Clinical Trials for Immune System Diseases

Find clinical trials for immune system diseases. Discover research opportunities and treatment options in your area.

22 Active Trials Found

Showing 22 trials on this page

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Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

NCT ID: NCT02579967

This clinical trial is studying the use of stem cell transplants from healthy donors to help treat people with serious immune system problems, specifically primary immunodeficiencies. These conditi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States +2 more

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

NCT ID: NCT03922724

This clinical trial is studying a treatment called allogeneic hematopoietic cell transplantation, which is a type of blood cell transplant, for people with peripheral T-cell lymphoma, a form of blo...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States, Minneapolis, Minnesota, United States

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

NCT ID: NCT04339777

This clinical trial is investigating the use of blood stem cell transplants to treat people with certain immune system disorders, particularly those who have not responded to standard treatments. T...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

NCT ID: NCT00001406

This clinical trial is studying eosinophils, which are a type of white blood cell that can increase in number due to allergies, asthma, and certain infections. The researchers want to understand ho...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Abrocitinib Taiwan Treatment Pattern and Real World Study in ATopiC Dermatitis (ATTRACT Registry)

NCT ID: NCT06353087

The ATTRACT Registry study is looking at how patients with moderate-to-severe atopic dermatitis (a type of eczema) are treated with a medication called abrocitinib over the course of 12 months. The...

Recruiting

Type: observational Locations: Taipei, , Taiwan, Taipei, , Taiwan +6 more

Clonal Hematopoiesis of Immunological Significance

NCT ID: NCT05969821

This clinical trial, titled "Clonal Hematopoiesis of Immunological Significance," is focused on understanding certain immune system diseases and conditions, particularly those linked to a syndrome ...

Not yet recruiting

Type: observational

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

NCT ID: NCT00006150

This clinical trial is focused on studying Hyper IgE Recurrent Infection Syndrome (HIES), a condition that affects the immune system and leads to frequent skin and lung infections, as well as other...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

HIV Engagement and Adolescent Depression Support (HEADS-UP)

NCT ID: NCT06173544

The HIV Engagement and Adolescent Depression Support (HEADS-UP) trial is a study aimed at helping teenagers who are living with HIV and may also be dealing with depression or anxiety. The study wil...

Recruiting

Phase: NA Type: interventional Locations: Lilongwe, , Malawi, Lilongwe, , Malawi +3 more

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

NCT ID: NCT03016377

This clinical trial is studying a new treatment for patients with relapsed or refractory acute lymphoblastic leukemia (ALL), a type of blood cancer. The treatment involves modifying a patient’s own...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chapel Hill, North Carolina, United States

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

NCT ID: NCT05787574

This clinical trial is investigating whether two treatments, emapalumab or a combination of fludarabine and dexamethasone, can help reduce inflammation in people with specific immune system disorde...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +9 more

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

NCT ID: NCT03696784

This clinical trial is investigating a new treatment for patients with certain types of B-cell lymphoma, which is a cancer affecting the immune system. The treatment combines two approaches: modify...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chapel Hill, North Carolina, United States

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

NCT ID: NCT03602157

This clinical trial is studying a new type of treatment for certain types of lymphoma, which is a cancer of the immune system. The treatment involves using specially modified T cells (a type of whi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chapel Hill, North Carolina, United States

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

NCT ID: NCT02690545

This clinical trial is studying a new treatment for patients with certain types of lymphoma, specifically those whose cancer has come back or has not responded to previous treatments. The treatment...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chapel Hill, North Carolina, United States

Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care

NCT ID: NCT05910840

This clinical trial is looking at how an online training and peer support platform, called Support-t, can help teenagers with Type 1 Diabetes (T1D) prepare for the transition to adult healthcare. T...

Recruiting

Phase: NA Type: interventional Locations: Sherbrooke, , Canada, Québec, , Canada +2 more

The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)

NCT ID: NCT06291415

This clinical trial is studying a new treatment called HMPL-523 for adults with a condition known as Immune Thrombocytopenia (ITP). ITP is a blood disorder where the body doesn't have enough platel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Adelaide, , Australia +26 more

Digital Diagnostics and Intervention Services for Parkinson's Disease

NCT ID: NCT06534177

This clinical trial is studying new digital tools to help assess and improve the movement of people with Parkinson's disease. Currently, patients see their doctors only once every 12 to 18 months, ...

Not yet recruiting

Type: observational

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

NCT ID: NCT06271252

The RIGEL Study is a clinical trial designed to test a new treatment called OriCAR-017 for patients with relapsed or refractory multiple myeloma, which is a type of blood cancer. This is the first ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

NCT ID: NCT05565248

This clinical trial is studying a new treatment called VCTX211, which is designed to help people with Type 1 Diabetes (T1D). The main goals of the study are to see how safe the treatment is, how we...

Recruiting

Phase: PHASE1 Type: interventional Locations: Edmonton, Alberta, Canada, Vancouver, British Columbia, Canada

Epigenetic Memory of Vitamin D Supplementation

NCT ID: NCT06104111

This clinical trial, titled "Epigenetic Memory of Vitamin D Supplementation," is exploring how vitamin D3, a nutrient found in some foods and supplements, can influence our immune system at a cellu...

Recruiting

Phase: PHASE1 Type: interventional Locations: Olsztyn, , Poland

Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms

NCT ID: NCT06065592

This clinical trial is studying how certain biological markers and genetic variations relate to blood clots that can occur in people with cancer, especially those with colorectal cancer. The resear...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tripoli, North Lebanon, Lebanon, Tripoli, North Lebanon, Lebanon

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