Clinical Trials for Chordoma

Find clinical trials for chordoma. Discover research opportunities and treatment options in your area.

17 Active Trials Found

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Clinical Genetics Branch Eligibility Screening Survey

NCT ID: NCT07005297

The Clinical Genetics Branch (CGB) is looking for people to participate in research studies focused on specific genetic conditions that can increase the risk of cancer, such as melanoma and various...

Not yet recruiting

Type: observational Locations: Rockville, Maryland, United States

Children and Adults With Chordoma

NCT ID: NCT03910465

This clinical trial is looking at chordoma, which is a rare type of bone cancer that usually develops in the skull or spine. The researchers want to learn more about how chordoma affects patients, ...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

NCT ID: NCT05407441

This clinical trial is studying a combination of three drugs—Tazemetostat, Nivolumab, and Ipilimumab—as a potential treatment for certain types of tumors, including malignant rhabdoid tumor, atypic...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Houston, Texas, United States +1 more

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Chordoma

NCT ID: NCT06787664

This clinical trial is studying a new treatment called BL-B01D1 for patients with locally advanced or metastatic chordoma, a rare type of bone cancer. The main goals of the study are to determine h...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

A Study of ERAS-601 in People With Chordoma

NCT ID: NCT06957327

This clinical trial is studying a new treatment called ERAS-601 for people with chordoma, a rare type of bone cancer that can be difficult to treat. The main goal of the study is to see if ERAS-601...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +5 more

Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone

NCT ID: NCT05033288

This clinical trial is looking at three different treatment options for patients with pelvic bone sarcomas, which are cancers that affect the bones in the pelvic area. The treatments being compared...

Recruiting

Type: observational Locations: Scottsdale, Arizona, United States, Jacksonville, Florida, United States +1 more

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT ID: NCT06625190

This clinical trial is investigating a new treatment approach for certain solid tumors in young patients, including conditions like neuroblastoma and rhabdomyosarcoma. The treatment involves using ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Gainesville, Florida, United States

Pembrolizumab and Pemetrexed for Progressive Chordoma

NCT ID: NCT06794645

This clinical trial is exploring the combination treatment of two medications, pembrolizumab and high-dose pemetrexed, for patients with chordoma, a rare type of bone cancer. The main goal is to se...

Recruiting

Phase: PHASE2 Type: interventional Locations: Santa Monica, California, United States

Descriptive Cohort of French Patients Treated with Carbonetherapy Since October 2010 Outside PHRC-ETOILE

NCT ID: NCT06535997

This clinical trial is examining the use of carbonetherapy, a special type of radiation treatment, for patients with certain hard-to-treat cancers that are often difficult to operate on or resistan...

Not yet recruiting

Type: observational Locations: Caen, , France, Grenoble, , France

Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease

NCT ID: NCT02986516

This clinical trial is comparing two treatment options for patients with sacral chordoma, a type of cancer that occurs in the bone at the base of the spine. The study is looking at how effective su...

Recruiting

Phase: NA Type: interventional Locations: Leiden, , Netherlands, Budapest, , Hungary +27 more

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy

NCT ID: NCT06029218

This clinical trial is exploring the effects of a new way to deliver proton therapy for certain types of cancers, including chordoma, chondrosarcoma, Ewing sarcoma, and osteosarcoma. Specifically, ...

Recruiting

Phase: NA Type: interventional Locations: Nice, , France

Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma

NCT ID: NCT05041127

This clinical trial is studying a medication called cetuximab to see if it can help patients with advanced chordoma, a rare type of cancer that can be difficult to treat when it cannot be removed b...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.

NCT ID: NCT03242382

This clinical trial is studying the effects of a medication called Palbociclib in patients with advanced types of sarcomas, specifically soft-tissue sarcoma, osteosarcoma, and chordoma. The main go...

Recruiting

Phase: PHASE2 Type: interventional Locations: Madrid, , Spain, Madrid, , Spain +17 more

Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas

NCT ID: NCT04832620

This clinical trial is studying the use of advanced imaging techniques to better understand and treat two types of bone tumors called chordomas and chondrosarcomas, which often occur in the spine a...

Recruiting

Type: observational Locations: Delft, South Holland, Netherlands, Leiden, South Holland, Netherlands

Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma

NCT ID: NCT06140732

This clinical trial is studying a new treatment for advanced chordoma, a type of bone cancer that can spread to other parts of the body. Researchers want to see how well two drugs, Camrelizumab and...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base

NCT ID: NCT05861245

This clinical trial is looking at a new way to treat specific types of tumors called chordomas and chondrosarcomas, which occur at the base of the skull. Researchers want to see how effective and s...

Recruiting

Phase: NA Type: interventional Locations: Madrid, , Spain

Long-Term Longitudinal QoL in Patients Undergoing EEA

NCT ID: NCT04087902

This clinical trial is looking at how patients feel after having surgery to remove tumors or other growths from the base of the skull using a special technique called endonasal endoscopic surgery. ...

Recruiting

Type: observational Locations: Columbus, Ohio, United States

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