Clinical Trials for Parkinson Disease

Bacillus Subtilis in Parkinson's Disease

NCT ID: NCT06487975

This clinical trial is studying the effects of a supplement called Bacillus Subtilis on people with Parkinson's disease. Researchers want to see if taking this supplement can change certain markers...

The Effect of Spinal Mobilization on Respiratory Parameters in Parkinson's Disease Patients

NCT ID: NCT04941326

This clinical trial is looking at how certain physical therapy techniques, specifically spinal mobilization and diaphragmatic breathing exercises, can help improve breathing in people with Parkinso...

Genetic Studies of Lysosomal Storage Disorders

NCT ID: NCT00001215

Parkinson's Disease Biomarkers in Nerve Cells in the Gut

NCT ID: NCT05347407

This clinical trial is investigating how nerve cells in the gut might provide clues about Parkinson's disease. The gut has its own nervous system, often called the "second brain," and researchers b...

Self-controlled Practice on Motor Learning and Motivation in Parkinson's Disease

NCT ID: NCT07028515

This clinical trial is studying a new way to help people with Parkinson’s disease improve their movement skills and motivation during rehabilitation. People with Parkinson’s often find it hard to l...

A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's Disease

NCT ID: NCT06584383

This clinical trial is studying a new treatment called Exablate MR-guided Focused Ultrasound Subthalamotomy for people with early-stage Parkinson's Disease. The goal is to see if this treatment is ...

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants With Advanced Parkinson Disease

NCT ID: NCT06965374

This clinical trial is studying how well a medication called Foslevodopa/Foscarbidopa works for adults with advanced Parkinson's disease, a condition that affects movement and worsens over time. Th...

Apathy in Parkinson Disease TMS Study

NCT ID: NCT06087926

The Apathy in Parkinson Disease TMS Study is a clinical trial that aims to find new ways to help patients with Parkinson's disease who struggle with apathy, which means they have trouble feeling mo...

The Efficacy and Safety of Precision REpetitive Transcranial Magnetic Stimulation in Alleviating Motor Symptom in Parkinson's Disease

NCT ID: NCT06383247

This clinical trial is studying a treatment called repetitive transcranial magnetic stimulation (rTMS) to see if it can help improve the motor symptoms of Parkinson's disease. rTMS is a non-invasiv...

SegwayPD: The Effect of Sensory-augmented Postural Training Using Segway on Motor and Cognitive Function in Individuals With Parkinson's Disease

NCT ID: NCT05982730

The SegwayPD clinical trial is studying how a special type of training can help people with Parkinson's Disease (PD) improve their balance and coordination. The training uses a Segway, which is a t...

Cognitive-motor Training in Parkinson Disease

NCT ID: NCT06588439

This clinical trial is exploring a type of training called stepping-based cognitive-motor training for people with Parkinson's disease (PD). The goal is to see if this training can help improve wal...

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

NCT ID: NCT03664609

This clinical trial is looking at the outcomes of a treatment called Deep Brain Stimulation (DBS) for people with conditions like Parkinson's Disease, Essential Tremor, and Dystonia. DBS involves i...

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

NCT ID: NCT06680830

This clinical trial is studying a new treatment called NEU-411 for people aged 50 to 80 who have early Parkinson's Disease (PD) and have a specific genetic profile that suggests their symptoms may ...

The Parkinson's Disease Case-Control Study

NCT ID: NCT06848192

The Parkinson's Disease Case-Control Study is looking at the differences in gut fungi between people with Parkinson's disease and healthy individuals to better understand how these differences migh...

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

NCT ID: NCT06976268

This clinical trial is looking at a new treatment called BHV-8000 to see if it is effective, safe, and tolerable for adults with early Parkinson's disease. Parkinson's disease (PD) is a condition t...

Natural History Study of Synucleinopathies

NCT ID: NCT01799915

This clinical trial, called the Natural History Study of Synucleinopathies, is looking into a group of rare neurological disorders that affect movement and cognition due to the buildup of a protein...

Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease

NCT ID: NCT07022522

This clinical trial is studying how different types of electrical stimulation in a specific brain area called the subthalamic nucleus (STN) can improve the ability to control impulses and attention...

Severity of Sarcopenia in Parkinson's Disease

NCT ID: NCT07014514

This clinical trial is studying the severity of sarcopenia, which is the loss of muscle mass and strength, in people with Parkinson's disease. The researchers want to understand how this condition ...

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

NCT ID: NCT04620382

This clinical trial is studying how two different treatments—midodrine, a medication, and abdominal compression, which involves wearing a special device that applies pressure to the abdomen—affect ...

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

NCT ID: NCT06553625

The RAPID for CNS study is looking at the outcomes of a treatment called radiofrequency (RF) ablation, which is used to help manage conditions like Parkinson's disease, dystonia, essential tremor, ...