Clinical Trials for Myelodysplastic Syndromes

Find clinical trials for myelodysplastic syndromes. Discover research opportunities and treatment options in your area.

157 Active Trials Found

Showing 157 trials on this page

Page 1 of 8

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

NCT ID: NCT04256317

This clinical trial is studying a new treatment called ASTX030, which combines two medications, cedazuridine and azacitidine, to see how well they work for patients with certain blood disorders, in...

Recruiting

Phase: PHASE2 Type: interventional Locations: New Haven, Connecticut, United States, Rochester, New York, United States +28 more

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

NCT ID: NCT06303193

This clinical trial is studying a new medication called pacritinib to see if it can help treat myelodysplastic syndromes (MDS) and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in both adu...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research Study

NCT ID: NCT07102849

This study is focused on understanding bone marrow failure syndromes, which are conditions where the bone marrow doesn’t produce enough healthy blood cells. These problems can happen because the bo...

Not yet recruiting

Type: observational Locations: Bethesda, Maryland, United States

A Study of BGB-11417 in Participants With Myeloid Malignancies

NCT ID: NCT04771130

This clinical trial is studying a new drug called BGB-11417 to see how safe it is, how well it works, and what the best dose is for treating certain blood cancers, specifically Acute Myeloid Leukem...

Recruiting

Phase: PHASE1 Type: interventional Locations: Milwaukee, Wisconsin, United States, Duarte, California, United States +103 more

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

NCT ID: NCT06566742

This clinical trial is studying a medication called olutasidenib to see if it can help patients with certain blood disorders, specifically those with IDH1 mutations and conditions like Clonal Cytop...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

NCT ID: NCT05949684

The ELEMENT-MDS clinical trial is studying how effective and safe a medication called Luspatercept is for treating anemia in adults with Myelodysplastic Syndromes (MDS) who are not receiving blood ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Sioux Falls, South Dakota, United States, Chicago, Illinois, United States +324 more

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

NCT ID: NCT05490446

This clinical trial is studying a medication called tebapivat for people with a condition known as lower-risk myelodysplastic syndromes (LR-MDS), which causes anemia (a low level of red blood cells...

Recruiting

Phase: PHASE2 Type: interventional Locations: Durham, North Carolina, United States, Saint Louis, Missouri, United States +50 more

A Study of GLB-001 in Patients With Myeloid Malignancies

NCT ID: NCT06378437

This clinical trial, called GLB-001-02, is investigating a new treatment called GLB-001 for patients with certain blood cancers known as myeloid malignancies. These include conditions like polycyth...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chongqing, Chongqing, China, Beijing, Beijing, China +14 more

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

NCT ID: NCT06904482

This clinical trial is looking to find out if combining two types of stem cell donors—one from a family member and one from umbilical cord blood—can help people with certain blood cancers live long...

Recruiting

Phase: PHASE2 Type: interventional Locations: Cleveland, Ohio, United States

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT ID: NCT06788509

This study is a long-term safety check for people with certain blood cancers and some advanced solid tumors who have already participated in Janssen cancer studies. It’s an open-label, single-group...

Enrolling by invitation

Phase: PHASE1 Type: interventional Locations: Villejuif, France, Taipei City, Taiwan +23 more

Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants

NCT ID: NCT07019155

This clinical trial is studying a group of inherited disorders called hereditary hematopoietic malignancy (HHM) syndromes, which increase the risk of blood cancers like myelodysplastic syndromes (M...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies

NCT ID: NCT05588154

This clinical trial is studying myelodysplastic syndromes (MDS), which are disorders that affect blood stem cells and can lead to blood cancers. The goal of this study is to collect samples from he...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Home Blood Transfusions

NCT ID: NCT07121140

This clinical trial is exploring a new way to give blood transfusions to patients with certain blood cancers or bone marrow problems who need regular transfusions. Instead of coming into the hospit...

Recruiting

Phase: NA Type: interventional Locations: Philadelphia, Pennsylvania, United States

Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS

NCT ID: NCT05350748

This clinical trial is focused on understanding myelodysplastic syndromes (MDS), which are conditions where blood cells don't develop properly. There aren't many treatments available for MDS, so re...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

NCT ID: NCT03579875

This clinical trial is studying a new treatment for patients with inherited bone marrow failure disorders, such as Fanconi Anemia and Severe Aplastic Anemia. The goal of the trial is to see if a sp...

Recruiting

Phase: PHASE2 Type: interventional Locations: Minneapolis, Minnesota, United States

Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT)

NCT ID: NCT05444348

This clinical trial, called ACT, is focused on improving end-of-life care for patients with certain blood cancers, such as Multiple Myeloma, Acute Myeloid Leukemia, and Lymphoma. Many patients with...

Recruiting

Phase: NA Type: interventional Locations: Odense, Denmark, Aalborg, Denmark +5 more

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

NCT ID: NCT05320198

This clinical trial is studying a new treatment called DISC-0974 for people who have myelofibrosis or myelodysplastic syndrome, along with anemia (a condition where you have low red blood cells). T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, Philadelphia, Pennsylvania, United States +14 more

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

NCT ID: NCT06138587

This clinical trial is looking at a new treatment method called preemptive CIML NK cell therapy, designed to help prevent the return of certain types of blood cancers, including acute myeloid leuke...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Mosaic Trial for Stem Cell Transplant Recipients

NCT ID: NCT06960993

The Mosaic Trial is a research study designed to see if a special website can help adults with blood cancer who are getting stem cell transplants. The study will compare the experiences of patients...

Recruiting

Phase: NA Type: interventional Locations: Chicago, Illinois, United States, Washington, District Of Columbia, United States +1 more

Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory Myelodysplastic Syndromes

NCT ID: NCT06923488

This clinical trial is investigating a new treatment approach for patients with relapsed or refractory myelodysplastic syndromes (R/R MDS), a type of blood disorder. The study is testing the safety...

Recruiting

Phase: PHASE1 Type: interventional Locations: Morgantown, West Virginia, United States

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Prostate Cancer View clinical trials → Healthy View clinical trials →

Search All Trials Browse All Conditions