Clinical Trials for Brain Diseases

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

NCT ID: NCT05508789

The TRAILBLAZER-ALZ 5 trial is studying a medication called donanemab to see if it can help people with early symptoms of Alzheimer’s disease. The goal is to find out how safe the medication is and...

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT ID: NCT05386108

This clinical trial is investigating a combination of two medications, abemaciclib and elacestrant, to see how well they work for patients with brain metastases from estrogen receptor-positive (ER+...

Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands

NCT ID: NCT06193252

The Slow-SPEED-NL trial is studying whether a smartphone app can help people with a condition called isolated REM sleep behavior disorder (iRBD) increase their physical activity levels over 24 mont...

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

NCT ID: NCT06993142

The Slow-SPEED trial is studying whether a smartphone app can help people with specific genetic mutations (LRRK2 G2019S or GBA1 N370S) increase their daily physical activity over two years. The goa...

A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke

NCT ID: NCT06712004

This clinical trial, called BCAIS-I, is looking to understand how effective two different doses of a medication called bevifibatide are for improving recovery after an acute ischemic stroke, which ...

Exploratory Study Using a New Head-only PET Scanner / ExploreNeuroLF

NCT ID: NCT06344871

This clinical trial, called ExploreNeuroLF, is studying a new type of brain imaging called the NeuroLF prototype, which is a special head-only PET scanner. This scanner aims to capture images of th...

Emergency Stroke Unit for Acute Cerebrovascular Events: A Prospective, Single-arm Trial With a Historical Control Group

NCT ID: NCT06728592

This clinical trial is studying a new approach to treating acute ischemic strokes in patients. The trial is testing an Emergency Stroke Unit (ESU) located in the Accident and Emergency Department. ...

Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial

NCT ID: NCT06249776

The Gravity Stent-Retriever System trial is studying a new device called the Supernova, which is designed to help treat strokes caused by blood clots blocking blood flow to the brain. This trial ai...

VIrtual Reality Glasses Use to Improve Lateropulsion and the Post-stroke Postural Vertical

NCT ID: NCT04911738

The VIRGIL clinical trial is exploring how using virtual reality glasses in a tilted room can help improve balance and body orientation in people who have had a stroke. The study aims to see if thi...

Endovascular Treatment Beyond 24 Hours for Acute Ischemic Stroke Caused by Anterior Circulation Large Vessel Stenosis

NCT ID: NCT06959199

The EVT-BELATED trial is a clinical study looking at whether a specific procedure called endovascular therapy (EVT) can help patients who have had a stroke caused by a blocked blood vessel in the b...

Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation

NCT ID: NCT06954610

The CARE-AF trial is studying how certain clinical factors and heart-related tests can help predict the risk of stroke in patients with atrial fibrillation (AF), a common heart condition. Atrial fi...

Effect of Large Neutral Amino Acids in Adults With Classical Phenylketonuria

NCT ID: NCT06337864

This clinical trial is exploring a new treatment option for adults with Classical Phenylketonuria (PKU), a condition that affects how the body processes certain proteins. The study is looking at th...

Biobank and Brain Health in Bordeaux.

NCT ID: NCT05322343

The "Biobank and Brain Health in Bordeaux" study is researching how our brains age and what factors influence this process. Specifically, the trial aims to understand how things like nutrition and ...

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT ID: NCT03911388

This clinical trial is studying a new treatment called G207, which is an experimental virus therapy designed to target certain types of brain tumors in children and young adults. Specifically, it f...

Evaluation of the Feasibility of Camera Measurement of Colorimetric Parameters of the Brain During Neurosurgery Operations: Tissue Oximetry and Endogenous or Induced Fluorescence

NCT ID: NCT06651463

This clinical trial is looking at a new way to help neurosurgeons identify healthy and unhealthy areas of the brain during surgery. The study aims to see if using a special camera can measure the c...

University of Central Florida CereBank

NCT ID: NCT06876857

The University of Central Florida is starting a clinical trial called the CereBank to help researchers study brain diseases and injuries. This project aims to collect samples, like blood and tissue...

Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance

NCT ID: NCT06871969

This clinical trial is studying a new device called StrokePointer, which is designed to help ambulance personnel quickly identify patients who might be having a specific type of stroke called large...

Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients

NCT ID: NCT06809959

This clinical trial is studying a new approach to help improve hand and arm function in stroke patients. Many people who have had a stroke struggle with using their hands, and this study focuses on...

Safety and Efficacy of Remote Ischemic Preconditioning in Patients with Aneurysmal Subarachnoid Hemorrhage After Aneurysm Clipping

NCT ID: NCT06819657

This clinical trial is studying a treatment called Remote Ischemic Conditioning (RIC) for patients who have had a serious brain condition known as aneurysmal subarachnoid hemorrhage (aSAH). This co...

Brain Tissue Specimen Collection

NCT ID: NCT00593203