with a standard chemotherapy treatment called FOLFOX (which includes the drugs fluoroura...

Recruiting

Phase: PHASE1 Type: interventional Locations: Oklahoma City, Oklahoma, United States, Gainesville, Florida, United States +1 more

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

NCT ID: NCT05673148

The ERASur Study is a clinical trial designed to find out if adding a specific type of treatment called total ablative therapy can improve outcomes for patients with a type of colorectal cancer tha...

Recruiting

Phase: PHASE3 Type: interventional Locations: Milwaukee, Wisconsin, United States, Washington, District Of Columbia, United States +175 more

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT ID: NCT04704661

The DASH Trial is a clinical study exploring the safety and effectiveness of two anti-cancer drugs, DS-8201a and AZD6738, for patients with various types of advanced solid tumors that express the H...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Saint Louis, Missouri, United States +22 more

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

NCT ID: NCT06102902

This clinical trial is studying a new treatment approach for patients with advanced colorectal cancer that has not responded to previous therapies. The trial combines a new drug called ZEN003694 wi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Oklahoma City, Oklahoma, United States, Charlottesville, Virginia, United States +11 more

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

NCT ID: NCT05803382

This clinical trial is studying a new anti-cancer drug called ZEN003694, which is being tested alongside the usual chemotherapy drug capecitabine. The goal is to see if this combination can safely ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Oklahoma City, Oklahoma, United States +22 more

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

NCT ID: NCT06626256

This clinical trial is studying a new treatment called STIL101 for injection, designed to help patients with certain types of advanced cancers, including pancreatic, colorectal, renal cell, cervica...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

NCT ID: NCT06265285

This clinical trial is exploring whether giving a cancer treatment called nivolumab at home is just as safe and effective as receiving it in a clinic. By allowing patients to receive treatment in t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jacksonville, Florida, United States

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

NCT ID: NCT04693377

The CROME Trial is studying a new treatment approach for patients suffering from painful bone metastases, which occur when cancer spreads to the bones. The trial compares two methods: one combines ...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

An Observational Research Study to Uncover Subtypes of Cancer Cachexia

NCT ID: NCT06073431

The LOTUS-CC Study is examining a serious condition called cancer cachexia, which is the loss of weight and muscle that can occur in patients with certain types of cancer, specifically colorectal, ...

Recruiting

Type: observational Locations: Kalamazoo, Michigan, United States, Edina, Minnesota, United States +198 more

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

NCT ID: NCT05967533

This clinical trial is studying the effects of a nutritional supplement called fermented wheat germ on the immune system of patients with advanced solid tumor cancers, such as lung cancer, melanoma...

Recruiting

Phase: PHASE1 Type: interventional Locations: Sacramento, California, United States

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

NCT ID: NCT04430725

The ALLUME Study is a clinical trial that aims to find out which treatment works better for patients with certain types of cancer that have spread to other areas of the body, specifically lung canc...

Recruiting

Type: observational Locations: Houston, Texas, United States

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

NCT ID: NCT04771520

This clinical trial is studying a medication called avapritinib to see how well it works for treating certain types of advanced or spreading solid tumors that have specific genetic changes called C...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

NCT ID: NCT04221893

This clinical trial is exploring how effective radiation therapy is for treating advanced gastrointestinal cancers that have spread to other parts of the body. The goal is to see if combining radia...

Recruiting

Phase: NA Type: interventional Locations: San Francisco, California, United States

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

NCT ID: NCT05863195

The PUMP Trial is looking at a new way to treat patients with advanced colorectal cancer that has spread to the liver and cannot be surgically removed. This study is comparing two approaches: one g...

Recruiting

Phase: PHASE3 Type: interventional Locations: Durham, North Carolina, United States, Cleveland, Ohio, United States +38 more

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

NCT ID: NCT04511039

This clinical trial is studying the combination of two cancer treatments, trifluridine/tipiracil and talazoparib, to see how well they work together for patients with advanced colorectal or gastroe...

Recruiting

Phase: PHASE1 Type: interventional Locations: Buffalo, New York, United States

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

NCT ID: NCT04329494

This clinical trial is looking at a new way to give chemotherapy to patients with advanced cancers, such as ovarian, uterine, stomach (gastric), appendiceal, or colorectal cancer that has spread to...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States, Jacksonville, Florida, United States +1 more

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