Clinical Trials for Liver Failure

Find clinical trials for liver failure. Discover research opportunities and treatment options in your area.

21 Active Trials Found

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The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial

NCT ID: NCT06871111

The MARCO Trial is a clinical study designed to explore a new treatment for patients who are hospitalized due to serious liver conditions, such as liver failure or cirrhosis. This trial will test a...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

NCT ID: NCT04617522

This clinical trial is studying a new medication called sacituzumab govitecan-hziy for people with advanced or metastatic solid tumors who also have moderate liver problems. The main goals are to f...

Recruiting

Phase: PHASE1 Type: interventional Locations: Baltimore, Maryland, United States, Lyon, , France +8 more

Efficacy and Safety of Citrate Anticoagulation in CRRT for Patients With Liver Failure/DysfuncTION, the CAUTION Trial! A Retrospective Study on Etiology of Liver Failure and Their Complications

NCT ID: NCT06908746

The CAUTION Trial is a study looking at how well a special kind of blood thinner called citrate works for patients with liver failure who also have acute kidney injury (AKI) and are critically ill....

Recruiting

Type: observational Locations: Edegem, Antwerp, Belgium

Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver Failure

NCT ID: NCT06904755

This clinical trial is studying a new treatment for adults with liver failure using a special kind of cell called mesenchymal stem cells, which help with blood purification. The main goal is to see...

Recruiting

Phase: PHASE1 Type: interventional Locations: Guangzhou, Guangdong, China

Empagliflozin in Patients With Cirrhosis and Ascites

NCT ID: NCT05726032

This clinical trial is studying a medication called empagliflozin to see how it affects patients with cirrhosis and ascites, which is a condition where fluid builds up in the abdomen due to liver p...

Recruiting

Phase: PHASE2 Type: interventional Locations: New Haven, Connecticut, United States

The Safety ,Tolerability and Efficacy Study of HepaCure in Chinese Subjects with Acute-On-Chronic Liver Failure

NCT ID: NCT05989958

This clinical trial is investigating a new treatment called HepaCure, which is a type of bio-artificial liver support system. The study aims to see if HepaCure, when used alongside a standard treat...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China, Beijing, Beijing, China

MSC-EVs in Acute/ Acute-on-Chronic Liver Failure After Liver Transplantation

NCT ID: NCT06825572

This clinical trial is investigating the use of a new treatment called MSC-EVs (mesenchymal stem cell-derived extracellular vesicles) for patients experiencing acute-on-chronic liver failure after ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Guangzhou, Guangdong, China

Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia

NCT ID: NCT04447911

This clinical trial is studying the effects of a medication called empagliflozin (Jardiance)® on patients who have low sodium levels in their blood, a condition known as hyponatremia. Hyponatremia ...

Recruiting

Phase: PHASE4 Type: interventional Locations: Basel, , Switzerland, Luzern, , Switzerland +1 more

Study of Oxidized Albumin in Liver Transplant Patients

NCT ID: NCT06772298

This clinical trial is studying the changes in a protein called albumin in patients who are undergoing a liver transplant. Albumin plays an important role in the body, and the trial aims to underst...

Not yet recruiting

Type: observational

NOninVasive Intracranial PrEssure from Transcranial DoppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients

NCT ID: NCT04548596

This clinical trial is studying how to better monitor brain health in patients who have suffered serious injuries or conditions affecting the brain, such as traumatic brain injury, strokes, or blee...

Recruiting

Type: observational Locations: San Francisco, California, United States, Atlanta, Georgia, United States +2 more

Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCC

NCT ID: NCT05484908

This clinical trial is looking at how well an artificial liver support system (ALSS) can help patients with liver failure caused by immune checkpoint inhibitor treatments for liver cancer, specific...

Recruiting

Phase: NA Type: interventional Locations: Guangzhou, Guangdong, China

Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients

NCT ID: NCT05744635

This clinical trial is looking at how different medications containing tacrolimus work in liver transplant patients. It aims to understand how well these medications are absorbed and used by the bo...

Recruiting

Type: observational Locations: Budapest, , Hungary, Ljubljana, , Slovenia

Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver Failure

NCT ID: NCT06224023

This clinical trial is studying a substance called presepsin to see how well it can predict certain health outcomes in patients with ascites related to chronic liver failure. Ascites is the buildup...

Recruiting

Type: observational Locations: Bucharest, , Romania

Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy

NCT ID: NCT06532214

This clinical trial is looking at the complications that can happen after a liver surgery called hepatectomy, which is often used to treat conditions like liver cancer and other liver issues. While...

Recruiting

Type: observational Locations: Guangzhou, , China, Guangzhou, Guangdong, China

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients

NCT ID: NCT05234190

This clinical trial is studying a new treatment called QEL-001, which aims to help people who have received a liver transplant. Specifically, the trial is looking at how safe and effective QEL-001 ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brussels, , Belgium, Leuven, , Belgium +8 more

Fecal Microbiota Transplantation for Liver Failure

NCT ID: NCT05170971

This clinical trial is exploring a treatment called fecal microbiota transplantation (FMT) for people with liver failure. FMT involves taking healthy bacteria from a donor's stool and placing it in...

Recruiting

Phase: NA Type: interventional Locations: Ningbo, Zhejiang, China

A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With Infection

NCT ID: NCT06272071

This clinical trial is looking at patients with severe hepatitis, also known as liver failure, especially those who are dealing with infections at the same time. The main goal is to better understa...

Not yet recruiting

Type: observational

Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose

NCT ID: NCT05517668

This clinical trial is looking at the effectiveness of a medication called fomepizole in treating patients who have taken too much acetaminophen, which can harm the liver. The researchers want to f...

Recruiting

Phase: PHASE2 Type: interventional Locations: Denver, Colorado, United States

Quantitative MRI and Outcomes of Liver Resection

NCT ID: NCT06181318

This clinical trial is looking at a special type of MRI called multiparametric MRI to help doctors better understand how a patient’s liver will function after major liver surgery, known as liver re...

Not yet recruiting

Type: observational

Alterations in Coagulation Factor Levels in Patients With End Stage Liver Disease

NCT ID: NCT06014320

This clinical trial is looking to better understand how certain blood proteins, called coagulation factors VIII and IX, change in patients who are going through liver transplantation due to severe ...

Not yet recruiting

Type: observational Locations: Palo Alto, California, United States

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