Clinical Trials for Cystic Fibrosis

Diagnosis and Treatment of Patients With Cystic Fibrosis

NCT ID: NCT00001223

This clinical trial is focused on understanding cystic fibrosis (CF), a genetic condition that can lead to issues with the lungs, liver, pancreas, and diabetes. The goal of the study is to collect ...

Pharmacokinetics of CFTR Modulators in Pregnant Individuals and in Postpartum Breastfeeding Mothers

NCT ID: NCT04940533

This clinical trial is studying how the body processes certain medications used to treat cystic fibrosis during pregnancy and after giving birth. Specifically, it will look at how these medications...

Natural History of Noncirrhotic Portal Hypertension

NCT ID: NCT02417740

The clinical trial titled "Natural History of Noncirrhotic Portal Hypertension" aims to better understand a condition called Noncirrhotic Portal Hypertension (NCPH), which occurs when there is incr...

Sinus Disease in Young Children With Cystic Fibrosis

NCT ID: NCT06191640

This clinical trial is studying how a new type of treatment called highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators affects young children with cystic fibrosis...

Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF

NCT ID: NCT05639556

This clinical trial is looking into how nutrition and body composition affect lung function in adults with cystic fibrosis (CF). The researchers want to understand different ways to measure body he...

A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis

NCT ID: NCT06159725

This clinical trial is studying a new treatment called CMTX-101, which is designed to help people with cystic fibrosis (CF) who are dealing with persistent lung infections. CMTX-101 is a type of me...

Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

NCT ID: NCT05844449

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

NCT ID: NCT06654752

The STOP PEDS trial is researching how effective and safe two different antibiotic treatments are for children and teenagers with cystic fibrosis (CF) who are experiencing lung infections. This stu...

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

NCT ID: NCT06747858

This clinical trial is studying a new treatment called ARCT-032 for adults with Cystic Fibrosis (CF), a genetic condition that affects the lungs and digestive system. The trial focuses on people wh...

A Phase 1 Study Evaluating Safety and Tolerability of RCT2100 in Healthy Participants and in Participants With CF

NCT ID: NCT06237335

This clinical trial is testing a new drug called RCT2100 to see if it is safe and well-tolerated in both healthy adults and those with cystic fibrosis (CF). This is the first time RCT2100 is being ...

A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Study With BI 3720931 (Lenticlair™-ON)

NCT ID: NCT06962852

This clinical trial is designed to monitor the long-term health of people with cystic fibrosis who participated in a previous study involving a medicine called BI 3720931 (also known as Lenticlair™...

Genetics of Insulin and Incretins in Cystic Fibrosis

NCT ID: NCT01852448

This clinical trial is focused on understanding how genetics may influence the development of diabetes in people with cystic fibrosis, a condition known as cystic fibrosis-related diabetes (CFRD). ...

Lung Transplant READY CF 2: A Multi-site RCT

NCT ID: NCT06030206

The Lung Transplant READY CF 2 trial is studying how to help people with cystic fibrosis (CF) better understand lung transplants as a treatment option for severe lung disease. Many individuals with...

Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF)

NCT ID: NCT04002882

The ORBIT-CF trial is studying how body fat distribution and nutrition impact the health of young people with cystic fibrosis (CF), particularly focusing on their lung function and how their bodies...

A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis

NCT ID: NCT06478706

This clinical trial is testing a new inhaled medication called ETD001 in people with cystic fibrosis (CF). The study has two parts. In the first part, researchers want to see if ETD001 is safe for ...

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

NCT ID: NCT05422222

This clinical trial is looking at a new treatment called VX-121/tezacaftor/deutivacaftor for young patients with cystic fibrosis (CF), a condition that affects the lungs and digestive system. The s...

Natural History of Bronchiectasis

NCT ID: NCT00943514

This clinical trial is studying bronchiectasis, a condition where the airways in the lungs become inflamed and damaged, leading to repeated respiratory infections. The researchers aim to understand...

Exercise in Child Health

NCT ID: NCT05359991

The "Exercise in Child Health" clinical trial is studying how children with certain chronic illnesses—like cystic fibrosis, sickle cell disease, and those who have had SARS-CoV-2 infections—respond...

Comparative Effects of Mechanical and Manual Airway Clearance Techniques in Cystic Fibrosis

NCT ID: NCT07062939

This clinical trial is studying two different ways to help clear the lungs in people with cystic fibrosis, a condition that causes thick mucus to build up in the lungs. The researchers want to find...

Muscle Endurance in Children With Cystic Fibrosis

NCT ID: NCT06812793

This clinical trial is studying how well children with cystic fibrosis (CF) can use their muscles, especially the muscles involved in breathing and those in the core and legs. CF is a genetic condi...