Clinical Trials for Systemic Sclerosis

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

NCT ID: NCT06548607

This clinical trial is studying a new treatment called RD06-04, which is a type of targeted therapy designed to help patients with autoimmune diseases such as Systemic Lupus Erythematosus (SLE), Sy...

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

NCT ID: NCT05029336

This clinical trial is exploring a new treatment approach for children and young adults with serious autoimmune diseases, specifically systemic lupus erythematosus (SLE) and systemic sclerosis (SSc...

Rheumatology Patient Registry and Biorepository

NCT ID: NCT04402086

The Rheumatology Patient Registry and Biorepository is a clinical trial aimed at improving our understanding of various rheumatic diseases, including conditions like rheumatoid arthritis, lupus, an...

Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases

NCT ID: NCT06775912

This clinical trial is exploring a new treatment called RD06-05 for patients with certain autoimmune diseases, including systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and others. Th...

Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH

NCT ID: NCT05339087

This clinical trial is studying the effectiveness and safety of a drug called riociguat for patients who have early signs of pulmonary vascular disease, which can lead to a serious condition known ...

Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis

NCT ID: NCT04464434

This clinical trial is looking at two different treatment approaches for patients with early diffuse cutaneous systemic sclerosis (dcSSc), a serious condition that affects the skin and can impact o...

PET Imaging of Systemic Sclerosis Using FDG and 68Ga-DOTA-Siglec-9

NCT ID: NCT05108857

Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases

NCT ID: NCT06549296

This clinical trial is studying a new type of therapy called CD19CAR-T, which is designed to help patients with various autoimmune diseases, including systemic lupus erythematosus (SLE), systemic s...

Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease

NCT ID: NCT06297096

This clinical trial is studying a combination treatment of two medications, nintedanib and tocilizumab, for adults with systemic sclerosis (a condition that affects the skin and other organs) and i...

Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases

NCT ID: NCT05859997

This clinical trial is studying a new treatment called BRL-301, which is being tested for its effectiveness and safety in patients with certain autoimmune diseases, such as Systemic Lupus Erythemat...

Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk

NCT ID: NCT05098704

This clinical trial is looking at whether a medication called clopidogrel can help prevent the development of systemic sclerosis (SSc) in people who show early signs of the disease. Systemic sclero...

Personalized Home Respiratory Rehabilitation Program for Subjects with Systemic Sclerosis with Early Lung Disease

NCT ID: NCT05533034

This clinical trial is looking at a special program designed to help people with systemic sclerosis (a serious disease that can affect the lungs) who are experiencing early lung problems. The resea...

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)

NCT ID: NCT06350110

This clinical trial is investigating a new treatment using a type of engineered immune cells called CAR T cells to help patients with systemic lupus erythematosus (SLE) who have not responded to ot...

Safety and Efficacy of Itacitinib in Adults with Systemic Sclerosis

NCT ID: NCT04789850

This clinical trial is studying a medication called itacitinib to see if it is safe and effective for adults with systemic sclerosis, a condition that causes skin and internal organs to become thic...

Periodontal Health Status in Patients with Systemic Sclerosis

NCT ID: NCT05215431

This clinical trial is studying how periodontal disease, which affects the gums and teeth, impacts patients with systemic sclerosis, a condition that affects the skin and internal organs. The resea...

An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease

NCT ID: NCT06379646

This clinical trial is looking at a new treatment called YTS109 cell injection for patients with certain autoimmune diseases, such as systemic lupus erythematosus and Sjogren's syndrome, that have ...

Evaluation of Muscle Involvement in Systemic Sclerosis

NCT ID: NCT06051773

This clinical trial is studying how muscle involvement affects patients with systemic sclerosis (SSc), a condition that can cause hardening and tightening of the skin and connective tissues. Resear...

Interstitial Lung Disease Trajectories in Patients With Systemic Sclerosis

NCT ID: NCT05345795

This clinical trial is focused on understanding how interstitial lung disease (ILD) develops in patients with systemic sclerosis (SSc), a disease that affects the skin and internal organs. ILD is a...

Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease

NCT ID: NCT05482607

This clinical trial is researching how different patterns seen in high-resolution chest CT scans (HRCT) can help understand lung problems in patients with systemic sclerosis (SSc), an autoimmune di...

Relmacabtagene Autoleucel for the Treatment of Systemic Sclerosis

NCT ID: NCT06414135

This clinical trial is studying a new treatment called Relmacabtagene Autoleucel (or Relma-cel) for people with early diffuse systemic sclerosis, a serious autoimmune disease that can cause skin an...