A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

NCT ID: NCT02339571

This clinical trial is investigating the effectiveness and side effects of two immunotherapy drugs, nivolumab and ipilimumab, either alone or combined with another drug called sargramostim, for pat...

Recruiting

Phase: PHASE2 Conditions: Stage IV Cutaneous Melanoma AJCC v6 and v7, Stage III Cutaneous Melanoma AJCC v7

Belimumab With Rituximab for Primary Membranous Nephropathy

NCT ID: NCT03949855

This clinical trial is exploring a new treatment option for adults with primary membranous nephropathy, a condition that can lead to nephrotic syndrome, where the kidneys leak too much protein into...

Recruiting

Phase: PHASE2 Conditions: Nephrotic Syndrome, Membranous Nephropathy

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

NCT ID: NCT04166409

This clinical trial is studying two different treatments for patients with low-grade glioma, a type of brain tumor. The trial compares a new drug called selumetinib, which may help kill tumor cells...

Recruiting

Phase: PHASE3 Conditions: Low Grade Glioma, Low Grade Astrocytoma +2 more

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

NCT ID: NCT04576117

This clinical trial is looking at how well a drug called selumetinib works alone compared to when it is combined with another drug called vinblastine in treating young patients with low-grade gliom...

Recruiting

Phase: PHASE3 Conditions: Recurrent WHO Grade 2 Glioma, Recurrent Low Grade Astrocytoma +3 more

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

NCT ID: NCT04634552

This clinical trial is studying a new treatment called talquetamab for people with relapsed or refractory multiple myeloma, which is a type of blood cancer. The goal is to see how well this treatme...

Recruiting

Phase: PHASE2 Conditions: Hematological Malignancies

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

NCT ID: NCT05256225

This clinical trial is studying the effects of adding two targeted therapies, trastuzumab (also known as Herceptin) and pertuzumab, to standard chemotherapy for women with certain types of uterine ...

Recruiting

Phase: PHASE3 Conditions: Endometrial Carcinoma, Endometrial Serous Adenocarcinoma +6 more

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

NCT ID: NCT05554406

This clinical trial, called the MyeloMATCH Treatment Trial, is investigating different treatment options for adults who have recently been diagnosed with a serious form of blood cancer called high-...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm +2 more

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT ID: NCT05675410

This clinical trial is studying whether adding two specific drugs, brentuximab vedotin and nivolumab, to the standard treatment for early-stage Hodgkin lymphoma can help patients live longer and ex...

Recruiting

Phase: PHASE3 Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

NCT ID: NCT05754957

This clinical trial is studying a medication called milvexian to see if it can help reduce the risk of serious heart problems in patients who have recently experienced an acute coronary syndrome (A...

Recruiting

Phase: PHASE3 Conditions: Acute Coronary Syndrome

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

NCT ID: NCT05923073

This clinical trial is studying a medication called guselkumab to see how well it works for children and teenagers with moderately to severely active Crohn's Disease, a condition that causes inflam...

Recruiting

Phase: PHASE3 Conditions: Crohn's Disease

A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

NCT ID: NCT06080789

This clinical trial is studying a new treatment called RABI-767 for patients with acute pancreatitis, a serious condition that affects the pancreas. The main goal is to see if a single dose of RABI...

Recruiting

Phase: PHASE2 Conditions: Acute Pancreatitis

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

NCT ID: NCT06124157

This clinical trial is studying a new treatment approach for children, adolescents, and young adults with a type of leukemia called Philadelphia chromosome positive (Ph+) or Philadelphia chromosome...

Recruiting

Phase: PHASE3 Conditions: B Acute Lymphoblastic Leukemia

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

NCT ID: NCT06312137

This clinical trial is investigating whether a combination of two treatments, pembrolizumab and sacituzumab tirumotecan, can help patients with a type of lung cancer called non-small cell lung canc...

Recruiting

Phase: PHASE3 Conditions: Non Small Cell Lung Cancer

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

NCT ID: NCT06317662

This clinical trial is studying whether adding two specific anti-cancer treatments, called venetoclax and blinatumomab, to the usual chemotherapy can help infants with a type of leukemia known as a...

Recruiting

Phase: PHASE2 Conditions: B Acute Lymphoblastic Leukemia, Acute Leukemia of Ambiguous Lineage

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

NCT ID: NCT06319820

This clinical trial is studying a new treatment called TAR-210 for patients with non-muscle invasive bladder cancer, which means the cancer is present in the bladder but hasn't spread to deeper tis...

Recruiting

Phase: PHASE3 Conditions: Non-Muscle Invasive Bladder Cancer

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NCT ID: NCT06422143

This clinical trial is exploring a new treatment approach for patients with metastatic squamous non-small cell lung cancer (NSCLC). The study is testing whether adding a drug called sacituzumab tir...

Recruiting

Phase: PHASE3 Conditions: Non-small Cell Lung Cancer, NSCLC

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

NCT ID: NCT06450639

This clinical trial is studying a medication called satralizumab to see how well it works and if it is safe for boys with Duchenne muscular dystrophy (DMD), a condition that affects muscle strength...

Recruiting

Phase: PHASE2 Conditions: Duchenne Muscular Dystrophy

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

NCT ID: NCT06589804

This clinical trial is studying whether adding a medication called cetuximab to the standard treatment pembrolizumab can better help patients with certain types of head and neck cancers that have r...

Recruiting

Phase: PHASE3 Conditions: Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma +19 more

A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder

NCT ID: NCT06817356

This clinical trial is studying a new treatment called mazdutide for people who have Alcohol Use Disorder (AUD), which means they have a strong dependence on alcohol. The goal of the study is to se...

Recruiting

Phase: PHASE2 Conditions: Alcohol Use Disorder

Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

NCT ID: NCT07003919

This clinical trial, called the COMFORT Toddlers study, is looking at the safety of a peanut allergy treatment called the Viaskin® Peanut Patch in young children aged 1 to 3 years old. Specifically...

Recruiting

Phase: PHASE3 Conditions: Allergy, Peanut Allergy

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Clinical Trials in Little Rock, Arkansas

514 Active Trials Found in Little Rock

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Belimumab With Rituximab for Primary Membranous Nephropathy

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder

Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)