Clinical Trials for Cystic Fibrosis

Sinus Disease in Young Children With Cystic Fibrosis

NCT ID: NCT06191640

This clinical trial is studying how a new type of treatment called highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators affects young children with cystic fibrosis...

A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis

NCT ID: NCT06478706

This clinical trial is testing a new inhaled medication called ETD001 in people with cystic fibrosis (CF). The study has two parts. In the first part, researchers want to see if ETD001 is safe for ...

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

NCT ID: NCT05422222

This clinical trial is looking at a new treatment called VX-121/tezacaftor/deutivacaftor for young patients with cystic fibrosis (CF), a condition that affects the lungs and digestive system. The s...

Diagnosis and Treatment of Patients With Cystic Fibrosis

NCT ID: NCT00001223

This clinical trial is focused on understanding cystic fibrosis (CF), a genetic condition that can lead to issues with the lungs, liver, pancreas, and diabetes. The goal of the study is to collect ...

A Phase 1 Study Evaluating Safety and Tolerability of RCT2100 in Healthy Participants and in Participants With CF

NCT ID: NCT06237335

This clinical trial is testing a new drug called RCT2100 to see if it is safe and well-tolerated in both healthy adults and those with cystic fibrosis (CF). This is the first time RCT2100 is being ...

Natural History of Bronchiectasis

NCT ID: NCT00943514

This clinical trial is studying bronchiectasis, a condition where the airways in the lungs become inflamed and damaged, leading to repeated respiratory infections. The researchers aim to understand...

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

NCT ID: NCT06654752

The STOP PEDS trial is researching how effective and safe two different antibiotic treatments are for children and teenagers with cystic fibrosis (CF) who are experiencing lung infections. This stu...

Exercise in Child Health

NCT ID: NCT05359991

The "Exercise in Child Health" clinical trial is studying how children with certain chronic illnesses—like cystic fibrosis, sickle cell disease, and those who have had SARS-CoV-2 infections—respond...

Muscle Endurance in Children With Cystic Fibrosis

NCT ID: NCT06812793

This clinical trial is studying how well children with cystic fibrosis (CF) can use their muscles, especially the muscles involved in breathing and those in the core and legs. CF is a genetic condi...

Natural History of Noncirrhotic Portal Hypertension

NCT ID: NCT02417740

The clinical trial titled "Natural History of Noncirrhotic Portal Hypertension" aims to better understand a condition called Noncirrhotic Portal Hypertension (NCPH), which occurs when there is incr...

Comparative Effects of Mechanical and Manual Airway Clearance Techniques in Cystic Fibrosis

NCT ID: NCT07062939

This clinical trial is studying two different ways to help clear the lungs in people with cystic fibrosis, a condition that causes thick mucus to build up in the lungs. The researchers want to find...

Role of Genetic Factors in the Development of Lung Disease

NCT ID: NCT00001532

This clinical trial is looking at how our genes might affect the development of various lung diseases, including cystic fibrosis, asthma, and pulmonary fibrosis. Researchers will examine lung cells...

Remote Sputum Collection in Cystic Fibrosis

NCT ID: NCT06950892

This clinical trial is looking at how well home-collected sputum samples can help diagnose lung infections in people with cystic fibrosis (CF). Normally, sputum is mucus that comes from the lungs, ...

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older

NCT ID: NCT06460506

Assessing Tenapanor as a Treatment of CF-related Constipation.

NCT ID: NCT06810167

This clinical trial is studying a medication called tenapanor to see if it can help patients with cystic fibrosis (CF) who also experience constipation related to their condition. Tenapanor is alre...

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

NCT ID: NCT06683092

The RETRIAL study is looking at how people with Cystic Fibrosis (CF) can safely restart a new medication called vanzacaftor/tezacaftor/deutivacaftor (VTD) after experiencing mental health issues or...

A Study to Investigate the Safety and Tolerability of Single and Multiple Ascending Doses of KIT2014 in Healthy Subjects

NCT ID: NCT06659757

This clinical trial is studying a new medication called KIT2014 to see how safe it is and how well it is tolerated by healthy volunteers. The goal is to gather important information about how the m...

A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Study With BI 3720931 (Lenticlair™-ON)

NCT ID: NCT06962852

This clinical trial is designed to monitor the long-term health of people with cystic fibrosis who participated in a previous study involving a medicine called BI 3720931 (also known as Lenticlair™...

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

NCT ID: NCT06154447

This clinical trial is testing a new drug called VX-828 to see how safe it is and how the body handles it in healthy people. The goal is to gather important information that can help in the future ...

Prospective Analysis of Urine LAM to Eliminate NTM Sputum Screening

NCT ID: NCT04579211