Clinical Trials for Cardiovascular Disease

Find clinical trials for cardiovascular disease. Discover research opportunities and treatment options in your area.

52 Active Trials Found

Showing 52 trials on this page

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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers

NCT ID: NCT04216342

This clinical trial is studying a new drug called Fx-5A, which researchers believe might help treat heart disease and related inflammation. The main goal is to find out if Fx-5A is safe to use and ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

NCT ID: NCT03372733

This clinical trial is studying the effects of a special oil rich in Omega-7 fatty acids, specifically palmitoleic acid, on heart health and feelings of fullness in healthy adults. Researchers beli...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Impact of Elastin Mediated Vascular Stiffness on End Organs

NCT ID: NCT02840448

This clinical trial is studying how the stiffness of blood vessels in people with Williams Syndrome (WS) and supravalvular aortic stenosis (SVAS) affects different organs in the body, such as the h...

Recruiting

Type: observational Locations: Charleston, South Carolina, United States, Bethesda, Maryland, United States +3 more

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT ID: NCT07000123

This clinical trial is studying a new medication called AZD0780, which is designed to lower levels of LDL cholesterol (often referred to as "bad" cholesterol) in the blood. The trial is for adults ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Barcelona, Spain, Rochester, Minnesota, United States +402 more

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

NCT ID: NCT01316783

This is an observational genetics study called Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations. Researchers are studying how genes and other health information rela...

Enrolling by invitation

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Natural History Study of CADASIL

NCT ID: NCT05072483

This clinical trial is studying a genetic condition called CADASIL, which affects blood vessels in the brain and can lead to serious problems like strokes and dementia. The goal is to understand ho...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Columbus, Ohio, United States

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

NCT ID: NCT07136012

This clinical trial is studying a medicine called olpasiran to see if it can help lower the risk of serious heart problems like heart attacks, death from heart disease, or emergency procedures to o...

Recruiting

Phase: PHASE3 Type: interventional Locations: Walnut Creek, California, United States, Tullahoma, Tennessee, United States +54 more

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

NCT ID: NCT02706639

The Williams Syndrome and Supravalvar Aortic Stenosis DNA and Tissue Bank trial is focused on understanding two related conditions: Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS). Wi...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States +3 more

Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention

NCT ID: NCT01927783

The Heart Health Study in Washington D.C. is looking to improve heart health, particularly in the Black community, by creating a weight loss program based in local churches. Researchers will partne...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Drug-Eluting Balloon Treatment vs. Guideline-Directed Medical Therapy for the Treatment of Lipid-Rich Plaques

NCT ID: NCT07107971

This clinical trial is studying a new way to treat certain fatty buildups, called vulnerable plaques, in the heart’s arteries. These plaques can cause serious heart problems by blocking blood flow....

Not yet recruiting

Phase: NA Type: interventional Locations: Amsterdam, Netherlands

Randomized Trial of SGLT2i in Heart Transplant Recipients

NCT ID: NCT06625073

This clinical trial is studying the effects of a medication called empagliflozin in veterans who have received a heart transplant. Heart transplant patients often face challenges with their kidney ...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Nashville, Tennessee, United States, Houston, Texas, United States +4 more

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

NCT ID: NCT07000357

This clinical trial is studying a medication called AZD0780 to see if it can help reduce serious heart-related events in patients who have a history of cardiovascular disease or are at high risk fo...

Recruiting

Phase: PHASE3 Type: interventional Locations: Barcelona, Spain, Montpellier, France +813 more

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

NCT ID: NCT03374215

This clinical trial is focused on understanding the genetic factors that may cause primary aldosteronism, a condition where the adrenal glands produce too much of the hormone aldosterone, leading t...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany

NCT ID: NCT06675552

This clinical trial is focused on improving treatment for patients with heart failure, specifically a type called heart failure with reduced ejection fraction (HFrEF). The study aims to see if a sp...

Recruiting

Type: observational Locations: Leipzig, Germany, Berlin, Germany +4 more

Fish Oil, Metformin and Heart Health in PCOS

NCT ID: NCT06424860

This clinical trial is exploring whether taking fish oil supplements can help improve heart health and insulin levels in women with Polycystic Ovary Syndrome (PCOS). Women with PCOS often have high...

Not yet recruiting

Phase: PHASE1 Type: interventional

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

NCT ID: NCT07087184

This clinical trial is looking at how drinking different types of milk—whole milk (which has more fat) versus skim milk (which has little to no fat)—affects heart health and blood sugar control. Si...

Recruiting

Phase: NA Type: interventional Locations: San Francisco, California, United States

WISE CVD - Continuation (WISE HFpEF)

NCT ID: NCT02582021

The WISE HFpEF trial is studying how certain heart problems, specifically Coronary Microvascular Dysfunction (CMD), affect women who experience chest pain but do not have blocked arteries. Research...

Recruiting

Type: observational Locations: Los Angeles, California, United States

Improving Veteran Referral to Cardiac Rehabilitation

NCT ID: NCT07079358

This study is looking at a new program called the Veterans Cardiac Rehabilitation Referral Program (VCR2P) to see if it helps more Veterans get referred to and attend cardiac rehabilitation after h...

Not yet recruiting

Phase: NA Type: interventional Locations: Nashville, Tennessee, United States, Gainesville, Florida, United States +1 more

The True Face of the Pyramid; Physical Activity Level and Cardiovascular Risk in Patients With Breast Cancer

NCT ID: NCT06837701

This clinical trial, titled "The True Face of the Pyramid," is studying how physical activity affects heart health in women who have survived breast cancer. Cardiovascular disease is a leading caus...

Recruiting

Type: observational Locations: Ankara, State, Turkey

Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)

NCT ID: NCT02543996

This clinical trial is focused on understanding the causes of undiagnosed diseases and cardiovascular disease by collecting blood and tissue samples. Researchers believe that rare genetic changes m...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

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