A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT ID: NCT05514054

This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considere...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT ID: NCT06383390

The TRIUMPH-OUTCOMES study is looking at a new treatment called retatrutide, which is given once a week, to see if it can help reduce serious heart problems and protect kidney function in adults wh...

Recruiting

Phase: PHASE3 Conditions: Chronic Kidney Disease (CKD), Atherosclerotic Cardiovascular Disease (ASCVD)

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT ID: NCT06926868

The IZABRIGHT-Breast01 clinical trial is studying a new treatment option called Izalontamab Brengitecan (or iza-bren) for patients with a type of breast cancer known as triple-negative breast cance...

Not yet recruiting

Phase: PHASE2 Conditions: Breast Neoplasms

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

NCT ID: NCT06074588

This clinical trial is studying a new treatment called sacituzumab tirumotecan for patients with advanced or metastatic non-small cell lung cancer (NSCLC) that has specific genetic changes, such as...

Recruiting

Phase: PHASE3 Conditions: Non-small Cell Lung Cancer (NSCLC)

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

NCT ID: NCT06132958

This clinical trial is studying a new treatment called MK-2870, also known as sacituzumab tirumotecan, for women with endometrial cancer who have already received certain types of treatments. These...

Recruiting

Phase: PHASE3 Conditions: Endometrial Cancer

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

NCT ID: NCT06136650

This clinical trial is studying a new medication called opevesostat (MK-5684) to see how well it works when combined with hormone replacement therapy (HRT) for men with metastatic castration-resist...

Recruiting

Phase: PHASE3 Conditions: Prostatic Neoplasms, Metastatic Castration-resistant Prostate Cancer (mCRPC)

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

NCT ID: NCT06459180

This clinical trial is studying a treatment called sacituzumab tirumotecan for women with recurrent or metastatic cervical cancer, which means the cancer has come back or spread after initial treat...

Recruiting

Phase: PHASE3 Conditions: Cervical Cancer

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

NCT ID: NCT06629779

This clinical trial is studying a new drug called PF-06821497 (also known as Mevrometostat) to see if it works better when combined with another medication called enzalutamide for men with metastat...

Recruiting

Phase: PHASE3 Conditions: Metastatic Castration-Resistant Prostate Cancer

A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL

NCT ID: NCT05748171

This clinical trial is studying a medication called Inotuzumab Ozogamicin (InO) to see how well it works for children and teenagers aged 1 to under 18 who have a type of leukemia called acute lymph...

Recruiting

Phase: PHASE2 Conditions: ACUTE LYMPHOBLASTIC LEUKEMIA

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT ID: NCT06760637

This clinical trial is studying a new treatment called PF-07220060, given alongside letrozole, for adults with a specific type of breast cancer known as HR-positive HER2-negative breast cancer. Thi...

Recruiting

Phase: PHASE3 Conditions: Breast Cancer

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

NCT ID: NCT06356129

This clinical trial is studying a new treatment for patients with a type of cancer called high-risk large B-cell lymphoma (LBCL). Researchers want to see if adding a medication called golcadomide t...

Recruiting

Phase: PHASE3 Conditions: Large B-cell Lymphoma

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

NCT ID: NCT06618287

This clinical trial is studying a new treatment called BMS-986507, which is being tested in combination with other drugs for adults who have advanced solid tumors, like lung cancer. The main goals ...

Recruiting

Phase: PHASE1 Conditions: Lung Cancer

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT ID: NCT06395103

This clinical trial, called Substudy 01A, is investigating a new treatment called zilovertamab vedotin for children and young adults with certain types of blood cancers and solid tumors. Specifical...

Recruiting

Phase: PHASE1 Conditions: Neuroblastoma, Diffuse Large B-cell Lymphoma +3 more

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

NCT ID: NCT06353386

This clinical trial, named Substudy 01A, is exploring whether a new treatment called opevesostat, either on its own or combined with other therapies, is safe and effective for men with metastatic c...

Recruiting

Phase: PHASE1 Conditions: Prostatic Neoplasms, Castration-Resistant

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

NCT ID: NCT06356311

This clinical trial is studying a new treatment called sacituzumab tirumotecan (MK-2870) for patients with advanced or metastatic gastroesophageal adenocarcinoma, which is a type of cancer affectin...

Recruiting

Phase: PHASE3 Conditions: Gastroesophageal Cancer

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

NCT ID: NCT05614739

This clinical trial is studying a new treatment called LOXO-435 for patients with certain types of cancer, particularly those affecting the urinary system, like bladder and ureteral cancers. The tr...

Recruiting

Phase: PHASE1 Conditions: Neoplasm Metastasis, Urinary Bladder Neoplasms +1 more

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

NCT ID: NCT05999994

This clinical trial is focused on testing new cancer drugs specifically designed for children and young adults. It is part of a larger research effort that allows multiple studies to be conducted u...

Recruiting

Phase: PHASE2 Conditions: Neoplasms, Child +1 more

Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients

NCT ID: NCT06447480

This clinical trial is studying how effective an oral medication called isotretinoin is in treating moderate acne in patients with darker skin types (Fitzpatrick skin types IV, V, and VI) compared ...

Recruiting

Phase: PHASE3 Conditions: Acne Vulgaris

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

NCT ID: NCT04956640

This clinical trial is studying a new drug called LY3537982 to see if it is safe and effective for cancer patients who have a specific genetic mutation known as KRAS G12C. The trial is focused on p...

Recruiting

Phase: PHASE1 Conditions: Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms +4 more

Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine Department

NCT ID: NCT04104529

This clinical trial is focused on creating a special database that collects important clinical and biological information from patients being treated with metabolic radiotherapy for certain types o...

Recruiting

Phase: NA Conditions: Prostate Cancer, Neuroendocrine Tumors +1 more

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Clinical Trials in Bordeaux, Aquitaine

24 Active Trials Found in Bordeaux

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine Department