Clinical Trials for Opioid Use

Find clinical trials for opioid use. Discover research opportunities and treatment options in your area.

117 Active Trials Found

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Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

NCT ID: NCT06103370

This clinical trial is focused on finding better ways to help people who inject drugs get tested for HIV and connect to important health services in Maryland. The study will explore if using social...

Not yet recruiting

Phase: NA Type: interventional Locations: Baltimore, Maryland, United States

Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism

NCT ID: NCT04798469

This clinical trial is looking at how testosterone replacement therapy may help men who are experiencing chronic spinal pain due to long-term opioid use, which can lower testosterone levels (a cond...

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia

NCT ID: NCT06905340

This clinical trial is studying whether using a special device called the Nociception Level Index (NOL) can help doctors give the right amount of pain medication (sufentanil) during surgery. The go...

Phase: NA Type: interventional Locations: Hamburg, , Germany

Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects

NCT ID: NCT06981195

This clinical trial is studying how a medication called lemborexant can help improve sleep and mood in people with Opioid Use Disorder who are already receiving treatment with buprenorphine. The re...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Richmond, Virginia, United States

Opioid Dispensing Device for Post-Operative Pain in Cancer Patients

NCT ID: NCT05585788

This clinical trial is studying a new device called Addinex, which is designed to safely store and dispense opioid medications for pain relief after surgery. Specifically, the study is focused on h...

Phase: NA Type: interventional Locations: New York, New York, United States

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

NCT ID: NCT04927143

This clinical trial, titled "Encouraging Abstinence Behavior in a Drug Epidemic," is studying how financial incentives can help people struggling with opioid or cocaine use disorders to stay sober....

Phase: NA Type: interventional Locations: Oconomowoc, Wisconsin, United States, Wauwatosa, Wisconsin, United States +1 more

Effect of MGRNOX Index-Guided General Anesthesia on Opioid Consumption in Patients

NCT ID: NCT07004686

This clinical trial is investigating how a new method of monitoring pain during surgery, called the MGRNOX index, can help reduce the amount of opioid medication used for pain relief in patients un...

Phase: NA Type: interventional Locations: Shenzhen, Guangdong, China

Outcome of Multimodal Anesthesia Bern

NCT ID: NCT06985069

This clinical trial is looking at a new way to manage pain during and after major surgery by using a method called multimodal anesthesia (MMA). Instead of relying heavily on opioids, which can have...

Not yet recruiting

Phase: NA Type: interventional Locations: Bern, , Switzerland

Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery

NCT ID: NCT06528288

This clinical trial is looking at how different methods of providing pain relief affect patients after lumbar fusion surgery, which is a procedure to join two or more bones in the lower back. Speci...

Phase: NA Type: interventional Locations: Worcester, Massachusetts, United States

Opioid Use After Laparoscopic Salpingectomy

NCT ID: NCT06434233

This clinical trial is studying how well different pain management methods work for women who are having a laparoscopic salpingectomy, a minimally invasive procedure that involves removing the fall...

Phase: PHASE4 Type: interventional Locations: Baltimore, Maryland, United States

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

NCT ID: NCT06903819

This clinical trial is investigating whether a single dose of ketamine given during surgery can help patients with serious orthopedic injuries manage their pain better, reduce their need for opioid...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Lubbock, Texas, United States, Lubbock, Texas, United States

rTMS as Add on Treatment for Substance Use Disorders

NCT ID: NCT06963476

This clinical trial is exploring a treatment called repetitive Transcranial Magnetic Stimulation (rTMS) to help people with Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD). The study aims ...

Not yet recruiting

Phase: NA Type: interventional Locations: Hartford, Connecticut, United States

PRIDE III Prison Interventions and HIV Prevention Collaboration

NCT ID: NCT06962033

The PRIDE III trial is exploring how to improve access to a treatment called Opioid Agonist Therapy (OAT) for people who use opioids and are involved with the justice system, such as prisons and pr...

Phase: NA Type: interventional Locations: New Haven, Connecticut, United States, Tbilisi, , Georgia +3 more

Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)

NCT ID: NCT04895306

The TRAPP Trial is a study designed to find out if testosterone replacement therapy can help postmenopausal women with chronic back pain who are currently taking opioid medications. Specifically, t...

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

THRIVE: Culturally AdapTed Harm Reduction Intervention

NCT ID: NCT06609278

The THRIVE trial is studying a special program designed to help Black adults who are misusing opioids (like prescription painkillers) and stimulants (such as cocaine or meth). The goal is to see if...

Phase: NA Type: interventional Locations: Cincinnati, Ohio, United States, Louisville, Kentucky, United States +1 more

Managing Opioid Related Sleep Apnea With Acetazolamide

NCT ID: NCT06043830

This clinical trial is studying whether a medication called acetazolamide can help improve sleep-related breathing problems in patients who have chronic pain and use opioids. These breathing issues...

Phase: PHASE2 Type: interventional Locations: San Diego, California, United States, San Diego, California, United States

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs

NCT ID: NCT05192434

This clinical trial, called "TIARAS," aims to find out if a special program can help reduce the risk of HIV among women who inject drugs. The program includes support for managing trauma and encour...

Phase: NA Type: interventional Locations: Philadelphia, Pennsylvania, United States

fMRI and Opioid Abstinence

NCT ID: NCT06651333

This clinical trial is studying how certain brain activity patterns may relate to the risk of relapse in people recovering from opioid dependence. The researchers are particularly interested in tho...

Type: observational Locations: New Haven, Connecticut, United States

Neuroimaging of Opioid Phase (OPAL)

NCT ID: NCT05905419

The OPAL study is looking to learn more about how the brains of women with chronic pain, particularly those who use opioids, compare to the brains of healthy women. By doing this, researchers hope ...

Phase: NA Type: interventional Locations: Durham, North Carolina, United States

Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls

NCT ID: NCT04401917

This clinical trial is researching brain inflammation in people who have HIV, those who use opioids, and healthy individuals. The goal is to see how a special imaging drug, called \[18F\]NOS, behav...

Phase: EARLY_PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States

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