Clinical Trials for Systemic Sclerosis (SSc)

Find clinical trials for systemic sclerosis (ssc). Discover research opportunities and treatment options in your area.

41 Active Trials Found

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Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

NCT ID: NCT06843239

The TibuSURE trial is a clinical study looking at a new treatment called tibulizumab for people with systemic sclerosis (also known as scleroderma). This condition causes hardening and tightening o...

Recruiting

Phase: PHASE2 Type: interventional Locations: Iowa City, Iowa, United States, London, United Kingdom +17 more

Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy

NCT ID: NCT07150000

This clinical trial is studying a new way to help doctors choose the best medicine for people with autoimmune rheumatic diseases, such as rheumatoid arthritis, lupus, and gout arthritis. These cond...

Recruiting

Type: observational

Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases

NCT ID: NCT06828042

This clinical trial is looking at a new treatment option for patients with certain autoimmune diseases, like systemic lupus erythematosus and systemic sclerosis, that have not responded well to sta...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, China

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

NCT ID: NCT06991114

This clinical trial is studying a new treatment called AlloNK, which uses natural killer (NK) cells derived from umbilical cord blood, combined with a medication called rituximab. The trial is aime...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tucson, Arizona, United States, Aventura, Florida, United States +13 more

A Phase 1 Study of ADI-001 in Autoimmune Disease

NCT ID: NCT06375993

This clinical trial is testing a new treatment called ADI-001 for patients with lupus nephritis, a kidney problem that can occur in people with lupus, an autoimmune disease. The goal of this study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Buffalo, New York, United States, Manhasset, New York, United States +1 more

A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases

NCT ID: NCT07104721

This clinical trial is testing a new treatment called YTS109 cells for adults who have certain autoimmune diseases that have not improved with standard treatments. These diseases include conditions...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Hefei, Anhui, China

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

NCT ID: NCT06308978

This clinical trial is studying a new treatment called FT819 for adults with moderate to severe active systemic lupus erythematosus (SLE), a condition where the immune system mistakenly attacks hea...

Recruiting

Phase: PHASE1 Type: interventional Locations: Minneapolis, Minnesota, United States, Omaha, Nebraska, United States +4 more

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

NCT ID: NCT07085676

This clinical trial is testing a new treatment called HBI0101 CAR-T therapy for people with certain autoimmune diseases that affect the body's B cells, such as lupus (SLE), systemic sclerosis, infl...

Recruiting

Phase: PHASE1 Type: interventional Locations: Jerusalem, Israel

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

NCT ID: NCT07087912

This clinical trial is studying a dengue vaccine called the Butantan-Dengue vaccine to see if it is safe and can help the body build protection in people who have autoimmune rheumatic diseases—cond...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: São Paulo, Sp, Brazil, São Paulo, Sp, Brazil

DERMATOMICS: Identifying Regulators of Skin Homeostasis

NCT ID: NCT06894654

The DERMATOMICS clinical trial is studying systemic sclerosis (SSc), a rare autoimmune condition that affects the skin and can cause serious complications in other organs. The goal of this research...

Recruiting

Type: observational Locations: London, United Kingdom, Leeds, United Kingdom

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

NCT ID: NCT06655155

This clinical trial is studying a new medication called efgartigimod PH20 SC to see if it can help adults with systemic sclerosis (SSc), a condition that affects the skin and other parts of the bod...

Recruiting

Phase: PHASE2 Type: interventional Locations: Belgrade, Serbia, Ann Arbor, Michigan, United States +17 more

A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

NCT ID: NCT06249438

This clinical trial is studying a new treatment called C-CAR168 for adults with certain autoimmune diseases that haven’t responded well to standard therapies. These diseases include Systemic Lupus ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

The Clinical Study on the Treatment of SSc With UTAA91 Injection.

NCT ID: NCT07000682

This clinical trial is looking at a new treatment called UTAA91 injection for people with systemic sclerosis (SSc), a serious condition that affects the skin and other organs. The main goal of the ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Wuhan, Hubei, China

A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases

NCT ID: NCT06978647

This clinical trial is looking at a new treatment called YTS109 cells for adults who have relapsed or refractory autoimmune diseases, which means their conditions have either come back or have not ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

GC012F in Patients With Autoimmune Diseases

NCT ID: NCT07072884

This clinical trial is studying a new treatment called GC012F Injection for people with certain autoimmune diseases, specifically Systemic Sclerosis and Idiopathic Inflammatory Myopathy. These are ...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional

TENS in Scleroderma

NCT ID: NCT06646913

The clinical trial titled "TENS in Scleroderma" is exploring a new way to help people with Scleroderma who also experience gastroparesis, a condition that makes it hard for the stomach to empty pro...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States

Hand Disability In Systemic Sclerosis - Digital Ulcers

NCT ID: NCT06658470

This study is checking whether the Turkish version of a hand-disability questionnaire, called the Hand Disability in Systemic Sclerosis - Digital Ulcers (HDISS-DU), works well for people with syste...

Enrolling by invitation

Type: observational Locations: Denizli, Turkey, Malatya, Turkey

PPI Refractory - GERD Mechanisms in Systemic Sclerosis

NCT ID: NCT07022912

This clinical trial is focused on understanding why some patients with systemic sclerosis (SSc) continue to experience gastroesophageal reflux disease (GERD) symptoms, like heartburn and regurgitat...

Not yet recruiting

Type: observational

Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection.

NCT ID: NCT06982534

This clinical trial is investigating a new treatment called UTAA91 injection for people suffering from systemic sclerosis (SSc), a chronic disease that causes hardening and tightening of the skin a...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Wuhan, Hubei, China

A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases

NCT ID: NCT06980597

This clinical trial, called the "Study of OL-108 in Relapsed/Refractory Autoimmune Diseases," is investigating a new treatment, OL-108, for adults suffering from specific autoimmune diseases, inclu...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, China, Beijing, China

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