Clinical Trials for Mild Cognitive Impairment

Software Validation Study-Cognitive Status Indicator

NCT ID: NCT06809725

The SPARK Cognitive Status Indicator study is testing new software designed to help assess cognitive health, particularly for conditions like Alzheimer’s disease, mild cognitive impairment, and dem...

Everyday Memory Impairment in PD-related Cognitive Decline

NCT ID: NCT04474379

This clinical trial is studying memory problems that can happen in people with Parkinson’s disease, especially those who have mild difficulties with thinking and memory but do not have dementia. Th...

Senicapoc in Alzheimer's Disease

NCT ID: NCT04804241

This clinical trial is studying a new medication called Senicapoc to see if it can help people in the early stages of Alzheimer's disease, specifically those with mild cognitive impairment or mild ...

Longitudinal Early-onset Alzheimer's Disease Study Protocol

NCT ID: NCT03507257

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) is a research study that aims to understand how early onset Alzheimer's disease and related conditions progress over time. The study i...

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

NCT ID: NCT06584357

The Bio-Hermes-002 clinical trial is studying how certain biological markers found in blood and digital data relate to brain imaging results in older adults. This research includes participants who...

Improvement of Memory in Mild Cognitive Impairment

NCT ID: NCT05708001

This clinical trial is studying a treatment called transcranial alternating current stimulation (tACS) to see if it can help improve memory in older adults who have mild cognitive impairment (MCI)....

MCI Speech in Noise

NCT ID: NCT06102486

This clinical trial, called "MCI Speech in Noise," is studying how well people with Mild Cognitive Impairment (MCI) can hear soft sounds and how their brains understand these sounds compared to hea...

Understanding Brain Mechanisms Involved in Autobiographical Memory

NCT ID: NCT05710549

This clinical trial is focused on understanding how our brains work when we remember personal experiences, a process known as autobiographical memory. Researchers want to learn about the brain's ac...

Olfactory Training in Mild Cognitive Impairment

NCT ID: NCT06825403

This clinical trial is investigating a treatment called Olfactory Training to see if it can help improve the sense of smell and thinking abilities in people with Mild Cognitive Impairment (MCI). MC...

Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges

NCT ID: NCT06347172

This clinical trial is looking at a method called "deprescribing," which means reducing or stopping certain medications that may not be helpful or could be harmful for people living with dementia. ...

MIBG in Aging and Neurologic Disorders

NCT ID: NCT05514106

The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study

NCT ID: NCT05574400

The CAPACHINOS-2 Study is looking at how caffeine might help patients recover better after major surgery. Researchers want to see if giving caffeine can reduce the chances of developing postoperati...

Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI

NCT ID: NCT06935812

This clinical trial is studying how different types of exercises can help improve cognitive function in people with Mild Cognitive Impairment (MCI), a condition that affects memory and thinking ski...

White Matter Hyperintensities in Amnestic Mild Cognitive Impairment or Alzheimer's Disease

NCT ID: NCT06179680

This clinical trial is exploring the presence of white matter hyperintensities in the brains of individuals with amnestic mild cognitive impairment (aMCI) or Alzheimer's disease. White matter hyper...

Breathing, Relaxation, Attention Training, & Health in Older Adults (BREATHE)

NCT ID: NCT04522791

The BREATHE trial is studying a new approach to help older adults with mild cognitive impairment (MCI), which is a condition that can affect memory and thinking skills. Researchers want to see if c...

Telerehabilitation of Balance Clinical and Economic Decision Support System

NCT ID: NCT06534164

This clinical trial, called the TeleRehabilitation of Balance Clinical and Economic Decision Support System (TeleRehab DSS), is studying a new way to help older adults and individuals with specific...

rTMS for Apathy Clinical Trial

NCT ID: NCT05561205

This clinical trial is exploring the use of a treatment called repetitive transcranial magnetic stimulation (rTMS) to help improve apathy in people with Alzheimer's disease. Apathy is when someone ...

A Study of NTRX-07 in Participants With Alzheimer's Disease

NCT ID: NCT07058688

This clinical trial is studying a new medicine called NTRX-07, which is being tested in people with mild cognitive impairment (MCI) or mild to moderate Alzheimer’s disease (AD). The main goal is to...

Spatial Memory Training and Cognitive Function

NCT ID: NCT07002996

This clinical trial is studying whether a special memory training program can help improve memory and brain function in people with Mild Cognitive Impairment (MCI). MCI is a condition where individ...

Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers

NCT ID: NCT07041450

This study is looking at a new way to screen people who may have early signs of Alzheimer’s disease or related memory problems. The goal is to use easy-to-do digital tests and simple blood tests to...