Clinical Trials for Myelodysplastic Syndromes

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT ID: NCT06788509

Mosaic Trial for Stem Cell Transplant Recipients

NCT ID: NCT06960993

The Mosaic Trial is a research study designed to see if a special website can help adults with blood cancer who are getting stem cell transplants. The study will compare the experiences of patients...

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

NCT ID: NCT06303193

This clinical trial is studying a new medication called pacritinib to see if it can help treat myelodysplastic syndromes (MDS) and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in both adu...

Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants

NCT ID: NCT07019155

This clinical trial is studying a group of inherited disorders called hereditary hematopoietic malignancy (HHM) syndromes, which increase the risk of blood cancers like myelodysplastic syndromes (M...

Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT

NCT ID: NCT06551584

This clinical trial is looking at a new treatment approach for patients with advanced blood cancers, such as acute myeloid leukemia and myelodysplastic syndromes. The main goal is to assess the saf...

A Study of BGB-11417 in Participants With Myeloid Malignancies

NCT ID: NCT04771130

This clinical trial is studying a new drug called BGB-11417 to see how safe it is, how well it works, and what the best dose is for treating certain blood cancers, specifically Acute Myeloid Leukem...

Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

NCT ID: NCT02211755

This clinical trial is studying a combination of two cancer-fighting drugs, bortezomib and clofarabine, in adults who have solid tumors or certain blood disorders that have not responded well to st...

Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia

NCT ID: NCT07071155

This clinical trial is studying a new treatment approach for people with certain rare blood cancers called myelodysplastic/myeloproliferative neoplasms (MDS/MPNs) or chronic neutrophilic leukemia (...

HEME Home Transfusion Program

NCT ID: NCT06487247

The HEME Home Transfusion Program is a research study designed to explore a new way of providing blood transfusions to patients with certain blood cancers, like leukemia and lymphoma, in the comfor...

OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study

NCT ID: NCT06270771

This clinical trial, titled "OURA Ring Wearable Testing in MDS Patients," is exploring whether using the OURA ring—a smart wearable device—can help monitor the health and quality of life of adults ...

Eltrombopag as a Novel Therapeutic Approach for Low-risk MDS and CMML With TET2 Mutations

NCT ID: NCT06630221

This clinical trial is investigating a drug called eltrombopag as a possible new treatment for patients with low-risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML) who ...

Umbilical Cord Blood Transplantation From Unrelated Donors

NCT ID: NCT03016806

This clinical trial is studying the use of umbilical cord blood stem cell transplantation as a treatment for various serious conditions such as acute leukemia, immune deficiency disorders, and cert...

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

NCT ID: NCT00935090

This clinical trial is studying a special type of imaging called 3'-deoxy-3'-[18F] fluorothymidine (FLT) PET imaging in patients who have various types of cancer, including brain tumors, leukemia, ...

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)

NCT ID: NCT04093570

A Telehealth Advance Care Planning Intervention

NCT ID: NCT05875805

This clinical trial is exploring how a telehealth program can help older patients with certain blood cancers, such as acute myeloid leukemia and myelodysplastic syndromes, communicate better about ...

Allo HSCT Using RIC and PTCy for Hematological Diseases

NCT ID: NCT05805605

This clinical trial is looking at a new approach to treating certain blood cancers, including various types of leukemia and lymphoma. The study is specifically evaluating a method called "Allo HSCT...

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

NCT ID: NCT06594445

This clinical trial, titled HM2023-05, is studying a new treatment called GTB-3650 for adults aged 18 and older who have certain types of blood cancer, specifically Acute Myeloid Leukemia (AML) or ...

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

NCT ID: NCT05949684

The ELEMENT-MDS clinical trial is studying how effective and safe a medication called Luspatercept is for treating anemia in adults with Myelodysplastic Syndromes (MDS) who are not receiving blood ...

A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome

NCT ID: NCT06847867

This clinical trial is studying a medication called momelotinib to see if it is safe and effective for people with low-risk myelodysplastic syndromes (MDS), a type of blood disorder that affects ho...

Registry of Older Patients With Cancer

NCT ID: NCT01137825

This clinical trial, called the Registry of Older Patients With Cancer, aims to collect important information about older adults who have cancer. The goal is to better understand how cancer affects...