Clinical Trials for Cholangiocarcinoma

Find clinical trials for cholangiocarcinoma. Discover research opportunities and treatment options in your area.

110 Active Trials Found

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A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

NCT ID: NCT06690281

This clinical trial is studying a new type of treatment called T-cell therapy for patients with advanced gastrointestinal (GI) cancers, such as pancreatic, liver, and colorectal cancers. The goal i...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

NCT ID: NCT06503146

This clinical trial is studying a new imaging method using a special substance called 18F-FAPI-74 to help detect certain types of cancer more effectively. The goal is to find out if this new tracer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma

NCT ID: NCT07030140

This clinical trial is studying a new treatment approach for people with a type of bile duct cancer called hilar cholangiocarcinoma, which is located near where the liver’s bile ducts join. The tri...

Not yet recruiting

Phase: PHASE2 Type: interventional

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

NCT ID: NCT01915225

This clinical trial is focused on collecting tissue samples from patients with certain types of cancer, including colorectal, gastric, bile duct, and pancreas cancers. Researchers need these sample...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

A Study of MGC028 in Participants With Advanced Solid Tumors

NCT ID: NCT06723236

This clinical trial is testing a new treatment called MGC028 for adults with advanced solid tumors, including specific types of lung cancer, bile duct cancer, and pancreatic cancer. The main goals ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +4 more

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

NCT ID: NCT02628067

This clinical trial is studying a medication called pembrolizumab (MK-3475) for people with advanced solid tumors that have not responded to standard treatments. The trial aims to see how well this...

Recruiting

Phase: PHASE2 Type: interventional Locations: North Ryde, , Australia, Midrand, , South Africa +29 more

A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors

NCT ID: NCT05346484

This clinical trial is studying a new treatment called CF33-hNIS (VAXINIA), which is an oncolytic virus designed to target and kill cancer cells, particularly in patients with advanced solid tumors...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Salt Lake City, Utah, United States +11 more

Sequential Anti-Angiogenic Therapy After Immunotherapy in Advanced Biliary Tract Cancer

NCT ID: NCT07025174

This clinical trial is studying a new way to treat advanced biliary tract cancer, which includes cancers of the bile ducts and gallbladder. The researchers want to see if giving patients a type of ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hangzhou, , China

HepQuant: Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer

NCT ID: NCT06899152

The HepQuant study is looking at new ways to measure liver function in patients with liver cancer who are receiving radiation therapy. The researchers want to see if a special type of MRI, which ca...

Recruiting

Phase: NA Type: interventional Locations: Bronx, New York, United States

Bile Omics for Diagnosing Indeterminate Biliary Strictures

NCT ID: NCT07007832

This clinical trial is studying a new way to diagnose certain types of cancer and bile duct problems. Specifically, it focuses on patients with biliary strictures—narrowing of the bile ducts that c...

Recruiting

Type: observational Locations: Shanghai, Shanghai, China, Shanghai, , China

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

NCT ID: NCT05286814

This clinical trial is studying a new treatment approach for patients with specific types of liver cancer, including metastatic colorectal cancer (which has spread to the liver) and intrahepatic ch...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma

NCT ID: NCT05876754

This clinical trial is studying a medication called ivosidenib for patients with advanced cholangiocarcinoma, a type of cancer that affects the bile ducts. Specifically, the trial is looking at whe...

Recruiting

Phase: PHASE3 Type: interventional Locations: Cork, , Ireland, Montpellier, , France +84 more

Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer

NCT ID: NCT06199895

This clinical trial is studying a new treatment called Paclitaxel Polymeric Micelles for Injection. It aims to help patients with advanced cancers, including pancreatic, bile duct, lung, stomach, e...

Recruiting

Phase: PHASE2 Type: interventional Locations: Wuhan, Hubei, China

Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid

NCT ID: NCT06910670

This clinical trial is testing a new online tool designed to help patients with certain rare cancers—specifically cholangiocarcinoma, colorectal cancer, and multiple myeloma—make important decision...

Recruiting

Phase: NA Type: interventional Locations: Saint Louis, Missouri, United States

On-treatment Surveillance of Tumor Evolution and Response to Systemic Treatment in Bile Duct and Liver Cancer

NCT ID: NCT06877637

The BILLIONSTARS study is a research trial aimed at understanding how certain factors influence the response to treatment in patients with bile duct cancer (cholangiocarcinoma) and liver cancer (he...

Recruiting

Type: observational Locations: Kristianstad, , Sweden, Lund, , Sweden +1 more

Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma (LyMIC)

NCT ID: NCT06381648

The clinical trial titled "Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma" is looking to improve how we predict lymph node metastasis (LNM) in patients with a specific type of l...

Recruiting

Type: observational Locations: Duarte, California, United States, Hokkaido, Sapporo, Japan +2 more

Evaluation of Skin Tests in Biotherapy Allergies

NCT ID: NCT06971848

This clinical trial, titled "Evaluation of Skin Tests in Biotherapy Allergies," is studying how to better identify allergic reactions in patients receiving certain biotherapy treatments. Biotherapi...

Not yet recruiting

Phase: NA Type: interventional Locations: Angers, , France

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

NCT ID: NCT04145141

This clinical trial is focused on understanding liver cancer better, specifically two types: hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). Researchers are looking for ways to improve...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, New York, New York, United States +9 more

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

NCT ID: NCT05874414

This clinical trial is studying the safety and effectiveness of a combination of two medications, GNS561 and trametinib, in treating advanced cholangiocarcinoma (a type of cancer affecting the bile...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Buffalo, New York, United States +7 more

High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery

NCT ID: NCT02757859

This clinical trial is studying a new procedure called high volume washing of the abdomen to see if it can help patients with pancreatic cancer live longer after surgery. During this procedure, doc...

Recruiting

Phase: NA Type: interventional Locations: Cleveland, Ohio, United States, Philadelphia, Pennsylvania, United States

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