Clinical Trials for Tuberculosis

Evaluating Next Generation LAM Assays and Molecular Diagnostics (POC and Near POC) for the Diagnosis of TB Among People With Presumptive TB: a Prospective Multicentre Diagnostic Accuracy Study

NCT ID: NCT06019052

This clinical trial, called the DriveDx4TB study, is designed to test new tests for diagnosing tuberculosis (TB) in people who might have the disease. The study aims to evaluate updated diagnostic ...

Safety and Challenge Study of BCG TICE(R) Vaccination to Test Tuberculosis Immunity in Heathy Humans

NCT ID: NCT06845358

This clinical trial, called the Safety and Challenge Study of BCG TICE® Vaccination, is designed to test how safe and effective a vaccine called TICE® BCG is for helping the body build immunity aga...

Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment

NCT ID: NCT06497465

This clinical trial is studying a new treatment approach for people who have both HIV and tuberculosis (TB) and have not yet received any HIV treatment. The trial is comparing two different ways of...

Detection of Mycobacterium Tuberculosis in Blood of TB Patients and Their Contacts in Uganda

NCT ID: NCT06751706

Candidate Clinical Correlate of Prognostic Outcome for TB Study

NCT ID: NCT07018076

The Candidate Clinical Correlate of Prognostic Outcome for TB (C3PO) study is part of a larger research effort aimed at improving how we predict the risk of tuberculosis (TB) coming back after trea...

Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda

NCT ID: NCT05917210

This clinical trial, called "Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda," is designed to see how well a new program helps people with tuberculosis (TB), especial...

Training Protocol on the Natural History of Tuberculosis

NCT ID: NCT01212003

This clinical trial is focused on understanding tuberculosis (TB), an infectious disease that affects many people around the world. The researchers want to learn more about how TB develops and prog...

Testing Health Workers At Risk to Advance Our Understanding of TB Infection

NCT ID: NCT06221488

The THWART-TB clinical trial is studying tuberculosis (TB) infection among health workers in Cape Town, South Africa. Tuberculosis is a serious disease that affects the lungs and can be life-threat...

Shortened Regimen for Drug-susceptible TB in Children

NCT ID: NCT06253715

This clinical trial is studying a new, shorter treatment for drug-susceptible tuberculosis (TB) in children under 10 years old. Currently, treating TB usually takes four to six months, but research...

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

NCT ID: NCT05586230

This clinical trial is studying how well a single dose of a medication called pretomanid works when added to a standard treatment plan for children with rifampicin-resistant tuberculosis (RR-TB), w...

Systems Analysis and Improvement Approach to Prevent TB

NCT ID: NCT06314386

This clinical trial is focused on improving the care and treatment of tuberculosis (TB) in rural clinics in Eastern Cape, South Africa. Researchers are using a method called the Systems Analysis an...

Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated Volunteers

NCT ID: NCT05547464

This clinical trial is looking at the safety and immune responses of two new RNA-based vaccines designed to help protect against tuberculosis (TB) in people who have already received a BCG vaccine,...

LIFE-TB ; Long-Term Impacts on Lung Health and Life After Tuberculosis in Korea

NCT ID: NCT06946784

The LIFE-TB trial is a study looking at the long-term effects of tuberculosis (TB) on lung health and overall well-being in people living in Korea. Researchers are interested in understanding how T...

Novel Triple-dose Tuberculosis Retreatment Regimen

NCT ID: NCT04260477

This clinical trial is studying a new high-dose treatment for patients who have had recurring pulmonary tuberculosis (TB) that is still sensitive to rifampicin, a common TB medication. The goal is ...

ID93/GLA-SE Vaccination + BCG Challenge

NCT ID: NCT06670755

The clinical trial titled "ID93/GLA-SE Vaccination + BCG Challenge" is investigating a new tuberculosis (TB) vaccine called ID93/GLA-SE. This study aims to determine if the vaccine is safe for peop...

Development of the Drug and Alcohol Respiratory Health Test

NCT ID: NCT06921278

This clinical trial is focused on creating a new test called the Drug and Alcohol Respiratory Health Test (DARHT). The goal of this test is to help doctors assess how substances like tobacco, alcoh...

TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts

NCT ID: NCT06022146

The TB YOUTH trial is a study looking at a new way to treat latent tuberculosis (LTBI) in students who may have been exposed to someone with active tuberculosis (TB) in their school. The researcher...

Active Screening of Latent Tuberculosis Infection in School Contacts of Active Tuberculosis Patients

NCT ID: NCT06033807

This clinical trial is looking into how many students who are in close contact with active tuberculosis (TB) patients have a latent TB infection, which means they carry the bacteria but do not show...

Prospective Cohort of People Starting Treatment for Tuberculosis Disease in France (FrenchTB)

NCT ID: NCT06893757

The French Tuberculosis Cohort study, also known as FrenchTB, is designed to follow people who have recently been diagnosed with tuberculosis (TB) and are starting treatment. This study aims to col...

Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)

NCT ID: NCT05989802

The R2D2 Kids and ADAPT for Kids trials are studying new and better ways to diagnose tuberculosis (TB) in children under 15 years old. TB is a serious disease that can lead to many childhood deaths...