Clinical Trials for Metabolic Diseases

A Phase 3 Study of NTLA-2001 in ATTRv-PN

NCT ID: NCT06672237

This clinical trial is testing a new treatment called NTLA-2001 for people with a condition known as ATTRv-PN, which is a type of nerve disorder caused by the buildup of abnormal proteins in the bo...

The Effect of Processing on Food Reward

NCT ID: NCT06017986

This clinical trial is studying how different types of processed foods affect our bodies and brains, particularly in relation to metabolic responses and food preferences. Researchers want to find o...

The Efficacy and Safety of Puerarin in Obesity Treatment

NCT ID: NCT06968208

This clinical trial is studying a treatment called puerarin to see if it can help people with obesity lose weight and improve their metabolism. The researchers are looking for adults aged 18 to 60 ...

The SWITCH Dietary and Behavioural Intervention Study

NCT ID: NCT06973408

The SWITCH Dietary and Behavioural Intervention Study is a research project aimed at understanding how different types of dietary support can improve health and well-being. The study will involve 3...

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

NCT ID: NCT06003153

The GLUCOSE-MGH trial is researching how genetic differences affect how people respond to a medication called oral semaglutide, which is used to treat type 2 diabetes. The study involves participan...

Cardiometabolic evalUation REgistry of Heart Failure

NCT ID: NCT06939985

This clinical trial, called the Cardiometabolic Evaluation Registry of Heart Failure, is studying how different health factors related to metabolism and heart function affect patients with heart fa...

Magnetic Resonance Imaging in Metabolic Diseases

NCT ID: NCT06709846

This clinical trial is studying how brain imaging, specifically using magnetic resonance imaging (MRI), can help us understand differences in the brains of people with metabolic diseases compared t...

Effect of Low Valine Diet on Body Weight and Metabolic Parameters

NCT ID: NCT06883578

This clinical trial is studying how a low-valine diet affects body weight and metabolic health in people who are overweight or have metabolic-related conditions, like fatty liver disease. The resea...

Financial Navigation and Peer Support to Improve Diabetes Outcomes

NCT ID: NCT06619834

This clinical trial is looking at a new way to help people with diabetes manage their condition and the financial burdens that come with it. The study is testing a combined approach that includes f...

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

NCT ID: NCT06674980

This clinical trial is looking at how well certain human placental membrane products work alongside standard treatment for people with nonhealing diabetic foot ulcers (DFUs) and venous leg ulcers (...

Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc

NCT ID: NCT05236374

This clinical trial is looking at how eating beef as part of a heart-healthy diet might help the body absorb zinc better. Zinc is an important mineral that helps with many body functions, including...

Relationship Between Metabolic Profiles and Chronic Diseases and Neoplasms

NCT ID: NCT06524037

This clinical trial is studying how metabolic disorders, which are conditions that affect how our bodies process food and energy, may be linked to chronic diseases (like diabetes or heart disease) ...

Genetic and Metabolic Disease in Children

NCT ID: NCT02650622

This clinical trial is studying genetic and metabolic diseases in children to find new genes that may cause these conditions. The researchers aim to identify specific mutations (or changes in genes...

Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity

NCT ID: NCT06425042

This clinical trial is studying the effects of a supplement called nicotinamide riboside (NR), along with exercise, to see if it can help improve health as we age. Researchers believe that boosting...

Molecular Signature of Inactivity Induced Exercise Responsiveness

NCT ID: NCT06301243

This clinical trial is studying how a day of sitting a lot affects our muscles and how they respond to exercise. Researchers want to understand if being inactive for a day impacts the way our bodie...

A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II

NCT ID: NCT05208281

This clinical trial is studying a new treatment called GNR-055 for patients with Mucopolysaccharidosis Type II, also known as Hunter syndrome. The goal is to find out how safe the treatment is, how...

Evaluation of Capillary Blood Collection Devices (Mitra® and HemaPEN®)

NCT ID: NCT05894122

This clinical trial is studying two blood collection devices called Mitra® and HemaPEN®, which are typically used in other areas of medicine but are being tested for children with a condition calle...

Brain Substrate Switch to Ketones and Lactate

NCT ID: NCT06000605

This clinical trial is studying how the brain uses different fuels, like sugars and fats, to stay active, especially during fasting or intense exercise. The researchers want to find out if switchin...

Study to Create Potential Cell-Based Therapies to Treat Human Disease and Disability

NCT ID: NCT00628199

Epigenetic Mechanisms and Severe Obesity (Biological Tissue Collection)

NCT ID: NCT02663388

This clinical trial, titled "Epigenetic Mechanisms and Severe Obesity," is studying how vitamin levels and genetic changes (called epigenetic mechanisms) affect serious complications related to obe...