Clinical Trials for Parkinson Disease

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

NCT ID: NCT06621602

This clinical trial is studying a substance called phosphorylated alpha-synuclein (P-SYN) to see how it relates to Parkinson's disease and REM Behavior Disorder. Researchers will take small skin sa...

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

NCT ID: NCT04477785

The Parkinson Progression Marker Initiative (PPMI) is a long-term study designed to better understand how Parkinson's disease (PD) progresses over time. The goal is to find specific markers—like cl...

Gamma Sensory Flicker for Parkinson's Disease Patients With Freezing of Gait

NCT ID: NCT06295458

This clinical trial is studying the effects of gamma light on people with Parkinson's disease who experience a specific walking problem called Freezing of Gait (FOG). FOG is when a person's feet se...

Everyday Memory Impairment in PD-related Cognitive Decline

NCT ID: NCT04474379

This clinical trial is studying memory problems that can happen in people with Parkinson’s disease, especially those who have mild difficulties with thinking and memory but do not have dementia. Th...

Self-controlled Practice on Motor Learning and Motivation in Parkinson's Disease

NCT ID: NCT07028515

This clinical trial is studying a new way to help people with Parkinson’s disease improve their movement skills and motivation during rehabilitation. People with Parkinson’s often find it hard to l...

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

NCT ID: NCT06809400

This clinical trial is studying a new treatment called LY4006896 to see how safe it is and how it works in both healthy people and those with Parkinson's disease. Parkinson's disease is a condition...

Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease

NCT ID: NCT06092125

This clinical trial is looking at a special type of brain scan called PET/MR imaging to help diagnose and treat serious brain conditions like Alzheimer's disease, Parkinson's disease, epilepsy, and...

Visuomotor Control in Parkinson Disease

NCT ID: NCT06918938

This clinical trial is studying how people with Parkinson's disease (PD) process visual information and how it affects their movements, especially in daily activities like walking and writing. Rese...

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

NCT ID: NCT06680830

This clinical trial is studying a new treatment called NEU-411 for people aged 50 to 80 who have early Parkinson's Disease (PD) and have a specific genetic profile that suggests their symptoms may ...

Genetic Studies of Lysosomal Storage Disorders

NCT ID: NCT00001215

A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's

NCT ID: NCT04664634

This clinical trial is exploring a new digital tool designed to help patients with Parkinson's disease who have difficulty swallowing, a condition known as dysphagia, and issues with excessive droo...

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

NCT ID: NCT06638944

This clinical trial is studying a new device called i-Phagia, which is a wearable technology that helps people with swallowing difficulties, known as dysphagia. This condition is common in individu...

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

NCT ID: NCT03664609

This clinical trial is looking at the outcomes of a treatment called Deep Brain Stimulation (DBS) for people with conditions like Parkinson's Disease, Essential Tremor, and Dystonia. DBS involves i...

Study on Preliminary Safety and Efficacy of the ARC-IM Therapy to Alleviate Locomotor Deficits in People With Parkinson's Disease

NCT ID: NCT06295614

This clinical trial is studying a new treatment called ARC-IM therapy to help improve movement difficulties in people with Parkinson's disease. The therapy uses a technique called spinal cord stimu...

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

NCT ID: NCT07056361

This clinical trial is studying how electrical stimulation of specific areas deep in the brain can improve movement and muscle control in people with movement disorders like essential tremor and Pa...

Mediterranean Diet Effects on Parkinson's Disease

NCT ID: NCT06705517

This clinical trial is exploring the effects of the Mediterranean diet on patients with Parkinson's disease (PD). Researchers want to see if following this diet can help improve both movement and n...

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

NCT ID: NCT06553625

The RAPID for CNS study is looking at the outcomes of a treatment called radiofrequency (RF) ablation, which is used to help manage conditions like Parkinson's disease, dystonia, essential tremor, ...

Percept Transitions in FOG and PD

NCT ID: NCT06848205

This clinical trial, called Percept Transitions in FOG and PD, is focused on understanding freezing of gait (FOG) in people with Parkinson's disease (PD). Freezing of gait is when someone suddenly ...

Unlocking Movement Potential: Enhancing Parkinson's Disease Treatment With Robotic EksoSkeleton

NCT ID: NCT06225830

The clinical trial titled "Unlocking Movement Potential" is studying the effects of a robotic device called the Eksobionic Exoskeleton (Esko) on people with Parkinson's disease. The goal is to see ...

Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder

NCT ID: NCT06467461

This clinical trial is studying a condition called serotonergic REM sleep behavior disorder (5-HT RBD) and its potential links to neurodegenerative diseases like dementia with Lewy bodies and Parki...