Clinical Trials for Multiple Sclerosis

A Specialized Diet for Multiple Sclerosis

NCT ID: NCT07033975

This clinical trial is studying whether following a Mediterranean diet—known for being rich in fruits, vegetables, and healthy fats—can help people with multiple sclerosis (MS). MS is a condition w...

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

NCT ID: NCT06141486

This clinical trial is studying a new medication called frexalimab to see if it can help adults with a type of multiple sclerosis known as non-relapsing secondary progressive multiple sclerosis (nr...

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT ID: NCT06141473

This clinical trial is studying the effectiveness and safety of a medication called frexalimab (also known as SAR441344) for adults who have relapsing forms of multiple sclerosis (MS). The goal is ...

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

NCT ID: NCT06735248

This clinical trial is looking at a new treatment called mRNA-1195 to see if it can help prevent relapses in people with early multiple sclerosis (MS). The study aims to understand how safe the tre...

Deciphering Preserved Autonomic Function After Multiple Sclerosis

NCT ID: NCT07012135

This clinical trial is studying how multiple sclerosis (MS) affects the autonomic nervous system, which controls important bodily functions like blood pressure, blood flow to the skin, and bladder ...

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

NCT ID: NCT00794352

This clinical trial is studying how the immune system may affect diseases of the brain and spinal cord, particularly conditions like multiple sclerosis. Researchers want to better understand how im...

Reliability and Validity of the Turkish Version of General Sleep Disturbance Scale (GSDS-T) in Multiple Sclerosis

NCT ID: NCT06875908

This clinical trial is studying a tool called the General Sleep Disturbance Scale (GSDS-T) which helps to measure sleep problems in people with Multiple Sclerosis (MS). The researchers want to see ...

Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)

NCT ID: NCT00001248

This clinical trial is studying the effects of Multiple Sclerosis (MS) through Magnetic Resonance Imaging (MRI) and other tests. It aims to understand how MS progresses in patients who are untreate...

A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 in Participants With Multiple Sclerosis.

NCT ID: NCT05704361

This clinical trial is investigating a new treatment called RO7121932 for people with Multiple Sclerosis (MS). The main goal is to see how safe the treatment is and how well the body processes it w...

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

NCT ID: NCT03109288

The TRAP-MS clinical trial is studying how different medications can help manage multiple sclerosis (MS) by targeting inflammation in the brain and spinal fluid. Researchers want to find out if cha...

Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders

NCT ID: NCT05982925

This clinical trial is studying how certain diseases, like Multiple Sclerosis (MS) and Neuromyelitis Optica, affect the brain and spinal cord over time. Researchers will use MRI scans, blood tests,...

Clinical Impact Through AI-assisted MS Care - A Prospective Multi-center Study

NCT ID: NCT07032246

This clinical trial, called PROCLAIM, is looking at how using a special type of brain scan analysis—called quantitative brain MRI with the icobrain mr software—can help doctors better detect diseas...

An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment

NCT ID: NCT06675955

This clinical trial is an extension study for people with Multiple Sclerosis (MS) who are currently receiving treatment with a medication called ocrelizumab. The main goals of this study are to und...

Feasibility of a Vocational Rehabilitation Intervention for Job Retention in Workers With MS-RiaLSM Intervention Project

NCT ID: NCT06805318

This clinical trial is studying a program designed to help people with Multiple Sclerosis (MS) keep their jobs. MS is a disease that affects the nervous system and can make it hard for people to wo...

A Phase IIa Study of Vitamin D3 Tolerogenic Dendritic Cells (tolDC) for Multiple Sclerosis

NCT ID: NCT07020715

This clinical trial is studying a new treatment approach for people with multiple sclerosis (MS) using specially prepared immune cells called tolerogenic dendritic cells (tolDC). These cells are cr...

Screening for Cognitive Disorders in Multiple Sclerosis

NCT ID: NCT07030036

This study is looking at how multiple sclerosis (MS) can affect thinking skills like memory, how fast you think, and understanding space around you. These changes can make daily activities and work...

A Pilot Randomized Controlled Trial: CoINTEGRATE

NCT ID: NCT05732285

The CoINTEGRATE trial is a research study aimed at exploring a new approach to help individuals with neurocognitive disorders, such as traumatic brain injury, multiple sclerosis, and mild cognitive...

Effects of Mat and Reformer Pilates in Multiple Sclerosis

NCT ID: NCT06931522

This clinical trial is studying how two types of Pilates—Mat Pilates and Equipment-Based Pilates—can help people with Multiple Sclerosis (MS) improve their balance, walking, and stability. During t...

ECoG BMI for Motor and Speech Control

NCT ID: NCT03698149

This clinical trial, titled "ECoG BMI for Motor and Speech Control," is exploring a new way to help people with severe neurological conditions, such as ALS (amyotrophic lateral sclerosis), spinal c...

Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the Disease

NCT ID: NCT07025122