Clinical Trials for Cardiomyopathies

ElectroPhySiological Characterization Of the Arrhythmia Substrate for Sudden Cardiac Death PrEdiction

NCT ID: NCT07020702

The EP-SCOPE trial is a study that is looking at how to better predict the risk of life-threatening heart rhythm problems, known as ventricular arrhythmias, in patients with certain types of heart ...

Flecainide in Idiopathic Premature Ventricular Contractions and Related Cardiomyopathy

NCT ID: NCT06949748

The UNIFLECA study is investigating the use of a medication called flecainide in adults who experience frequent premature ventricular contractions (PVCs) that are not caused by any known heart prob...

Pediatric Cardiomyopathy Mutation Analysis

NCT ID: NCT02432092

This clinical trial, called the Pediatric Cardiomyopathy Mutation Analysis, is focused on understanding the genetic causes of cardiomyopathy, a condition that affects the heart muscle and can lead ...

PKP2-ACM Natural History Study

NCT ID: NCT06644742

The PKP2-ACM Natural History Study is designed to learn more about a specific type of heart condition called Arrhythmogenic Cardiomyopathy (ACM), particularly in patients with a genetic change know...

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

NCT ID: NCT06563895

The ACT-EARLY Study is a clinical trial investigating a new experimental drug called acoramidis, aimed at preventing or delaying the onset of a serious condition known as transthyretin amyloidosis ...

AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)

NCT ID: NCT05890716

The WILLEM clinical trial is studying a new technology called Willem™, which uses artificial intelligence (AI) to analyze heart activity through electrocardiograms (ECGs). This study aims to see if...

Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia

NCT ID: NCT05302271

This clinical trial is looking at a new gene therapy called AAVrh.10hFXN to see if it can help treat heart problems caused by Friedreich's ataxia (FA), a genetic condition that affects movement and...

Validation of the Prognostic Impact of a Retinal Photograph-based Cardiovascular Disease Risk Stratification System in de Novo HFrEF

NCT ID: NCT06978998

This clinical trial is studying a new way to predict the risk of heart problems in people with a specific type of heart failure called heart failure with reduced ejection fraction (HFrEF). Research...

The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

NCT ID: NCT05034432

The PIVATAL Study is a clinical trial designed to study how a procedure called ventricular arrhythmia (VTA) ablation can help patients with heart problems who are getting a Left Ventricular Assist ...

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

NCT ID: NCT06080074

This clinical trial is studying the safety and effectiveness of a device called the Cardiohelp System, which is used for a treatment called VA-ECMO in children who have severe heart failure. The ma...

Healthcare Utilization and Economic Burden of Cardiomyopathy in China

NCT ID: NCT06893731

Mayo AVC Registry and Biobank

NCT ID: NCT03049254

The Mayo AVC Registry and Biobank is a research study aimed at understanding a heart condition called Arrhythmogenic Ventricular Cardiomyopathy (AVC), which can cause serious issues like heart fail...

Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy

NCT ID: NCT06846086

This clinical trial is studying the effects of melatonin, a natural hormone, on patients who have cardiomyopathy, a condition that affects the heart muscle and can lead to heart problems. The goal ...

Cardiovascular Multimodality Imaging Study

NCT ID: NCT06610019

The Cardiovascular Multimodality Imaging Study is designed to better understand heart diseases, particularly focusing on conditions like cardiomyopathy, which affects the heart muscle. This study i...

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

NCT ID: NCT05377320

The PACT trial is a study designed to see if a new tool can help cancer survivors and their heart doctors make better decisions about heart health. This tool, which can be accessed through electron...

Cardiac Blood Flow Patterns Associated With Left Ventricular Myocardial Damage

NCT ID: NCT03253835

Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation

NCT ID: NCT06813443

This clinical trial is looking to better understand cardiomyopathy, a condition that affects the heart muscle and can lead to heart failure or the need for a heart transplant. Researchers want to f...

Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion

NCT ID: NCT04166331

The ADAPT trial is studying whether a medication called Dobutamine can help improve blood flow and reduce organ problems in patients who have septic shock and septic cardiomyopathy. Septic shock is...

Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention

NCT ID: NCT00733590

**Clinical Trial Summary: Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention** This clinical trial is studying how certain heart problems can help identify patients at h...

AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA

NCT ID: NCT06748261

This clinical trial is studying how artificial intelligence (AI) can help doctors better screen and diagnose heart conditions called cardiomyopathies using a special imaging test known as coronary ...