Clinical Trials for Parkinson Disease

Find clinical trials for parkinson disease. Discover research opportunities and treatment options in your area.

604 Active Trials Found

Showing 604 trials on this page

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The Study is Being Conducted to Evaluate the Safety and Efficacy of XJN010 Nasal Spray in Patients With Parkinson's Disease Experiencing Off Episodes

NCT ID: NCT07156773

This trial is studying the nasal spray XJN010 to see if it is safe, how the body handles it, and whether it can help people with Parkinson’s disease who experience “off” episodes (times when their ...

Recruiting

Phase: PHASE2 Type: interventional

Role of Silymarin in Neuroprotection and Symptom Management in Parkinson's Disease

NCT ID: NCT07001150

This clinical trial is looking at a substance called silymarin to see if it can help protect the brain and manage symptoms for people with Parkinson's disease. Parkinson's is a condition that affec...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tanta, Egypt

Which Tools Better Predict Fall Risk in Parkinson's Disease: A Comparative Study of Objective, Self-Reported, and Functional Balance Assessment

NCT ID: NCT07148700

This clinical trial is studying how well different tools can predict the risk of falls in people with Parkinson’s disease (PD). Falls are common in PD and can happen often, so it’s important to fin...

Recruiting

Type: observational

A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease

NCT ID: NCT07157735

DAPA-PD is a Phase II clinical trial that tests whether dapansutrile, a medicine designed to calm inflammation in the body and brain, can be safe and potentially help people with early Parkinson’s ...

Not yet recruiting

Phase: PHASE2 Type: interventional

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

NCT ID: NCT07154511

This clinical trial is studying whether a supplement called tributyrin can help improve memory, thinking, walking, and balance in adults who have Parkinson’s disease or Parkinson’s disease dementia...

Recruiting

Phase: PHASE1 Type: interventional

Genetic Studies of Lysosomal Storage Disorders

NCT ID: NCT00001215

This is an ongoing observational study run by the National Institutes of Health to learn more about lysosomal storage disorders, especially Gaucher disease, and how these conditions can relate to m...

Enrolling by invitation

Type: observational Locations: Bethesda, Maryland, United States

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

NCT ID: NCT06765668

This clinical trial is studying a medication called CREXONT, which combines two drugs, Carbidopa and Levodopa, in extended-release capsules. The main goal is to see how well CREXONT works and how s...

Recruiting

Phase: PHASE4 Type: interventional Locations: Kansas City, Kansas, United States, Little Rock, Arkansas, United States +26 more

Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

NCT ID: NCT07110376

This clinical trial is studying how different settings of deep brain stimulation (DBS) – a treatment that uses electrical pulses to help control Parkinson’s symptoms – affect brain activity during ...

Not yet recruiting

Phase: NA Type: interventional

BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease

NCT ID: NCT07138560

This clinical trial is studying a new extended-release form of a Parkinson’s medication called IPX203 (brand name Crexont®). The main goal is to see if this medicine can help people with Parkinson’...

Recruiting

Phase: PHASE4 Type: interventional Locations: Cleveland, Ohio, United States

SL-START - SubLingual Apomorphine Schemes of TitrAtion in Real-world Treatment

NCT ID: NCT07145190

This clinical trial, called SL-START, is studying a treatment for Parkinson’s disease using a medicine called sublingual apomorphine (SL-APO), which is placed under the tongue to help manage sympto...

Not yet recruiting

Type: observational

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

NCT ID: NCT04715984

This clinical trial is focused on understanding how certain areas of the brain contribute to cognitive problems in people with Parkinson's disease. Researchers want to learn more about the brain's ...

Recruiting

Phase: NA Type: interventional Locations: Nashville, Tennessee, United States

Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation

NCT ID: NCT05933681

This clinical trial is studying how Deep Brain Stimulation (DBS) affects thinking and memory in patients with Parkinson's Disease. The goal is to find specific markers in the brain that can help re...

Recruiting

Phase: NA Type: interventional Locations: Nashville, Tennessee, United States

Effect of a Vibrating Therapy Ball on Tremor and Daily Activities in Patients With Different Tremor Syndroms

NCT ID: NCT07134634

This clinical trial is testing a special vibrating therapy ball called the VILIM ball to see if it can help reduce hand tremors in people with Parkinson’s disease and other types of tremor. Tremors...

Recruiting

Type: observational Locations: Beelitz, Brandenburg, Germany

Social & QoL Behaviors in Parkinson's Disease

NCT ID: NCT06385184

This clinical trial is studying how Parkinson's Disease affects people's social behaviors and overall quality of life compared to individuals without the disease who are of the same age. Researcher...

Recruiting

Type: observational Locations: Washington, District Of Columbia, United States

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

NCT ID: NCT06680830

This clinical trial is studying a new treatment called NEU-411 for people aged 50 to 80 who have early Parkinson's Disease (PD) and have a specific genetic profile that suggests their symptoms may ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Kansas City, Kansas, United States, Houston, Texas, United States +46 more

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

NCT ID: NCT06976268

This clinical trial is looking at a new treatment called BHV-8000 to see if it is effective, safe, and tolerable for adults with early Parkinson's disease. Parkinson's disease (PD) is a condition t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boca Raton, Florida, United States, Farmington Hills, Michigan, United States +3 more

Deciphering the Mechanisms of Central BP Regulation in Patients With PD Associated With Orthostatic Hypotension

NCT ID: NCT07139756

This clinical trial is studying how the brain controls blood pressure in people with Parkinson’s disease (PD), especially those who experience a condition called orthostatic hypotension (OH). OH me...

Not yet recruiting

Type: observational Locations: Lausanne, Vaud, Switzerland

Validation of a Novel Functional Food Designed to Meet the Nutritional Needs of People Living With Parkinson's Disease

NCT ID: NCT06697626

This clinical trial is studying a new functional drink designed to help people with Parkinson's disease (PD) who often suffer from constipation. Constipation is a common problem for many individual...

Recruiting

Phase: NA Type: interventional Locations: Coleraine, County Londonderry, United Kingdom

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

NCT ID: NCT04127578

The PROPEL trial is a research study looking at a new treatment called PR001 (LY3884961) for patients with Parkinson's disease who have a specific genetic mutation known as GBA1. This trial is in i...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ramat Gan, Israel, Orlando, Florida, United States +15 more

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

NCT ID: NCT06285643

This clinical trial, called REGENERATE-PD, is studying a new treatment for adults with moderate Parkinson's Disease, specifically looking at a gene therapy called AAV2-GDNF. The goal is to see if t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Philadelphia, Pennsylvania, United States +55 more

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