Clinical Trials for Bipolar I Disorder

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

NCT ID: NCT04777357

This clinical trial is studying a medication called cariprazine to see how well it works for treating depressive episodes in children and teenagers aged 10 to 17 who have bipolar I disorder. Bipola...

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

NCT ID: NCT05064319

This clinical trial is studying the effects of a medication called Gabapentin in people who have Bipolar Disorder and also use marijuana. The goal is to see if Gabapentin can help balance certain c...

A Study of Spoken Language in Mania

NCT ID: NCT05956340

This clinical trial is exploring how voice and speech may change during episodes of mania in people with Bipolar I Disorder. Researchers want to understand these changes better to improve treatment...

Sequential Multiple Assignment Randomized Trial for Bipolar Depression

NCT ID: NCT06433635

This clinical trial is looking to find out how effective four different treatments are for adults with Bipolar I Disorder who are currently experiencing a depressive episode. The study will compare...

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

NCT ID: NCT05837104

This clinical trial is studying the effectiveness and safety of a combination of magnesium and vitamin B6 in helping people with their first episode of bipolar I disorder. The goal is to see if thi...

Observational Study of Oral Cariprazine Capsules to Assess Change in Disease Activity in Adult Participants With Bipolar I Disorder

NCT ID: NCT06256367

This clinical trial is studying the effects of a medication called cariprazine (brand name Vraylar) in adults who have been diagnosed with Bipolar I disorder (BP-I) and are currently experiencing a...

Open Label Extension Study of NCT06221852

NCT ID: NCT06558201

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder

NCT ID: NCT05303064

This clinical trial is studying how a new treatment, OLZ/SAM, affects weight gain in young people with schizophrenia or bipolar I disorder compared to a standard medication called olanzapine. The r...

Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

NCT ID: NCT04987229

Children's Bipolar Network Treatment Trial I

NCT ID: NCT05427123

The Children's Bipolar Network Treatment Trial I is a study designed to better understand and treat children and teenagers aged 9 to 19 who have bipolar disorder and related conditions. The trial a...

SYNCED - SYNChronized Eating in Bipolar Depression Study

NCT ID: NCT06560957

The SYNCED study is exploring how a specific eating pattern called time-restricted eating (TRE) might help people with bipolar depression. This involves eating all meals within a set window of time...

Safety and Tolerability of Open-Labeled Iloperidone in Adolescents

NCT ID: NCT05648591

This clinical trial is studying a medication called iloperidone to see how safe it is and how well it can be tolerated by adolescents aged 12 to 17 who have schizophrenia or bipolar I disorder. The...

Study of Oral ABBV-932 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Bipolar I or II Disorder

NCT ID: NCT06605599

This clinical trial is studying a new medication called ABBV-932 to see how safe and effective it is for adults with Bipolar I or II Disorder, particularly during depressive episodes. Bipolar disor...

NMDA Receptor Modulation for the Treatment of Bipolar I Disorder

NCT ID: NCT05977023

This clinical trial is studying a new treatment for Bipolar I Disorder (BD-I), particularly focusing on the depressive episodes that many patients experience. Researchers are looking at a special m...

LHC-CIDI-5 in Hong Kong

NCT ID: NCT06804525

This clinical trial is looking at a new tool called the life history calendar (LHC) to help improve the way we assess mental health disorders in Hong Kong. The LHC is designed to assist people in r...

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

NCT ID: NCT06696755

This clinical trial is studying a new medication called Icalcaprant, aimed at helping adults with Bipolar I or II disorder, particularly during depressive episodes. The trial will involve about 237...

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

NCT ID: NCT06221852

This clinical trial is exploring the potential benefits of a ketogenic diet, which is a high-fat, low-carbohydrate eating plan, combined with standard treatments for individuals experiencing their ...

Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions

NCT ID: NCT06494397

This clinical trial is designed to study two medications, VHX-896 and iloperidone, in patients with schizophrenia or bipolar I disorder. The main goal is to understand how these drugs work in the b...

Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression

NCT ID: NCT05339074

This clinical trial is studying the use of ketamine infusions to help people with treatment-resistant bipolar depression, which means that their depression hasn't improved with standard treatments....

Ketamine for Treatment-Resistant Bipolar Disorder

NCT ID: NCT05004896

This clinical trial is studying the use of ketamine, a medication that has shown promise in quickly alleviating depression, for people with bipolar disorder who have not responded well to other tre...