Clinical Trials for Cardiovascular Disease

Natural History Study of CADASIL

NCT ID: NCT05072483

This clinical trial is studying a genetic condition called CADASIL, which affects blood vessels in the brain and can lead to serious problems like strokes and dementia. The goal is to understand ho...

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

NCT ID: NCT03374215

This clinical trial is focused on understanding the genetic factors that may cause primary aldosteronism, a condition where the adrenal glands produce too much of the hormone aldosterone, leading t...

Impact of Elastin Mediated Vascular Stiffness on End Organs

NCT ID: NCT02840448

This clinical trial is studying how the stiffness of blood vessels in people with Williams Syndrome (WS) and supravalvular aortic stenosis (SVAS) affects different organs in the body, such as the h...

Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)

NCT ID: NCT02543996

This clinical trial is focused on understanding the causes of undiagnosed diseases and cardiovascular disease by collecting blood and tissue samples. Researchers believe that rare genetic changes m...

Cardiology Biobank Registry

NCT ID: NCT00378924

The Cardiology Biobank Registry is a clinical trial aimed at understanding cardiovascular diseases better. The researchers are collecting information from around 12,000 patients who have undergone ...

Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention

NCT ID: NCT01927783

The Heart Health Study in Washington D.C. is looking to improve heart health, particularly in the Black community, by creating a weight loss program based in local churches. Researchers will partne...

Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

NCT ID: NCT03372733

This clinical trial is studying the effects of a special oil rich in Omega-7 fatty acids, specifically palmitoleic acid, on heart health and feelings of fullness in healthy adults. Researchers beli...

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

NCT ID: NCT01316783

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

NCT ID: NCT07000357

This clinical trial is studying a medication called AZD0780 to see if it can help reduce serious heart-related events in patients who have a history of cardiovascular disease or are at high risk fo...

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT ID: NCT07000123

This clinical trial is studying a new medication called AZD0780, which is designed to lower levels of LDL cholesterol (often referred to as "bad" cholesterol) in the blood. The trial is for adults ...

Fish Oil, Metformin and Heart Health in PCOS

NCT ID: NCT06424860

This clinical trial is exploring whether taking fish oil supplements can help improve heart health and insulin levels in women with Polycystic Ovary Syndrome (PCOS). Women with PCOS often have high...

Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany

NCT ID: NCT06675552

This clinical trial is focused on improving treatment for patients with heart failure, specifically a type called heart failure with reduced ejection fraction (HFrEF). The study aims to see if a sp...

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

NCT ID: NCT05440422

This clinical trial, called IFN-CVD, is studying whether a drug named anifrolumab can help improve blood vessel health in people with systemic lupus erythematosus (SLE). People with SLE often face ...

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers

NCT ID: NCT04216342

This clinical trial is studying a new drug called Fx-5A, which researchers believe might help treat heart disease and related inflammation. The main goal is to find out if Fx-5A is safe to use and ...

Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk

NCT ID: NCT05828849

This clinical trial is looking at how a personalized program can help reduce the risk of dying from preventable causes, such as heart attacks, strokes, heavy drinking, and other health issues. The ...

Peers and Technology for Adherence, Access, Accountability, and Analytics (PT4A)

NCT ID: NCT06485700

The PT4A clinical trial is studying a new way to help people with high blood pressure, also known as hypertension, in western Kenya. The researchers want to see if having peers—people from the comm...

Randomized Trial of SGLT2i in Heart Transplant Recipients

NCT ID: NCT06625073

This clinical trial is studying the effects of a medication called empagliflozin in veterans who have received a heart transplant. Heart transplant patients often face challenges with their kidney ...

Technical Development of Cardiovascular Magnetic Resonance Imaging

NCT ID: NCT04927429

This clinical trial is studying new ways to use magnetic resonance imaging (MRI) to better understand and diagnose heart diseases, particularly heart failure, which affects millions of people in th...

The Global Cardiovascular Risk Consortium

NCT ID: NCT05466825

The Global Cardiovascular Risk Consortium (GCVRC) is a large research study looking at how certain risk factors affect heart health and overall survival. The study collects and analyzes data from o...

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

NCT ID: NCT02706639

The Williams Syndrome and Supravalvar Aortic Stenosis DNA and Tissue Bank trial is focused on understanding two related conditions: Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS). Wi...