Clinical Trials for Thalassemia

A Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participants

NCT ID: NCT07023029

This clinical trial is studying a new medicine called Etavopivat, which is being developed to help treat sickle cell disease. However, in this study, the researchers want to see how Etavopivat affe...

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

NCT ID: NCT05736419

This clinical trial is investigating a new treatment approach for individuals with Sickle Cell Disease or β-Thalassemia who are preparing to receive a stem cell transplant from a donor. The goal is...

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

NCT ID: NCT06313398

This clinical trial is studying how long red blood cells (RBCs) last in people with sickle cell disease (SCD) and other blood disorders, including those who have undergone a bone marrow transplant....

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

NCT ID: NCT05477563

This clinical trial is studying a new treatment called CTX001 for people with transfusion-dependent β-thalassemia (TDT) or severe sickle cell disease (SCD). The treatment involves modifying a patie...

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

NCT ID: NCT04398628

The ATHN Transcends study is researching how safe and effective different treatments are for people with various non-cancerous blood disorders, such as hemophilia, von Willebrand disease, and other...

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

NCT ID: NCT05356195

This clinical trial is studying a new treatment called CTX001 for children with a serious blood disorder known as transfusion-dependent beta-thalassemia (TDT). TDT is a condition where the body doe...

A Long-term Follow-up Study in Participants Who Received CTX001

NCT ID: NCT04208529

European Rare Blood Disorders Platform (ENROL)

NCT ID: NCT06250595

The ENROL trial, also known as the European Rare Blood Disorders Platform, is focused on improving the understanding and treatment of rare blood disorders, which include conditions like anemia, leu...

RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)

NCT ID: NCT06213402

The RADeep study is looking into Rare Anemia Disorders (RADs), which are a group of uncommon conditions where people experience anemia, a shortage of healthy red blood cells. These disorders, such ...

Effect of Folic Acid Supplementation in Pregnant Women Having Thalassaemia Trait

NCT ID: NCT04310059

This clinical trial is studying how folic acid supplementation affects pregnant women who have thalassaemia trait, a condition that can impact the production of red blood cells. Folic acid is impor...

Assessment of Cognitive Function and Quality of Life in Thalassemic Children at Sohag University Hospital

NCT ID: NCT06058260

This clinical trial is looking at how thalassemia affects the thinking skills and quality of life in children aged 4 to 18 years. Thalassemia is a lifelong blood disorder that requires regular trea...

Atrial Fibrillation in Beta-Thalassemia

NCT ID: NCT05508932

This clinical trial is studying the differences between patients with beta-thalassemia who have a heart condition called atrial fibrillation and those who do not have this condition. Atrial fibrill...

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

NCT ID: NCT01758042

This clinical trial aims to explore the effects of a combined bone marrow and kidney transplant for patients with chronic kidney disease and certain blood disorders, such as leukemia and lymphoma. ...