Clinical Trials for Neuro-Degenerative Disease

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

NCT ID: NCT04079179

This clinical trial is investigating a medication called cobimetinib for patients with Langerhans cell histiocytosis (LCH) and other related conditions that have not responded to previous treatment...

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

NCT ID: NCT06151600

This clinical trial is studying Charcot-Marie-Tooth Disease, Type 4J (CMT4J), a genetic condition that affects the nerves and can lead to muscle weakness and problems with movement. The researchers...

Tocotrienols in Parkinson's Disease (PD)

NCT ID: NCT04491383

This clinical trial is studying the effects of a substance called tocotrienols (HOV-12020) on people with Parkinson's disease (PD). Researchers want to see if taking tocotrienols can help delay the...

Cross Cultural Validation of the Italian Version of the Clinical Assessment of Dysphagia in Neurodegeneration

NCT ID: NCT05733494

This clinical trial is focused on creating and testing an Italian version of a tool called the Clinical Assessment of Dysphagia in Neurodegeneration (CADN). Dysphagia is a condition where people ha...

Retinal Imaging in Neurodegenerative Disease

NCT ID: NCT03233646

This clinical trial, titled "Retinal Imaging in Neurodegenerative Disease," is focused on using advanced imaging techniques to better understand eye health in people with various brain disorders, i...

Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases.

NCT ID: NCT04880356

The Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases is a research trial aimed at learning more about very rare inherited conditions that affect the brain...

Evaluation of the Safety, Tolerability and PK Characteristics of GV1001 in Healthy Subjects

NCT ID: NCT06625710

This clinical trial is studying a new treatment called GV1001 to see how safe it is and how well the body can handle it. The trial involves healthy adults and aims to find out the effects of differ...

Establishment of Genetic Basis for Neurological Disease by Genetic Screening

NCT ID: NCT03322306

Digital Diagnostics and Intervention Services for Parkinson's Disease

NCT ID: NCT06534177

This clinical trial is studying new digital tools to help assess and improve the movement of people with Parkinson's disease. Currently, patients see their doctors only once every 12 to 18 months, ...

Persons With Dementia and Their Extended Family Caregivers

NCT ID: NCT04863859

This clinical trial is focused on understanding the experiences of extended family members who care for loved ones living with dementia. As many families are now sharing caregiving responsibilities...

Synaptic Density, Tau and Multiparametric PET-MR in Brain Trauma, Stroke and Mild Cognitive or Behavioral Impairment.

NCT ID: NCT03514524

3T MRI in Patients With Deep Brain Stimulation (DBS)

NCT ID: NCT03153670

This clinical trial is studying how deep brain stimulation (DBS), a treatment used for conditions like advanced Parkinson's disease and certain movement disorders, affects brain function. Researche...

Visualization of Neural Targets With 3T MRI

NCT ID: NCT05175417

This clinical trial is studying how to improve brain imaging for patients with neuro-degenerative diseases who are preparing for certain types of brain surgeries. The researchers are using a specia...

Białystok PLUS - Polish Longitudinal University Study

NCT ID: NCT03197363

Identifying Biomarkers in Alzheimer's Disease

NCT ID: NCT05655650

This clinical trial is focused on finding new ways to detect Alzheimer’s disease (AD) early, which is important because there is currently no cure for this serious brain condition. The researchers ...