Clinical Trials for Osteosarcoma

Find clinical trials for osteosarcoma. Discover research opportunities and treatment options in your area.

69 Active Trials Found

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Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT ID: NCT06625190

This clinical trial is investigating a new treatment approach for certain solid tumors in young patients, including conditions like neuroblastoma and rhabdomyosarcoma. The treatment involves using ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Gainesville, Florida, United States

An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

NCT ID: NCT06064682

This clinical trial, called "An Organoid-based Functional Precision Medicine Trial in Osteosarcoma," is focused on understanding how patients with osteosarcoma, a type of bone cancer, might respond...

Recruiting

Type: observational Locations: Los Angeles, California, United States

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

NCT ID: NCT05235165

This clinical trial is comparing two different surgical methods to treat patients with osteosarcoma, a type of bone cancer that has spread to the lungs. The two methods are open thoracic surgery, w...

Recruiting

Phase: PHASE3 Type: interventional Locations: New Haven, Connecticut, United States, Brooklyn, New York, United States +251 more

Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas

NCT ID: NCT07052383

This clinical trial is studying a new treatment called DIT309, which is a type of CAR-T cell therapy designed to fight advanced bone and soft tissue sarcomas—types of cancers that affect bones and ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

NCT ID: NCT06341712

This clinical trial is investigating the effects of a medication called cabozantinib combined with best supportive care (BSC) compared to BSC alone in children, adolescents, and young adults with a...

Recruiting

Phase: PHASE2 Type: interventional Locations: Norfolk, Virginia, United States, Lyon, , France +73 more

SPEARHEAD-3 Pediatric Study

NCT ID: NCT05642455

The SPEARHEAD-3 Pediatric Study is a clinical trial looking at a new treatment called afamitresgene autoleucel for children and young adults aged 2 to 21 years who have advanced cancers, specifical...

Recruiting

Phase: PHASE1 Type: interventional Locations: Palo Alto, California, United States, Boston, Massachusetts, United States +13 more

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT ID: NCT03618381

This clinical trial is looking at a new type of treatment called EGFR806 CAR T Cell Immunotherapy for children and young adults with certain types of solid tumors that have returned or didn’t respo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Cabozantinib With Ifosfamide in Ewing's Sarcoma and Osteosarcoma

NCT ID: NCT06156410

This clinical trial is studying the combination of two drugs, cabozantinib and ifosfamide, to see how safe and effective they are for treating children and adults with Ewing sarcoma and osteosarcom...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Philadelphia, Pennsylvania, United States +3 more

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

NCT ID: NCT01790152

This clinical trial is exploring how a medication called dexrazoxane hydrochloride affects certain markers in the blood that are linked to heart problems, like cardiomyopathy and heart failure, in ...

Recruiting

Type: observational Locations: New Haven, Connecticut, United States, Lebanon, New Hampshire, United States +77 more

PET-imaging of Two Vartumabs in Patients With Solid Tumors

NCT ID: NCT06645808

The VARTUTRACE clinical trial is studying two new imaging agents that can help doctors see and understand solid tumors, which are types of cancer that form in various organs. This study is particul...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Groningen, , Netherlands

Early Ageing During Therapy in AYA Cancer Patients

NCT ID: NCT05062707

This clinical trial, titled "Early Ageing During Therapy in AYA Cancer Patients," is studying how cancer treatments affect young adults aged 18 to 39. The researchers want to understand if these tr...

Recruiting

Type: observational Locations: Groningen, , Netherlands, Groningen, , Netherlands

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

NCT ID: NCT06521567

This clinical trial is studying a combination of two medications, cobolimab and dostarlimab, to find out the safest and most effective doses for children and young adults with advanced cancer, spec...

Recruiting

Phase: PHASE1 Type: interventional Locations: Roma, Lazio, Italy, Barcelona, , Spain +35 more

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

NCT ID: NCT03442465

This clinical trial is examining how well patients recover and regain function after undergoing surgery to treat bone tumors, specifically types like osteosarcoma and chondrosarcoma. The study will...

Recruiting

Type: observational Locations: New York, New York, United States, Middletown, New Jersey, United States +2 more

Pediatric PET/MR Image Registry

NCT ID: NCT03458520

The Pediatric PET/MR Image Registry is a clinical trial aimed at understanding how different imaging techniques can help in diagnosing tumors in children and young adults. Specifically, the study i...

Recruiting

Type: observational Locations: Palo Alto, California, United States

Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma

NCT ID: NCT06562673

This clinical trial is studying a new treatment approach for osteosarcoma, a type of bone cancer. The researchers want to find out if a combination of two medications, cisplatin and rh-endostatin (...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, , China

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

NCT ID: NCT03721068

This clinical trial is studying a new treatment for children and young adults with certain types of hard-to-treat cancers, specifically neuroblastoma and osteosarcoma. The treatment combines two po...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chapel Hill, North Carolina, United States, Atlanta, Georgia, United States

Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma

NCT ID: NCT06492954

This clinical trial is studying a treatment approach for patients with a type of cancer called osteosarcoma, specifically when it has come back in the lungs after initial treatment. The trial is te...

Recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT ID: NCT04897321

The 3CAR trial is a research study looking at a new type of treatment called immunotherapy for children and young adults (up to 21 years old) with specific types of solid tumors, such as neuroblast...

Recruiting

Phase: PHASE1 Type: interventional Locations: Memphis, Tennessee, United States

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

NCT ID: NCT06500819

This clinical trial is testing a new type of treatment called B7-H3CAR T-cell therapy for children and young adults with certain solid tumors, like neuroblastoma, sarcoma, and osteosarcoma, that ha...

Recruiting

Phase: PHASE1 Type: interventional Locations: Palo Alto, California, United States

Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure

NCT ID: NCT06935409

This clinical trial is studying a new treatment called HS-20093 to see how well it works compared to a combination of two existing medications, gemcitabine and docetaxel, in treating osteosarcoma. ...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Beijing, , China, Beijing, , China

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